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Institution

Siddaganga Institute of Technology

About: Siddaganga Institute of Technology is a based out in . It is known for research contribution in the topics: Ultimate tensile strength & Microstructure. The organization has 1349 authors who have published 1373 publications receiving 10940 citations.


Papers
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Journal ArticleDOI
TL;DR: In this paper, a review of the development in TiO2 nanostructured materials for visible-light driven photocatalysis is presented, and the effects of various parameters on their photocatalytic efficiency, photodegradation of various organic contaminants present in wastewater, and photocatalyst disinfection are delineated.

420 citations

Journal ArticleDOI
TL;DR: In this paper, a green synthesis of ZnO nanoparticles (Nps) using aqueous Cassia fistula plant extract as fuel by solution combustion synthesis was reported. But the NPs were evaluated for photodegradative, antimicrobial and antioxidant activities.

389 citations

Journal ArticleDOI
TL;DR: A range of nanomaterials which are currently being employed for anticancer therapies are summarized and the fundamental role of their physicochemical properties in cancer management is discussed to provide an outlook on the future of this important field.
Abstract: Nanotechnology has the potential to circumvent several drawbacks of conventional therapeutic formulations. In fact, significant strides have been made towards the application of engineered nanomaterials for the treatment of cancer with high specificity, sensitivity and efficacy. Tailor-made nanomaterials functionalized with specific ligands can target cancer cells in a predictable manner and deliver encapsulated payloads effectively. Moreover, nanomaterials can also be designed for increased drug loading, improved half-life in the body, controlled release, and selective distribution by modifying their composition, size, morphology, and surface chemistry. To date, polymeric nanomaterials, metallic nanoparticles, carbon-based materials, liposomes, and dendrimers have been developed as smart drug delivery systems for cancer treatment, demonstrating enhanced pharmacokinetic and pharmacodynamic profiles over conventional formulations due to their nanoscale size and unique physicochemical characteristics. The data present in the literature suggest that nanotechnology will provide next-generation platforms for cancer management and anticancer therapy. Therefore, in this critical review, we summarize a range of nanomaterials which are currently being employed for anticancer therapies and discuss the fundamental role of their physicochemical properties in cancer management. We further elaborate on the topical progress made to date toward nanomaterial engineering for cancer therapy, including current strategies for drug targeting and release for efficient cancer administration. We also discuss issues of nanotoxicity, which is an often-neglected feature of nanotechnology. Finally, we attempt to summarize the current challenges in nanotherapeutics and provide an outlook on the future of this important field.

385 citations

Journal ArticleDOI
TL;DR: Current knowledge of articulate engineering of nanomaterials for biomedical applications with special attention on potential toxicological perspectives is explored, which is gaining considerable attention and the field of nanotoxicology is evolving promptly.
Abstract: Innovative engineered nanomaterials are at the leading edge of rapidly emerging fields of nanobiotechnology and nanomedicine. Meticulous synthesis, unique physicochemical properties, manifestation of chemical or biological moieties on the surface of materials make engineered nanostructures suitable for a variety of biomedical applications. Besides, tailored nanomaterials exhibit entirely novel therapeutic applications with better functionality, sensitivity, efficiency and specificity due to their customized unique physicochemical and surface properties. Additionally, such designer made nanomaterials has potential to generate series of interactions with various biological entities including DNA, proteins, membranes, cells and organelles at nano-bio interface. These nano-bio interactions are driven by colloidal forces and predominantly depend on the dynamic physicochemical and surface properties of nanomaterials. Nevertheless, recent development and atomic scale tailoring of various physical, chemical and surface properties of nanomaterials is promising to dictate their interaction in anticipated manner with biological entities for biomedical applications. As a result, rationally designed nanomaterials are in extensive demand for bio-molecular detection and diagnostics, therapeutics, drug and gene delivery, fluorescent labelling, tissue engineering, biochemical sensing and other pharmaceuticals applications. However, toxicity and risk associated with engineered nanomaterials is rather unclear or not well understood; which is gaining considerable attention and the field of nanotoxicology is evolving promptly. Therefore, this review explores current knowledge of articulate engineering of nanomaterials for biomedical applications with special attention on potential toxicological perspectives.

261 citations

Journal ArticleDOI
TL;DR: In this paper, the results reveal that Ag-ZnO Nps shows the better photocatalytic activity compared to undoped ZnO nps, and also developed sensor which showed a linearity in the concentration range 50-350 nM and limit of detection was found to be 3.5 and 3.8 nM (3σ) for lead and cadmium respectively.

258 citations


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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20229
2021234
2020171
2019155
2018140
2017192