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Showing papers by "Sichuan University published in 2003"


Journal ArticleDOI
TL;DR: Optimal fusion rules based on the best linear unbiased estimation (BLUE), the weighted least squares (WLS), and their generalized versions are presented for cases with complete, incomplete, or no prior information.
Abstract: This paper deals with data (or information) fusion for the purpose of estimation. Three estimation fusion architectures are considered: centralized, distributed, and hybrid. A unified linear model and a general framework for these three architectures are established. Optimal fusion rules based on the best linear unbiased estimation (BLUE), the weighted least squares (WLS), and their generalized versions are presented for cases with complete, incomplete, or no prior information. These rules are more general and flexible, and have wider applicability than previous results. For example, they are in a unified form that is optimal for all of the three fusion architectures with arbitrary correlation of local estimates or observation errors across sensors or across time. They are also in explicit forms convenient for implementation. The optimal fusion rules presented are not limited to linear data models. Illustrative numerical results are provided to verify the fusion rules and demonstrate how these fusion rules can be used in cases with complete, incomplete, or no prior information.

482 citations


Journal ArticleDOI
TL;DR: The greater surface roughness, higher surface energy and more surface hydroxyl groups resulted in greater numbers of adhered osteoblasts and higher cell activity, suggesting that the interactions between the cells and the titanium involved chemical reactions.

327 citations


Journal ArticleDOI
TL;DR: In this paper, the authors investigated inorganic clay as a compatibilizer for immiscible poly(propylene)/polystyrene blends and found that a substantial decrease in the number of polystyrene particles was seen after adding small amounts of an organically treated clay (2-5 wt.-%) to the blends.
Abstract: Inorganic clay was investigated as a compatibilizer for immiscible poly(propylene)/polystyrene blends. A substantial decrease in the number of polystyrene particles was seen after adding small amounts of an organically treated clay (2-5 wt.-%) to the blends. A possible mechanism for this kind of compatibilization is discussed, but these unique and completely new findings need further verification.

293 citations


Journal ArticleDOI
J. Z. Bai, Y. Ban1, J. G. Bian, XZ(蔡翔舟) Cai  +195 moreInstitutions (19)
TL;DR: In this paper, the authors observed a narrow enhancement near 2m(p) in the invariant mass spectrum of pp pairs from radiative J/psi-->gammapp decays.
Abstract: We observe a narrow enhancement near 2m(p) in the invariant mass spectrum of pp pairs from radiative J/psi-->gammapp decays. No similar structure is seen in J/psi-->pi(0)pp decays. The results are based on an analysis of a 58 x 10(6) event sample of J/psi decays accumulated with the BESII detector at the Beijing electron-positron collider. The enhancement can be fit with either an S- or P-wave Breit-Wigner resonance function. In the case of the S-wave fit, the peak mass is below 2m(p) at M=1859(+3)(-10) (stat)+5-25(syst) MeV/c(2) and the total width is Gamma<30 MeV/c(2) at the 90% confidence level. These mass and width values are not consistent with the properties of any known particle.

250 citations


Journal ArticleDOI
TL;DR: In this paper, an ultrasonically initiated in situ emulsion polymerization approach was used to modify multi-walled carbon nanotubes (MWCNTs) in aqueous solution under ultrasonic irradiation.
Abstract: In this study, a novel ultrasonically initiated in situ emulsion polymerization approach was used to modify multi-walled carbon nanotubes (MWCNTs). The dispersion behavior of MWCNTs in aqueous solution under ultrasonic irradiation was investigated by spectrophotometry. Ultrasonically initiated emulsion polymerization of monomer n-butyl acrylate (BA) and methyl methacrylate (MMA) are reported. By employing the multiple effects of ultrasound, i.e., dispersion, pulverizing, activation, and initiation, the aggregation and entanglement of carbon nanotubes in aqueous solution can be broken down, while in situ polymerization of monomer BA or MMA on the surface of MWCNTs proceeds without any added chemical initiator; consequently, the MWCNTs are coated by the formed polymer. Transmission electron microscopy confirms that after surface modification through ultrasonically initiated in-situ polymerization, the size of MWCNTs increased; even after 72 h of Soxhlet extraction with boiling acetone there are still unextr...

235 citations


Journal ArticleDOI
TL;DR: The resolvent operator associated with an H-monotone operator is defined and its Lipschitz continuity is presented and a new algorithm for solving this class of variational inclusions by using the resolent operator technique is constructed.

194 citations


Journal ArticleDOI
09 Jan 2003
TL;DR: In this article, the literatures concerning the properties of various blends of starch and aliphatic polyesters have been summarized and the biodegradable rates of blends can be controlled to a certain extent depending on the constitutions of blends, and the mechanical properties of blends are close to those of traditional plastics such as polyethylene and polystyrene.
Abstract: Starch, one of the most inexpensive and most readily available of all natural polymers, can be processed into thermoplastic materials only in the presence of plasticizers and under the action of heat and shear. Poor water resistance and low strength are limiting factors for the use of materials manufactured only from starch, and hence the modification of starch is often achieved by blending aliphatic polyesters. In this review, the literatures concerning the properties of various blends of starch and aliphatic polyesters have been summarized. The biodegradable rates of blends can be controlled to a certain extent depending on the constitutions of blends, and the mechanical properties of blends are close to those of traditional plastics such as polyethylene and polystyrene. The reduction of their sensitivity to humidity makes these materials suitable for the production of biodegradable films, injection-molded items, and foams.

180 citations


Journal ArticleDOI
TL;DR: This article reviews studies on the mechanism, affecting factors, and controlling strategies associated with protein adsorption in blood aphereses and purification procedures.

172 citations


Journal ArticleDOI
Hesheng Xia1, Qi Wang1
TL;DR: In this paper, the stability of colloid dispersion, UV-vis spectra, composition, interaction, conductivity, and other characteristics of polyaniline/nano-SiO2 particle composites were examined.
Abstract: Polyaniline/nano-SiO2 particle composites were prepared through ultrasonic irradiation. Polymerization of aniline was conducted under ultrasonic irradiation in the presence of two types of nano-SiO2: porous nanosilica and spherical nanosilica. The stability of the colloid dispersion, UV–vis spectra, composition, interaction, conductivity, and other characteristics of the composites were examined. It was found that the aggregation of nano-SiO2 could be reduced under ultrasonic irradiation and that nanoparticles were redispersed in the aqueous solution. The formed polyaniline deposited on the surface of the nanoparticle, which led to a core–shell structure. Two particle morphologies, threadlike aggregates with a few spherical nanoparticles for porous nanosilica and spherical particles with a few sandwichlike particles for spherical nanosilica, were observed. X-ray photoelectron spectroscopy showed that for two types of composites the ratio of Si atoms to N atoms (Si:N) on the surface was much higher than that in the bulk. The UV–vis spectra of the diluted colloid dispersion of polyaniline/nano-SiO2 composite particles were similar to those of the polyaniline system. Fourier transform infrared spectroscopy suggested strong interaction between polyaniline and nano-SiO2. The conductivity of the polyaniline/porous nanosilica (23.1 wt % polyaniline) and polyaniline/spherical nanosilica (20.6 wt % polyaniline) composites was 2.9 and 0.2 S/cm, respectively. © 2003 Wiley Periodicals, Inc. J Appl Polym Sci 87: 1811–1817, 2003

160 citations


Journal ArticleDOI
Qiyi Zhang1, Jiyong Chen1, Jiaming Feng1, Yang Cao1, Chunlin Deng1, Xingdong Zhang1 
TL;DR: HA coatings were characterized by X-ray diffraction, scanning electron microscope, and Fourier transform infrared spectra before and after immersion in simulated body fluid (SBF); both dissolution and precipitation occurred at the same time, but the kinetics of dissolution was quite different from that of precipitation.

151 citations


Journal ArticleDOI
TL;DR: In this article, the authors discuss Hyers-Ulam stability for functional equations in single variable, including the forms of linear functional equation, nonlinear functional equation and iterative equation.

Journal Article
TL;DR: Curcin has an obvious antitumor effect and its mechanisms are related to the N-glycosidase activity, and there were relatively high similarities among them.
Abstract: AIM: To study the antitumor effects of curcin from Jatropha curcas. METHODS: Antitumor activity of curcin was tested by MTT assay. The N-glycosidase activity of curcin was determined by characterization of R-fragment in gel. A cell-free system, rabbit reticulocyte lysate, was introduced to quantify the inhibitory activity of curcin on protein biosynthesis. RESULTS: The curcin had a powerful inhibitory action upon protein synthesis in reticulocyte lysate with an IC50 (95 % confidence limits) value of 0.19 (0.11-0.27) nmol/L. The IC50 (95 % confidence limits) of curcin on SGC-7901, Sp2/0, and human hepatoma was 0.23 (0.15-0.32) mg/L, 0.66 (0.35-0.97) mg/L, 3.16 (2.74-3.58) mg/L, respectively. Curcin was found to have no toxic to Hela cells and normal cells (MRC). After the rRNA of ribosome was treated with curcin and aniline at acidic condition, a cleaved R-fragment of approximately 450 nt appeared, but this fragment did not occur after treatment with curcin only. A comparison of the amino acid sequences of curcin, ricin A-chain and trichosanthin revealed that there were relatively high similarities among them. The percentages of homology between curcin and ricin A chain, between curcin and trichosanthin were found to be 54 % and 57 % respectively. Especially, the conserved residues forming the active sites of the A chain of ricin and trichosanthin occurred in curcin. CONCLUSION: Curcin has an obvious antitumor effect and its mechanisms are related to the N-glycosidase activity.

Journal ArticleDOI
TL;DR: In this paper, a novel process was developed to prepare electrically conducting maleic anhydride grafted polypropylene (gPP)/expanded graphite (EG) nanocomposites by solution intercalation.
Abstract: A novel process was developed to prepare electrically conducting maleic anhydride grafted polypropylene (gPP)/expanded graphite (EG) nanocomposites by solution intercalation. The conducting percolation threshold at room temperature (Φc) of the nanocomposites was 0.67 vol %, much lower than that of the conventional conducting composites prepared by melt mixing (Φc = 2.96 vol %). When the EG content was 3.90 vol %, the electrical conductivity (σ) of the former reached 2.49 × 10−3 S/cm, whereas the σ of the latter was only 6.85 × 10−9 S/cm. The TEM, SEM, and optical microscopy observations confirmed that the significant decrease of Φc and the striking increase of σ might be attributable to the formation of an EG/gPP conducting multiple network in the nanocomposites, involving the network composed of particles with a large surface-to-volume ratio and several hundred micrometers in size, and the networks composed of the boards or sheets of graphite with high width-to-thickness ratio and particles of fine microscale or nanoscale sizes. © 2003 Wiley Periodicals, Inc. J Appl Polym Sci 88: 1864–1869, 2003

Journal ArticleDOI
TL;DR: The authors analyze the existence of the equilibrium point and global exponential stability for Hopfield reaction-diffusion neural networks with time-varying delays by means of the topological degree theory and generalized Halanay inequality.
Abstract: The authors analyze the existence of the equilibrium point and global exponential stability for Hopfield reaction-diffusion neural networks with time-varying delays by means of the topological degree theory and generalized Halanay inequality. Since the diffusion phenomena and time delay could not be ignored in neural networks and electric circuits, the model presented here is close to the actual systems, and the sufficient conditions on global exponential stability established in this paper, which are easily verifiable, have a wider adaptive range.

Journal ArticleDOI
01 Sep 2003-Blood
TL;DR: It is found that immunotherapy with qVEGFR was effective at protective and therapeutic antitumor immunity in several solid and hematopoietic tumor models in mice, and may provide a vaccine strategy for cancer therapy through the induction of autoimmunity against the growth factor receptor associated with angiogenesis in a cross-reaction with single xenogeneic homologous protein.

Journal ArticleDOI
TL;DR: The data showed that increased weight bearing significantly increased the contact area, foot length, foot width, and rearfoot width, while it decreased average height, arch height, and arch angle.
Abstract: Knowledge of the plantar foot shape alteration under weight bearing can offer implications for the design and construction of a comfortable and functional foot support. The purpose of this study was to quantify the change in three-dimensional foot shape under different weight-bearing conditions. The plantar foot shapes of 16 normal feet were collected by an impression casting method under three weight-bearing conditions: non-weight bearing, semi-weight bearing, and full-weight bearing. An optical digitizing system was used to capture the three-dimensional plantar surface shape of the foot cast. Measurements and comparisons from the digitized shapes were conducted for the whole foot and regions of the foot. The data showed that increased weight bearing significantly increased the contact area, foot length, foot width, and rearfoot width, while it decreased average height, arch height, and arch angle. Compared with the non-weight-bearing foot shape, the semi-weight-bearing condition would produce increases in the contact area of 35.1% +/- 21.6 %, foot length of 2.7% +/- 1.2%, foot width of 2.9% +/- 2.4%, and rearfoot width of 5.9% +/- 4.8%, and decreases in the arch height of 15.4% +/- 7.8% and arch angle of 21.7% +/- 17.2%. The full-weight-bearing condition would produce increases in the contact area of 60.4% +/- 33.2%, foot length of 3.4% +/- 1.3%, foot width of 6.0% +/- 2.1%, and rearfoot width of 8.7% +/- 4.9%, and decreases in the arch height of 20.0% +/- 9.2% and arch angle of 41.2% +/- 16.2%. The findings may be useful for considering the change of foot shape in the selection of shoe size and shoe or insole design.

Journal ArticleDOI
TL;DR: In this article, the existence of variational-like inequalities with generalized monotone mappings in Banach spaces using the KKM technique was shown. But the results presented in this paper extend and improve the corresponding results of Refs 1-6.
Abstract: In this paper, we introduce two classes of variational-like inequalities with generalized monotone mappings in Banach spaces Using the KKM technique, we obtain the existence of solutions for variational-like inequalities with relaxed η–α monotone mappings in reflexive Banach spaces We present also the solvability of variational-like inequalities with relaxed η–α semimonotone mappings in arbitrary Banach spaces by means of the Kakutani-Fan-Glicksberg fixed-point theorem The results presented in this paper extend and improve the corresponding results of Refs 1–6

Journal ArticleDOI
Xincai Xiao1, Liang-Yin Chu1, Wen-Mei Chen1, Shu Wang1, Yunkun Li1 
TL;DR: In this article, a novel family of monodisperse thermo-sensitive core-shell hydrogel microspheres with high monodispersity and positively thermally-responsive volume phase transition characteristics with tunable swelling kinetics was reported.
Abstract: In this paper, we report on a novel family of monodisperse thermo-sensitive core–shell hydrogel microspheres that is featured with high monodispersity and positively thermo-responsive volume phase transition characteristics with tunable swelling kinetics, i.e., the particle swelling is induced by an increase rather than a decrease in temperature. The microspheres were fabricated in a three-step process. In the first step, monodisperse poly(acrylamide-co-styrene) seeds were prepared by emulsifier-free emulsion polymerization. In the second step, poly(acrylamide) or poly[acrylamide-co-(butyl methacrylate)] shells were fabricated on the microsphere seeds by free radical polymerization. In the third step, the core–shell microspheres with poly- (acrylamide)/poly(acrylic acid) based interpenetrating polymer network (IPN) shells were finished by a method of sequential IPN synthesis. The proposed monodisperse core–shell microspheres provide a new mode of the phase transition behavior for thermo-sensitive “smart” or “intelligent” monodisperse micro-actuators that is highly attractive for targeting drug delivery systems, chemical separations, sensors, and so on.

Journal ArticleDOI
TL;DR: In this paper, the long time behavior of solutions of the system of thermoelasticity of type III in a bounded domain of ℝn (n = 1,2,3) and in the whole space of n is analyzed.
Abstract: This paper is devoted to analyzing the long time behavior of solutions of the system of thermoelasticity of type III in a bounded domain of ℝn (n = 1,2,3) and in the whole space ℝn. For the first case, we introduce a decoupled system that allows to reduce the problem of the asymptotic behavior for the original system to a suitable observability inequality for the Lame system. In this way most of the existing results for the classical system of thermoelasticity are shown to hold for this system too. In particular, we show that: (1) For most domains the energy of the system does not decay uniformly; (2) Under suitable conditions on the domain that may be described in terms of Geometric Optics, the energy of the system decays exponentially; and (3) For most domains in two space dimensions, the energy of smooth solutions decays polynomially. For the problem in the whole space ℝn, first, based on Fourier analysis and Lyapunov's second method, we show that the energy of longitudinal and thermal waves of the system decays as that of the classical heat equation (while that of the transversal wave component is conservative). Then, by means of a careful spectral analysis, we give a sharp description on the decay rate of the high frequency longitudinal and thermal waves of the system.

Journal ArticleDOI
S Luo, X Liu1, S Mu1, S P Tsai1, C P Wen1 
TL;DR: The observation of numerous mesothelioma cases at Da-yao was a unique finding, due mainly to their lifetime exposure to crocidolite asbestos, and the increased awareness and changes in diagnosis over time may also contribute to the increase.
Abstract: Background: Scattered patches of crocidolite, one form of asbestos, were found in the surface soil in the rural county of Da-yao in southwestern China. In 1983, researchers from the West China University of Medical Sciences (WCUMS) discovered that residents of two villages in Da-yao had hyperendemic pleural plaques and excessive numbers of pleural mesotheliomas. Aims: To review and summarise epidemiological studies, along with other relevant data, and to discuss the potential contribution to environmental risk assessment. Methods: This report is based on a review of several clinical/epidemiological studies conducted by WCUMS researchers since 1984, which included one cross sectional medical examination survey, one clinical/pathological analysis of 46 cases of mesothelioma, and three retrospective cohort mortality studies. Additional information acquired from reviewing original data first hand during a personal visit along with an interview of medical specialists from Da-yao County Hospital was also incorporated. Results: The prevalence of pleural plaque was 20% among peasants in Da-yao over 40 years of age in the cross sectional survey. The average number of mesothelioma cases was 6.6 per year in the 1984–95 period and 22 per year in the 1996–99 period, in a population of 68 000. For those mesothelioma cases that were histology confirmed, there were 3.8 cases/year in the first period and 9 cases/year in the second. Of the 2175 peasants in this survey, 16 had asbestosis. Lung cancer deaths were significantly increased in all three cohort studies. The annual mortality rate for mesothelioma was 85 per million, 178 per million, and 365 per million for the three cohort studies, respectively. The higher exposed peasants had a fivefold increased mesothelioma mortality compared to their lower exposed counterparts. There were no cases of mesothelioma in the comparison groups where no crocidolite was known to exist in the environment. In the third cohort study, almost one of five cancer deaths (22%) was from mesothelioma. The ratio of lung cancer to mesothelioma deaths was low for all three studies (1.3, 3.0, and 1.2, respectively). Conclusions: The observation of numerous mesothelioma cases at Da-yao was a unique finding, due mainly to their lifetime exposure to crocidolite asbestos. The finding of cases dying at a younger age and the relatively high ratio of mesothelioma cases to lung cancer could also be another unique result of lifetime environmental exposure to crocidolite asbestos. Although the commercial use of crocidolite has been officially banned since 1984, the incidence of mesothelioma has continued to show a steady increase, particularly among peasants. Since the latency of mesothelioma is approximately 30–40 years, the ban had little effect in the 1990s. The increased awareness and changes in diagnosis over time may also contribute to the increase. Furthermore, exposure to asbestos stoves and walls continued. The government implemented reduction of these exposures. However, from a public health standpoint, the most important issue is the complete avoidance of further exposure to asbestos.

Journal ArticleDOI
TL;DR: An improved neural network model is developed, which combines the adaptive radial basis function (ARBF) network with statistical characteristics of ozone in selected specific areas, and is used to predict the daily maximum ozone concentration level.

Journal ArticleDOI
TL;DR: In this paper, the effect of carbon source (char former/blowing agent ratio) on the flame retardancy and the water resistance of IFR/Polypropylene (PP) blend was investigated.

Journal ArticleDOI
TL;DR: Electrochemical impedance spectroscopy measurement was used to investigate the nucleation and growth of apatite on chemically treated Ti6Al4V immersed in the SBF solution, and the difference between the behaviors of treated and untreated Ti6 Al4V was found.

Journal ArticleDOI
TL;DR: Sophorae flavescentis extract (matrine) may have antiviral activity and positive effects on liver biochemistry in chronic hepatitis B, but the evidence is not sufficient to recommend matrine for routine clinical use due to the generally low methodological quality of the studies.
Abstract: To evaluate the effects of radix Sophorae flavescentis for chronic hepatitis B, a systematic review of randomized clinical trials was conducted. Randomized trials comparing extract of radix Sophorae flavescentis versus placebo, no intervention, non-specific treatment, other active medicines, or interferon for chronic hepatitis B were identified by electronic and manual searches. Trials of Sophorae herb plus other drugs versus other drugs alone were also included. No blinding and language limitations were applied. The methodological quality of trials was assessed by the Jadad scale plus allocation concealment. Meta-analysis was performed where data was available. Twenty-two randomized trials (n = 2409) were included. Methodological quality of the trials was generally low. The combined results showed that matrine (aqueous extract of Sophorae flavescentis) had antiviral activity, positive liver biochemical effects, and improved symptoms and signs compared with non-specific treatment and other herbal medicines. The combination of matrine and interferon-α (IFN-α), thymosin, or basic treatment showed better effects on viral and liver biochemical responses. The antiviral and biochemical responses were not significantly different between matrine and IFN-α. No serious adverse event was reported. Based on the review, Sophorae flavescentis extract (matrine) may have antiviral activity and positive effects on liver biochemistry in chronic hepatitis B. However, the evidence is not sufficient to recommend matrine for routine clinical use due to the generally low methodological quality of the studies. Further rigorous trials are needed.

Journal ArticleDOI
Zhong-Ming Li1, Ming-Bo Yang1, Bang-Hu Xie1, Jian-Min Feng1, Rui Huang1 
TL;DR: In this article, an in-situ microfiber-reinforced composite (MRC) based on polyethylene (terephthalate) (PET) and polyethylenes (PE) was prepared by slit die extrusion followed by hot stretching.
Abstract: An in-situ microfiber-reinforced composite (MRC) based on polyethylene (terephthalate) (PET) and polyethylene (PE) was prepared by slit die extrusion followed by hot stretching. Test specimens were prepared by injection molding at the processing temperature of the PE matrix. At this temperature, far below the melting temperature of PET, the PET phase is solid and able to keep its shape during processing. The morphological characteristics of the dispersed PET phase in the blend, at a fixed weight composition (15:85) of PET and HDPE, were dependent upon the hot stretching ratio. When the hot stretching ratio was increased from 1 (no stretching) to 47.62, the PET particles changed from spheres and ellipsoids to rodlike particles and finally to microfibers. The maximum and average diameters of the PET particles decreased steadily, while the minimum fiber diameter remained constant. The tensile modulus and strength of PET/PE blends were significantly enhanced with increasing hot stretching ratio, indicating that the microfibers have good reinforcement. Ultimate elongation decreased with increasing hot stretching ratio and there was a critical hot stretching ratio above which a ductile-brittle transition occurred.

Journal ArticleDOI
Ru Wang1, Qi Wang1, Li Li1
TL;DR: In this article, the evaporation behavior of water in modified polyvinyl alcohol (PVA) systems with various plasticizers was investigated by using differential scanning calorimetry.
Abstract: Several modified poly(vinyl alcohol) (PVA) systems with various plasticizers were prepared and their melt-processing was successfully realized. This paper focuses on the study of the evaporation behaviour of water in these modified PVA systems, exploring its plasticizing mechanism by using differential scanning calorimetry. The evaporation characteristics of bulk water, water in aqueous solutions of the plasticizers, and the thermal properties of PVA were also studied. The experimental results show that water in aqueous solutions of glycerol and/or caprolactam evaporates at a lower temperature than bulk water, but water in the PVA/water system evaporates at a higher temperature, with a wider DSC peak due to the interaction between water and PVA. Incorporation of glycerol, caprolactam or their mixtures further strengthens the interactions between water and the other components, retarding water evaporation. During the processing, the less closely associated water has the plasticizing effect through molecule movement, while the strongly bound water, which breaks the intermolecular hydrogen bonding of PVA and decreases its intermolecular interaction, is more beneficial to the melt-processing of PVA. Copyright © 2003 Society of Chemical Industry

Journal ArticleDOI
TL;DR: The results suggest that these types of chimeric peptides may be of value as antibiotics against specific bacterial infections.
Abstract: We constructed a peptide consisting of a staphylococcal AgrD1 pheromone fused to the channel-forming domain of colicin Ia and named it pheromonicin. This fusion peptide had bactericidal effects against methicillin-sensitive and methicillin-resistant Staphylococcus aureus (MSSA and MRSA, respectively), but not against Staphylococcus epidermidis or Streptococcus pneumoniae. Growth rates, vital staining and colony forming unit (CFU) counts showed that pheromonicin did not merely suppress growth but killed S. aureus cells. The specificity of pheromonicin was shown by the absence of bactericidal effects against an accessory gene regulator (agr) locus knockout of S. aureus, and a dose-dependent inhibition of the bactericidal effects of pheromonicin by competition with corresponding free AgrD pheromone. In vivo, all pheromonicin-treated mice survived administration of MRSA that was lethal to controls. No toxicity was detectable in human liver or renal cells in culture, or in livers, kidneys or spleens of pheromonicin-treated mice. The results suggest that these types of chimeric peptides may be of value as antibiotics against specific bacterial infections.

Journal ArticleDOI
TL;DR: It is shown here that vaccination with Xenopus FGFR-1 (pxFR1) is effective at antitumor immunity in three murine models, and may provide a new vaccine strategy for cancer therapy through the induction of autoimmunity against FG FR-1 associated with angiogenesis in a cross-reaction.

Journal ArticleDOI
TL;DR: The evidence from single diffraction patterns indicates that apatite formation on bioactive ceramics is a complicated process, particularly in physiological environments where formation might include a transient stage of intermediate phases.

Journal ArticleDOI
TL;DR: A kind of synthesized thermotropic liquid crystal copolyester containing phosphorus (PLCP) with high flame retardancy (oxygen index, 70%) has been used to prepare in situ reinforced PET composites that have both good flame retardant and better mechanical properties than pure PET as mentioned in this paper.
Abstract: A kind of synthesized thermotropic liquid crystal copolyester containing phosphorus (PLCP) with high flame retardancy (oxygen index, 70%) has been used to prepare in situ reinforced PET composites that have both good flame retardancy and better mechanical properties than pure PET. The melt dripping behavior of PET was also improved.