SINTEF

Abstract: Agile software development represents a major departure from traditional, plan-based approaches to software engineering. A systematic review of empirical studies of agile software development up to and including 2005 was conducted. The search strategy identified 1996 studies, of which 36 were identified as empirical studies. The studies were grouped into four themes: introduction and adoption, human and social factors, perceptions on agile methods, and comparative studies. The review investigates what is currently known about the benefits and limitations of, and the strength of evidence for, agile methods. Implications for research and practice are presented. The main implication for research is a need for more and better empirical studies of agile software development within a common research agenda. For the industrial readership, the review provides a map of findings, according to topic, that can be compared for relevance to their own settings and situations.

Abstract: Summary Background A randomised double-blind placebo-controlled phase II study was done to assess the efficacy of a prophylactic quadrivalent vaccine targeting the human papillomavirus (HPV) types associated with 70% of cervical cancers (types 16 and 18) and with 90% of genital warts (types 6 and 11). Methods 277 young women (mean age 20·2 years [SD 1·7]) were randomly assigned to quadrivalent HPV (20 μg type 6, 40 μg type 11, 40 μg type 16, and 20 μg type 18) L1 virus-like-particle (VLP) vaccine and 275 (mean age 20·0 years [1·7]) to one of two placebo preparations at day 1, month 2, and month 6. For 36 months, participants underwent regular gynaecological examinations, cervicovaginal sampling for HPV DNA, testing for serum antibodies to HPV, and Pap testing. The primary endpoint was the combined incidence of infection with HPV 6, 11, 16, or 18, or cervical or external genital disease (ie, persistent HPV infection, HPV detection at the last recorded visit, cervical intraepithelial neoplasia, cervical cancer, or external genital lesions caused by the HPV types in the vaccine). Main analyses were done per protocol. Findings Combined incidence of persistent infection or disease with HPV 6, 11, 16, or 18 fell by 90% (95% CI 71–97, p Interpretation A vaccine targeting HPV types 6, 11, 16, 18 could substantially reduce the acquisition of infection and clinical disease caused by common HPV types. Published online April 7, 2005 DOI 10.1016/S1470-2045(05)70101-7

Abstract: The Atomic Simulation Environment (ASE) is a software package written in the Python programming language with the aim of setting up, steering, and analyzing atomistic simula- tions. In ASE, tasks are fully scripted in Python. The powerful syntax of Python combined with the NumPy array library make it possible to perform very complex simulation tasks. For example, a sequence of calculations may be performed with the use of a simple "for-loop" construction. Calculations of energy, forces, stresses and other quantities are performed through interfaces to many external electronic structure codes or force fields using a uniform interface. On top of this calculator interface, ASE provides modules for performing many standard simulation tasks such as structure optimization, molecular dynamics, handling of constraints and performing nudged elastic band calculations.

Abstract: In this review, we summarize the knowledge of the production and properties of charcoal that has been accumulated over the past 38 millenia. The manipulation of pressure, moisture content, and gas flow enables biomass carbonization with fixed-carbon yields that approachor attainthe theoretical limit after reaction times of a few tens of minutes. Much of the heat needed to carbonize the feed is released by vigorous, exothermic secondary reactions that reduce the formation of unwanted tars by augmenting the charcoal yield in a well-designed carbonizer. As a renewable fuel, charcoal has many attractive features: it contains virtually no sulfur or mercury and is low in nitrogen and ash; it is highly reactive yet easy to store and handle. Carbonized charcoal can be a good adsorbent with a large surface area and a semimetal with an electrical resistivity comparable to that of graphite. Recent advances in knowledge about the production and properties of charcoal presage its expanded use as a renewable fuel, red...

Abstract: The literature related to methanol-to-hydrocarbons (MTHC) technology over the past two decades has been reviewed, covering mainly the methanol-to-olefin (MTO) and methanol-to-gasoline (MTG) reactions. The work before around 1990 is briefly addressed, and the interested reader's attention is drawn to review papers published during the late 1980s summarizing the early work related to the methanol-to-hydrocarbons technology. This review focuses mainly on the chemistry and mechanism of those reactions including the catalysts involved and their behavior due to crystal size, pore architecture, acidity and reaction conditions, covering the time since around 1990. In a second review authored by F. Keil, the process related items of methanol-to-hydrocarbons technology will be summarized and discussed in the light of kinetic and reaction technology aspects.