SNDT Women's University

About: SNDT Women's University is a education organization based out in Mumbai, Maharashtra, India. It is known for research contribution in the topics: Routing protocol & Femtocell. The organization has 252 authors who have published 260 publications receiving 2609 citations. The organization is also known as: Shreemati Nathibai Damodar Thackersey Women's University.

Evaluation of phytoconstituents of Terminalia arjuna for wound healing activity in rats

Abstract: The effect of topical application of phytoconstituents (fraction I, II and III) fractionated from a hydroalcohol extract of the bark of the plant, Terminalia arjuna, was assessed on the healing of rat dermal wounds using in vivo models The results indicated a statistically significant increase in the tensile strength of the incision wounds and the percent epithelialization of excision wounds compared with control (p < 005) However, topical treatment with fraction I, consisting mainly of tannins, was found to demonstrate a maximum increase in the tensile strength of incision wounds Even with respect to excision wounds, the fastest rate of epithelialization was seen with fraction I Hexosamine estimation of granulation tissue obtained from excision wounds revealed an increase in the hexosamine content with fraction I compared with the control In addition, fraction I from the hydroalcohol extract of Arjuna bark possessed antimicrobial activity against tested microorganisms such as Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, Streptococcus pyogenes but not Candida albicans These results strongly document the beneficial effects of fraction I, consisting mainly of tannins, of Terminalia arjuna in the acceleration of the healing process Thus, the present study validates the claim made with respect to the plant as well as corroborating the astringent effect of tannins by drawing the tissues closer together

Evaluation of the immunomodulatory activity of the methanol extract of Ficus benghalensis roots in rats

Abstract: Objective: To evaluate the immunomodulatory activity of the aerial roots of Ficus benghalensis (Family Moraceae). Materials and Methods: Various extracts of the aerial roots of Ficus benghalensis were evaluated for potential immunomodulatory activity, using the in vitro polymorphonuclear leucocyte (human neutrophils) function test. The methanol extract was evaluated for immunomodulatory activity in in vivo studies, using rats as the animal model. The extracts were tested for hypersensitivity and hemagglutination reactions, using sheep red blood cells (SRBC) as the antigen. Distilled water served as a control in all the tests. Results: The successive methanol and water extracts exhibited a significant increase in the percentage phagocytosis versus the control. In the in vivo studies, the successive methanol extract was found to exhibit a dose related increase in the hypersensitivity reaction, to the SRBC antigen, at concentrations of 100 and 200 mg/kg. It also resulted in a significant increase in the antibody titer value, to SRBC, at doses of 100 and 200 mg/kg in animal studies. Conclusion: The successive methanol extract was found to stimulate cell mediated and antibody mediated immune responses in rats. It also enhanced the phagocytic function of the human neutrophils, in vitro.

Colostrum - Its Composition, Benefits As A Nutraceutical : A Review

Abstract: Colostrumis ‘the first milk secreted at the time of parturition, differing from the milk secreted later, by containing more lactalbumin and lactoprotein, and also being rich in antibodies that confer passive immunity to the newborn, also called “foremilk”. Human Colostrum (HC) and Bovine Colostrum (BC) are rich in protein, immunoglobulin, lactoferrin and growth factors. Recent studies suggest that colostrum components, immunoglobulin and growth factor benefits physically active personandin treatment of autoimmune disorders. It is used for the treatment of a wide variety of gastrointestinal conditions, including non-steroidal anti-inflammatory drug–induced gut injury, H pylori infection, immune deficiency related diarrhea as well as infective diarrhea. This review explores the current knowledge on the beneficial effect of colostrum supplementation in the above condition.