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Institution

Shanghai University

EducationShanghai, Shanghai, China
About: Shanghai University is a education organization based out in Shanghai, Shanghai, China. It is known for research contribution in the topics: Microstructure & Graphene. The organization has 59583 authors who have published 56840 publications receiving 753549 citations. The organization is also known as: Shànghǎi Dàxué.


Papers
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Journal ArticleDOI
TL;DR: Theabrownin alters the gut microbiota in mice and humans, predominantly suppressing microbes associated with bile-salt hydrolase (BSH) activity, and it is suggested that decreased intestinal BSH microbes and/or decreased FXR-FGF15 signaling may be potential anti- hypercholesterolemia and anti-hyperlipidemia therapies.
Abstract: Pu-erh tea displays cholesterol-lowering properties, but the underlying mechanism has not been elucidated. Theabrownin is one of the most active and abundant pigments in Pu-erh tea. Here, we show that theabrownin alters the gut microbiota in mice and humans, predominantly suppressing microbes associated with bile-salt hydrolase (BSH) activity. Theabrownin increases the levels of ileal conjugated bile acids (BAs) which, in turn, inhibit the intestinal FXR-FGF15 signaling pathway, resulting in increased hepatic production and fecal excretion of BAs, reduced hepatic cholesterol, and decreased lipogenesis. The inhibition of intestinal FXR-FGF15 signaling is accompanied by increased gene expression of enzymes in the alternative BA synthetic pathway, production of hepatic chenodeoxycholic acid, activation of hepatic FXR, and hepatic lipolysis. Our results shed light into the mechanisms behind the cholesterol- and lipid-lowering effects of Pu-erh tea, and suggest that decreased intestinal BSH microbes and/or decreased FXR-FGF15 signaling may be potential anti-hypercholesterolemia and anti-hyperlipidemia therapies. Pu-erh tea displays cholesterol-lowering properties. Here, Huang et al. show that this is mostly due to the action of a pigment in Pu-erh tea that induces changes in certain gut microbiota and bile acid levels, thus modulating the gut-liver metabolic axis.

341 citations

Journal ArticleDOI
TL;DR: From the simulation of space-time evolution of the vehicle headway, it is shown that the traffic jam is suppressed efficiently with taking into account the information about the motion of more vehicles in front, and the analytical result is consonant with the simulation one.
Abstract: An extended car following model is proposed by incorporating an intelligent transportation system in traffic. The stability condition of this model is obtained by using the linear stability theory. The results show that anticipating the behavior of more vehicles ahead leads to the stabilization of traffic systems. The modified Korteweg-de Vries equation (the mKdV equation, for short) near the critical point is derived by applying the reductive perturbation method. The traffic jam could be thus described by the kink-antikink soliton solution for the mKdV equation. From the simulation of space-time evolution of the vehicle headway, it is shown that the traffic jam is suppressed efficiently with taking into account the information about the motion of more vehicles in front, and the analytical result is consonant with the simulation one.

341 citations

Journal ArticleDOI
TL;DR: The sheet-on-sheet nanocomposite showed highly reversible large capacities at a common current of 0.1 C and good rate capabilities, and it is believed that the mechanical stability and electrical conductivity of NiO nanosheets are increased by graphene nanOSheets (GNS).
Abstract: This paper reports a hydrothermal preparation of NiO–graphene sheet-on-sheet and nanoparticle-on-sheet nanostructures. The sheet-on-sheet nanocomposite showed highly reversible large capacities at a common current of 0.1 C and good rate capabilities. A large initial charge capacity of 1056 mAh/g was observed for the sheet-on-sheet composite at 0.1 C, which decreased by only 2.4% to 1031 mAh/g after 40 cycles of discharge and charge. This cycling performance is better than that of NiO nanosheets, graphene nanosheets, NiO-graphene nanoparticle-on-sheet, and previous carbon/carbon nanotube supported NiO composites. It is believed that the mechanical stability and electrical conductivity of NiO nanosheets are increased by graphene nanosheets (GNS), the aggregation or restacking of which to graphite platelets are, on the other hand, effectively prevented by NiO nanosheets.

340 citations

Journal ArticleDOI
TL;DR: In this paper, hybrid nanocomposites based on Fe-based MOF and graphitic carbon nitride (g-C3N4) were developed by a facile solvothermal method.

339 citations

Journal ArticleDOI
TL;DR: This paper presents a collection of Raman spectra of 18 kinds of amino acids and their aqueous solutions that can serve as references for the interpretation of RamaSpectra of proteins and biological materials.

338 citations


Authors

Showing all 59993 results

NameH-indexPapersCitations
Zhong Lin Wang2452529259003
Yang Yang1712644153049
Yang Liu1292506122380
Zhen Li127171271351
Xin Wang121150364930
Jian Liu117209073156
Xin Li114277871389
Wei Zhang112118993641
Jianjun Liu112104071032
Liquan Chen11168944229
Jin-Quan Yu11143843324
Jonathan L. Sessler11199748758
Peng Wang108167254529
Qian Wang108214865557
Wei Zhang104291164923
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023182
2022741
20216,318
20205,569
20195,063
20184,235