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Showing papers by "Sofia University published in 2008"


Journal ArticleDOI
TL;DR: The Compact Muon Solenoid (CMS) detector at the Large Hadron Collider (LHC) at CERN as mentioned in this paper was designed to study proton-proton (and lead-lead) collisions at a centre-of-mass energy of 14 TeV (5.5 TeV nucleon-nucleon) and at luminosities up to 10(34)cm(-2)s(-1)
Abstract: The Compact Muon Solenoid (CMS) detector is described. The detector operates at the Large Hadron Collider (LHC) at CERN. It was conceived to study proton-proton (and lead-lead) collisions at a centre-of-mass energy of 14 TeV (5.5 TeV nucleon-nucleon) and at luminosities up to 10(34)cm(-2)s(-1) (10(27)cm(-2)s(-1)). At the core of the CMS detector sits a high-magnetic-field and large-bore superconducting solenoid surrounding an all-silicon pixel and strip tracker, a lead-tungstate scintillating-crystals electromagnetic calorimeter, and a brass-scintillator sampling hadron calorimeter. The iron yoke of the flux-return is instrumented with four stations of muon detectors covering most of the 4 pi solid angle. Forward sampling calorimeters extend the pseudo-rapidity coverage to high values (vertical bar eta vertical bar <= 5) assuring very good hermeticity. The overall dimensions of the CMS detector are a length of 21.6 m, a diameter of 14.6 m and a total weight of 12500 t.

5,193 citations


Journal ArticleDOI
TL;DR: The hypothesis for some exceptionally high coalescence stability of the particle-stabilized emulsions is not supported by the experimental data available in literature, and the particles are able to completely arrest the process of Ostwald ripening in foams and emulsion.
Abstract: The aim of this paper is to present a short overview of the main mechanisms operative in the formation and stabilization of emulsions by solid particles and, on this basis, to make comparisons between solid particles, surfactants and globular proteins as emulsifiers. When available, simple quantitative relations are presented, with the respective numerical estimates and discussion of the applicability of these relations to particle-stabilized systems. Non-obvious similarities between the different types of emulsifiers are outlined in several cases in which the description of the system can be performed at a phenomenological level. Examples are presented for the process of emulsification, where we show that several simple theoretical expressions, derived originally in the studies of surfactants and protein emulsifiers, can be successfully applied to particle-stabilized emulsions. In contrast, for the phenomena in which the detailed mechanisms of particle adsorption and film stabilization are important, the differences between the various emulsifiers prevail, thus making it impossible to use the same theoretical description. The most important specific characteristics of the solid particles which strongly affect their behavior are the high barrier to particle adsorption, high desorption energy and strong capillary forces between particles trapped in liquid films, which all originate in the relatively large particle size (as compared to the size of surfactant and protein molecules). The capillary mechanism of stabilization of liquid films by solid particles is reviewed in some detail, to emphasize its specific features and to demonstrate the applicability of several simple expressions for approximate estimates. Interestingly, we found that the hypothesis for some exceptionally high coalescence stability of the particle-stabilized emulsions is not supported by the experimental data available in literature. On the other hand, the particles are able to completely arrest the process of Ostwald ripening in foams and emulsions, and this effect can be easily explained with the high desorption energy of the particles and the resulting capillary effects.

423 citations


Journal ArticleDOI
TL;DR: In this article, the authors compare three spectral synthesis models for single stellar populations (SSPs): Pegase-HR, Galaxev and Vazdekis/Miles, and analyse spectra of Galactic clusters whose populations are known from studies of colour-magnitude diagrams (CMD) and spectroscopy of individual stars.
Abstract: Fitting whole spectra at intermediate spectral resolution (R= 1000–3000), to derive physical properties of stellar populations, appears as an optimized alternative to methods based on spectrophotometric indices: it uses all the redundant information contained in the signal. This paper addresses the validation of the method and it investigates the quality of the population models together with the reliability of the fitting procedures. Our method compares observed optical spectra with models to derive the age, metallicity and line broadening due to the internal kinematics. It is insensitive to the shape of the continuum and the results are consistent with Lick indices but three times more precise. We are using two algorithms: steckmap, a non-parametric regularized program and nbursts a parametric non-linear minimization. We compare three spectral synthesis models for single stellar populations (SSPs): Pegase-HR, Galaxev and Vazdekis/Miles, and we analyse spectra of Galactic clusters whose populations are known from studies of colour–magnitude diagrams (CMD) and spectroscopy of individual stars. We find the following. (1) The quality of the models critically depends on the stellar library they use, and in particular on its coverage in age, metallicity and surface gravity of the stars. Pegase-HR and Vazdekis/Miles are consistent, while the comparison between Pegase-HR and Bruzual & Charlot shows some systematics reflecting the limitations of the stellar library (STELIB) used to generate the latter models. (2) The two fitting programs are consistent. (3) For globular clusters and M67 spectra, the method restitutes metallicities in agreement with spectroscopy of stars with a precision of 0.14 dex. (4) The spectroscopic ages are very sensitive to the presence of a blue horizontal branch (BHB) or of blue stragglers. A BHB morphology results in a young SSP-equivalent age. Fitting a free amount of blue stars in addition to the SSP model to mimic the BHB improves and stabilizes the fit and restores ages in agreement with CMDs studies. This method is potentially able to disentangle age or BHB effects in extragalactic clusters. Full spectrum fitting is reliable method to derive the parameters of a stellar population.

200 citations


Journal ArticleDOI
TL;DR: In this article, it was shown that two stationary, asymptotically flat vacuum black holes in 5 dimensions with two commuting axial symmetries are identical if and only if their masses, angular momenta, and their "interval structures" coincide.
Abstract: We show that two stationary, asymptotically flat vacuum black holes in 5 dimensions with two commuting axial symmetries are identical if and only if their masses, angular momenta, and their “interval structures” coincide. We also show that the horizon must be topologically either a 3-sphere, a ring, or a Lens-space. Our argument is a generalization of constructions of Morisawa and Ida (based in turn on key work of Maison) who considered the spherical case, combined with basic arguments concerning the nature of the factor manifold of symmetry orbits.

195 citations


Journal ArticleDOI
13 Aug 2008-Langmuir
TL;DR: A new class of surfactant mixtures is described, which is particularly suitable for studies related to foam dynamics, such as studies of foam rheology, liquid drainage from foams and foam films, and bubble coarsening and rearrangement.
Abstract: A new class of surfactant mixtures is described, which is particularly suitable for studies related to foam dynamics, such as studies of foam rheology, liquid drainage from foams and foam films, and bubble coarsening and rearrangement. These mixtures contain an anionic surfactant, a zwitterionic surfactant, and fatty acids (e.g., myristic or lauric) of low concentration. Solutions of these surfactant mixtures exhibit Newtonian behavior, and their viscosity could be varied by using glycerol. Most importantly, the dynamic surface properties of these solutions, such as their surface dilatational modulus, strongly depend on the presence and on the chain-length of fatty acid(s). Illustrative results are shown to demonstrate the dependence of solution properties on the composition of the surfactant mixture, and the resulting effects on foam rheological properties, foam film drainage, and bubble Ostwald ripening. The observed high surface modulus in the presence of fatty acids is explained with the formation of a surface condensed phase of fatty acid molecules in the surfactant adsorption layer.

158 citations


Journal ArticleDOI
TL;DR: It was established that the major part of arsenic and lead in herbal infusions existed in biomacromolecular fraction.

145 citations


Journal ArticleDOI
TL;DR: An overview of the impact of age on human immune competence is provided, emphasizing T-cell-dependent adaptive immunity, which is the most sensitive to ageing, and will pave the way for rational interventions to maintain or restore appropriate immune function not only in the elderly but also in the cancer patient.
Abstract: Compromised immunity contributes to the decreased ability of the elderly to control infectious disease and to their generally poor response to vaccination. It is controversial as to how far this phenomenon contributes to the well-known age-associated increase in the occurrence of many cancers in the elderly. However, should the immune system be important in controlling cancer, for which there is a great deal of evidence, it is logical to propose that dysfunctional immunity in the elderly would contribute to compromised immunosurveillance and increased cancer occurrence. The chronological age at which immunosenescence becomes clinically important is known to be influenced by many factors, including the pathogen load to which individuals are exposed throughout life. It is proposed here that the cancer antigen load may have a similar effect on "immune exhaustion" and that pathogen load and tumor load may act additively to accelerate immunosenescence. Understanding how and why immune responsiveness changes in humans as they age is essential for developing strategies to prevent or restore dysregulated immunity and assure healthy longevity, clearly possible only if cancer is avoided. Here, we provide an overview of the impact of age on human immune competence, emphasizing T-cell-dependent adaptive immunity, which is the most sensitive to ageing. This knowledge will pave the way for rational interventions to maintain or restore appropriate immune function not only in the elderly but also in the cancer patient.

139 citations


Journal ArticleDOI
TL;DR: Rehospitalization reflects the chronic course in a sizable proportion of adolescent patients with anorexia nervosa and family psychopathology may have an effect both in terms of genetic vulnerability and environmental stress leading to unfavorable courses.
Abstract: OBJECTIVE: The course and clinical predictors of rehospitalization were studied in a large sample of adolescent patients with anorexia nervosa who had been treated at five European sites and been followed-up. METHOD: Two-hundred and twelve adolescent patients first admitted for in-patient treatment, aged 10-18 (Mean 14.9) years and 94.8% female, were followed-up for an average of 8.3 years after first admission at sites in (former East and West Berlin, Zurich, Sofia, and Bucharest). Clinical history data were collected by use of standardized item-sheets at first admission. Semi-structured interviews including ratings of eating pathology and psychosocial outcome were performed at follow-up. RESULTS: About 44.8% (95/212) of the patients required at least one readmission. Rates of rehospitalization were significantly higher at the Eastern sites (Sofia and Bucharest). Significant predictors of readmission were paternal alcoholism, history of anorexia nervosa in the family, eating disorder in infancy, periodic overactivity, lower weight increase at first admission, and lower BMI at first discharge. In a model of logistic regression analysis, five variables (paternal alcoholism, eating disorder in infancy, periodic overactivity, low weight increase during first admission, and low BMI at first discharge) correctly classified 69% of the participants into cases with single or repeated admissions. Patients with repeated admissions had a less favorable long term outcome and had higher rates of persisting psychopathology at follow-up. CONCLUSION: Rehospitalization reflects the chronic course in a sizable proportion of adolescent patients with anorexia nervosa. Family psychopathology may have an effect both in terms of genetic vulnerability and environmental stress leading to unfavorable courses. The strong effect of insufficient weight gain during first admission and lower BMI at first discharge emphasizes the importance of adequate interventions. Readmissions carry the risk for later poor psychosocial and psychiatric outcomes. © 2007 by Wiley Periodicals, Inc. Int J Eat Disord 2008

137 citations


Journal ArticleDOI
TL;DR: The difference in prevalence of depressive symptoms in university students from Eastern and Western European countries persists 15 years after political changes have taken place and cannot be explained by differences in perceived sufficiency of income.
Abstract: Previous research indicated a higher prevalence of depressive symptoms among students from Eastern European countries than students from Western European countries. This difference was thought to be linked to political and economic instabilities resulting from political changes in the early 1990s. We investigated whether these differences persist 15 years later. Using data from a general health survey among first year students (N = 2,651) from two Western (Germany and Denmark) and two Eastern European countries (Poland and Bulgaria), our analysis was restricted to 2,146 students below 23 years of age. Depressive symptoms were measured using the Modified Beck Depression Inventory (M-BDI). The recommended cut-off point of the M-BDI for depression screening in the general population is a score of ≥35. Perceived income sufficiency was measured on a four-point scale from “totally sufficient” to “not sufficient at all”. Analysis of variance and logistic regression were performed to assess the differences in depressive symptoms between countries adjusting for income sufficiency. Depressive symptoms were more prevalent in Eastern European than Western European countries (M-BDI scores of ≥35 in Germany 26.7%/22.8%, in Denmark 24.9%/12.1%, in Poland 45.5%/27.3%, in Bulgaria 42.9%/33.8% for female and male students, respectively). There was an association between income perceived as insufficient and higher levels of depressive symptoms, but it did not differ across the countries. Adjusting for perceived income sufficiency had little effect on differences in the prevalence of depressive symptoms across countries. The difference in prevalence of depressive symptoms in university students from Eastern and Western European countries persists 15 years after political changes have taken place and cannot be explained by differences in perceived sufficiency of income.

133 citations


Journal ArticleDOI
TL;DR: It is shown that the conical beams are formed as a result of the higher-order nonlinear Bragg diffraction involving two parametric processes in which an ordinary fundamental wave is converted simultaneously into ordinary and extraordinary polarized second harmonics.
Abstract: We report on the observation of second-harmonic conical waves generated in a novel geometry of the transverse excitation of an annular periodically poled nonlinear photonic structure by a fundamental Gaussian beam. We show that the conical beams are formed as a result of the higher-order nonlinear Bragg diffraction involving two parametric processes in which an ordinary fundamental wave is converted simultaneously into ordinary and extraordinary polarized second harmonics.

130 citations


Journal ArticleDOI
TL;DR: It is demonstrated that the release of As(V) and/or As(III), together with the bio-reduction of As-V and the subsequent methylation of As (III) may be a detoxification mechanism for these algae.

Journal ArticleDOI
TL;DR: Psychosomatic complaints were the most important indicators in forming a rating frame for students' self-rated health status, and the results suggest that SRHS can be reasonably used to compare students' health across countries.
Abstract: Self-rated health status (SRHS) is a reliable and valid measure for assessing the subjective and objective health of individuals. Previous studies have either focused predominantly on the elderly or investigated only a narrow range of factors potentially associated with SRHS. In examining student populations, these past studies were limited to single countries. The objectives of this study were to assess which candidate variables were independently associated with SRHS in university students, to compare these variables by country and by gender, and to investigate which of the variables was most important as a rating frame for SRHS. The data is from the Cross-National Student Health Survey, conducted in 2005 in universities in Germany, Bulgaria, and Poland (n = 2103; mean age = 20.7 years). SRHS was assessed with a single question using a five-point scale ranging from "excellent" to "poor". The study also measured a wide range of variables including: physical and psychological health, studying, social contacts/social support, and socio-demographic status. Psychosomatic complaints (considered an aspect of physical health and, adjusted for psychological health) were the most important indicators in forming a rating frame for students' SRHS. There were few differences in the effects of variables associated with SRHS by gender (well-being: a measure of psychological health) and the variables associated with SRHS by country (well-being and self-efficacy). The remaining variables showed homogenous effects for both genders and for all three countries. The results suggest that SRHS can be reasonably used to compare students' health across countries. SRHS is affected by different physical, psychological and psychosomatic aspects of health; however, its strongest association is with psychosomatic complaints.

Journal ArticleDOI
TL;DR: In this article, the authors model massive compact objects in galactic nuclei as stationary, axially symmetric naked singularities in the Einstein-massless scalar field theory and study the resulting gravitational lensing.
Abstract: We model massive compact objects in galactic nuclei as stationary, axially symmetric naked singularities in the Einstein-massless scalar field theory and study the resulting gravitational lensing. In the weak deflection limit we study analytically the position of the two weak field images, the corresponding signed and absolute magnifications as well as the centroid up to post-Newtonian order. We show that there are static post-Newtonian corrections to the signed magnification and their sum as well as to the critical curves, which are functions of the scalar charge. The shift of the critical curves as a function of the lens angular momentum is found, and it is shown that they decrease slightly for the weakly naked and vastly for the strongly naked singularities with the increase of the scalar charge. The pointlike caustics drift away from the optical axis and do not depend on the scalar charge. In the strong deflection limit approximation, we compute numerically the position of the relativistic images and their separability for weakly naked singularities. All of the lensing quantities are compared to particular cases as Schwarzschild and Kerr black holes as well as Janis-Newman-Winicour naked singularities.

Journal ArticleDOI
C. Alt1, Katarzyna Grebieszkow2, I. K. Yoo3, W. Peryt2, E. Gladysz4, V. Eckardt5, B. Lungwitz1, Z. Fodor6, N. Schmitz5, J. Sziklai7, J. Bartke4, P. Chung8, Kreso Kadija, V. Friese9, Ferenc Sikler7, P. Csato7, M. Utvić1, M. Słodkowski2, Zbigniew Wlodarczyk, M. Vassiliou10, Helena Bialkowska, C. Strabel1, Andras Laszlo7, G. L. Melkumov11, V. I. Kolesnikov11, Maciej Rybczyński, Christoph Blume1, J. G. Cramer12, Apostolos Panagiotou10, J. Pluta2, M. Szuba2, G. Stefanek, D. Barna7, M. van Leeuwen, D. Vranic9, A. Richard1, I. Kraus9, O. Chvala13, Gunther Roland14, C. Höhne9, J. Gál7, S. Hegyi7, M. Makariev15, Andre Mischke, Andreas Petridis10, G. Pálla7, M. Botje, M. K. Mitrovski1, Mrowczynski15, Panagiota Foka9, P. Dinkelaker1, B. Baatar11, Marek Kowalski4, S. Kniege1, P. Christakoglou10, Leander Litov15, R. Bramm1, Peter Levai7, E. Skrzypczak16, M. Gazdzicki10, E. Kornas4, Branislav Sitar17, T. Susa, T. Antičić, D. Flierl1, R. Lacey8, Andrzej Rybicki4, Latchezar Betev18, H. Ströbele1, Miroslav Pikna17, V. Genchev19, Jozsef Molnar7, I. Szentpetery7, M. Mateev15, F. Pühlhofer20, P. Szymanski18, Alexander Malakhov11, V. Trubnikov, Michal Kreps17, Rainer Arno Ernst Renfordt1, J. Zimányi7, D. J. Prindle12, Predrag Buncic18, T. R. Schuster1, V. Cerny17, A. Karev5, Bożena Boimska, M. Kliemant1, D. P. Kikola2, Dezso Varga7, A. Wojtaszek, P. Seyboth5, R. Stock1, V. Nicolic, C. Meurer1, Gabor Istvan Veres7, Gabor Istvan Veres14, Gyorgy Vesztergombi7, J. Bracinik17, D. Panayotov15, A. Sandoval9, A. Wetzler1, Christof Roland14 
TL;DR: In this paper, the energy dependence of transverse mass spectra, rapidity spectra and multiplicities is discussed and comparisons to string hadronic models (UrQMD and HSD) and statistical hadron gas models are shown.
Abstract: Results on {lambda},{lambda},{xi}{sup -}, and {xi}{sup +} production in central Pb+Pb reactions at 20A,30A,40A,80A, and 158A GeV are presented. The energy dependence of transverse mass spectra, rapidity spectra, and multiplicities is discussed. Comparisons to string hadronic models (UrQMD and HSD) and statistical hadron gas models are shown. Although the latter provide a reasonable description of all particle yields, the first class of models fails to match the {xi}{sup -} and {xi}{sup +} multiplicities.

Journal ArticleDOI
TL;DR: In this paper, the authors present and analyse the WEBT multifrequency observations of 3C 454.3 in the 2007-2008 observing season, including XMM-Newton observations and near-IR spectroscopic monitoring, and compare the recent emission behaviour with the past one.
Abstract: We present and analyse the WEBT multifrequency observations of 3C 454.3 in the 2007-2008 observing season, including XMM-Newton observations and near-IR spectroscopic monitoring, and compare the recent emission behaviour with the past one. In the optical band we observed a multi-peak outburst in July-August 2007, and other faster events in November 2007 - February 2008. During these outburst phases, several episodes of intranight variability were detected. A mm outburst was observed starting from mid 2007, whose rising phase was contemporaneous to the optical brightening. A slower flux increase also affected the higher radio frequencies, the flux enhancement disappearing below 8 GHz. The analysis of the optical-radio correlation and time delays, as well as the behaviour of the mm light curve, confirm our previous predictions, suggesting that changes in the jet orientation likely occurred in the last few years. The historical multiwavelength behaviour indicates that a significant variation in the viewing angle may have happened around year 2000. Colour analysis reveals a complex spectral behaviour, which is due to the interplay of different emission components. All the near-IR spectra show a prominent Halpha emission line, whose flux appears nearly constant. The analysis of the XMM-Newton data indicates a correlation between the UV excess and the soft-X-ray excess, which may represent the head and the tail of the big blue bump, respectively. The X-ray flux correlates with the optical flux, suggesting that in the inverse-Compton process either the seed photons are synchrotron photons at IR-optical frequencies or the relativistic electrons are those that produce the optical synchrotron emission. The X-ray radiation would thus be produced in the jet region from where the IR-optical emission comes.

Journal ArticleDOI
TL;DR: Chronic ingestion of a Mediterranean diet avoids the postprandial deterioration of endothelial function associated with Westernised diets in healthy individuals.
Abstract: Traditional cardiovascular risk factors are associated with endothelial dysfunction. The vascular endothelium plays a key role in local vascular tone regulation and can be modulated by dietary fat. We propose to determine the chronic effect of three diets with different fat compositions on postprandial endothelial function and inflammatory biomarkers. Twenty healthy men followed three 4-week diets in a randomised cross-over design: a Western diet, rich in saturated fat (22% SFA, 12% MUFA and 0.4% alpha-linolenic acid (ALA), all fractions are % of energy); a Mediterranean diet, rich in MUFA ( < 10 % SFA, 24 % MUFA and 0.4% ALA); a low-fat diet enriched in ALA ( < 10% SFA, 12% MUFA and 2% ALA). At the end of each dietary period all subjects underwent a postprandial study. Plasma concentrations of lipid parameters, soluble intercellular cell-adhesion molecule-1, soluble vascular cell-adhesion molecule-1 (sVCAM-1), nitrates and nitrites (NOx) and endothelial function studied by laser Doppler were examined at 0, 2, 4, 6 and 8 h. The endothelium-dependent vasodilatory response was greater 4 h after the ingestion of the MUFA-rich diet than after the SFA or ALA low-fat diets (P = 0.031). The 4 h postprandial plasma sVCAM-1 levels were lower after the MUFA meals than after the ALA low-fat diet (P = 0.043). The bioavailability of NOx was higher following the MUFA diet than after the SFA and ALA low-fat diets (P = 0.027). We found no differences in the other parameters measured. Chronic ingestion of a Mediterranean diet avoids the postprandial deterioration of endothelial function associated with Westernised diets in healthy individuals.

Journal ArticleDOI
TL;DR: Evidence is provided that Essure microinserts can be placed in a usual gynecologic consultation room in standard conditions without any type of anesthesia or sedation and are associated with great overall patient satisfaction.

Journal ArticleDOI
TL;DR: The Apuseni-Banat-Timok-Srednogorie magmatic-metallogenic belt (ABTS) as discussed by the authors is a large metallogenic province in the Balkan-South Carpathian system in southeastern Europe.
Abstract: The Apuseni–Banat–Timok–Srednogorie magmatic–metallogenic belt (ABTS belt), forms a substantial metallogenic province in the Balkan-South Carpathian system in southeastern Europe. The belt hosts porphyry, skarn, and epithermal deposits mined since pre-Roman times. Generally, the deposits, prospects, and occurrences within the belt are linked to magmatic centers of calc-alkaline affinity. Fifty-one rhenium-osmium (Re–Os) ages and Re concentration data for molybdenites define systematic geochronologic trends and constrain the geochemical-metallogenic evolution of the belt in space and time. From these data and additional existing geologic-geochemical data, a general tectonic history for the belt is proposed. Mineralization ages in Apuseni-Banat, Timok, and Panagyurishte (the central district of the larger E–W Srednogorie Zone) range from 72–83, 81–88, and 87–92 Ma, respectively, and clearly document increasing age from the northwestern districts to the southeastern districts. Further, Re–Os ages suggest rapidly migrating pulses of Late Cretaceous magmatic–hydrothermal activity with construction of deposits in ~1 m.y., districts in ~10 m.y., and the entire 1,500 km belt in ~20 m.y. Ages in both Timok and Panagyurishte show systematic younging, while deposit ages in Banat and Apuseni are less systematic reflecting a restricted evolution of the tectonic system. Systematic differences are also observed for molybdenite Re concentrations on the belt scale. Re concentrations generally range from hundreds to thousands of parts per million, typical of subduction-related Cu–Au–Mo–(PGE) porphyry systems associated with the generation of juvenile crust. The geochronologic and geochemical trends are compatible with proposed steepening of subducting oceanic slab and relaxation of upper continental plate compression. Resulting influx of sub-continental mantle lithosphere (SCML) and asthenosphere provide a fertile metal source and heat, while the subducting slab contributes connate and mineral dehydration fluids, which facilitate partial melting and metal leaching of SCML and asthenosphere. Cu–Au–Mo–(PGE) porphyry deposits may develop where melts are trapped at shallow crustal levels, often with associated volcanism and epithermal-style deposits (South Banat, Timok, and Panagyurishte). Mo–Fe–Pb–Zn skarn deposits may develop where felsic melts are trapped adjacent to Mesozoic limestones at moderate crustal levels (North Banat and Apuseni). Systematic spatial variations in deposit style, commodity enrichment, Re–Os ages, and Re concentrations support specific tectonic processes that led to ore formation. In a post-collisional setting, subduction of Vardar oceanic crust may have stalled, causing slab steepening and rollback. The slab rollback relaxes compression, facilitating and enhancing orogenic collapse of previously thickened Balkan-South Carpathian crust. The progression of coupled rollback-orogenic collapse is evidenced by the width of Late Cretaceous extensional basins and northward younging of Re–Os ages, from Panagyurishte (~60 km; 92–87 Ma) to Timok (~20 km; 88–81 Ma) to Apuseni-Banat (~5 km; 83–72 Ma). Generation of a well-endowed mineral belt, such as the ABTS, requires a temporally and spatially restricted window of magmatic–hydrothermal activity. This window is quickly opened as upper plate compression relaxes, thereby inducing melt generation and ingress of melt to higher crustal levels. The window is just as quickly closed as upper plate compression is reinstated. The transient tectonic state responsible for economic mineralization in the ABTS belt may be a paleo-analogue to transient intervals in the present subduction tectonics of SE Asia where much mineral wealth has been created in the last few million years.

Journal ArticleDOI
TL;DR: In this article, a review of lipid metabolism alterations associated with metabolic syndrome, paying special attention to changes in plasma lipids and cellular fatty acid oxidation, is presented, with particular reference to adipose and muscle tissues, and the mechanisms by which some adipokines, namely leptin and adiponectin, mediate the regulation of fatty acid oxidization in those tissues.
Abstract: The MS (metabolic syndrome) is a cluster of clinical and biochemical abnormalities characterized by central obesity, dyslipidaemia [hypertriglyceridaemia and decreased HDL-C (high-density lipoprotein cholesterol)], glucose intolerance and hypertension. Insulin resistance, hyperleptinaemia and low plasma levels of adiponectin are also widely related to features of the MS. This review focuses on lipid metabolism alterations associated with the MS, paying special attention to changes in plasma lipids and cellular fatty acid oxidation. Lipid metabolism alterations in liver and peripheral tissues are addressed, with particular reference to adipose and muscle tissues, and the mechanisms by which some adipokines, namely leptin and adiponectin, mediate the regulation of fatty acid oxidation in those tissues. Activation of the AMPK (AMP-dependent kinase) pathway, together with a subsequent increase in fatty acid oxidation, appear to constitute the main mechanism of action of these hormones in the regulation of lipid metabolism. Decreased activation of AMPK appears to have a role in the development of features of the MS. In addition, alteration of AMPK signalling in the hypothalamus, which may function as a sensor of nutrient availability, integrating multiple nutritional and hormonal signals, may have a key role in the appearance of the MS.

Journal ArticleDOI
TL;DR: A model for the viscous friction in foams and concentrated emulsions, subject to steady shear flow is presented, which predicts the macroscopic viscous stress of the sheared foam or emulsion.
Abstract: We present a model for the viscous friction in foams and concentrated emulsions, subject to steady shear flow. First, we calculate the energy dissipated due to viscous friction inside the films between two neighboring bubbles or drops, which slide along each other in the flow. Next, from this energy we calculate the macroscopic viscous stress of the sheared foam or emulsion. The model predictions agree well with experimental results obtained with foams and emulsions.

Journal ArticleDOI
TL;DR: The intriguing hypothesis that bacteria may have a role in essential oil biosynthesis opening the possibility to use them to manoeuvre the Vetiver oil molecular structure is supported.
Abstract: Vetiver is the only grass cultivated worldwide for the root essential oil, which is a mixture of sesquiterpene alcohols and hydrocarbons, used extensively in perfumery and cosmetics. Light and transmission electron microscopy demonstrated the presence of bacteria in the cortical parenchymatous essential oil-producing cells and in the lysigen lacunae in close association with the essential oil. This finding and the evidence that axenic Vetiver produces in vitro only trace amounts of oil with a strikingly different composition compared with the oils from in vivo Vetiver plants stimulated the hypothesis of an involvement of these bacteria in the oil metabolism. We used culture-based and culture-independent approaches to analyse the microbial community of the Vetiver root. Results demonstrate a broad phylogenetic spectrum of bacteria, including alpha-, beta- and gamma-Proteobacteria, high-G+C-content Gram-positive bacteria, and microbes belonging to the Fibrobacteres/Acidobacteria group. We isolated root-associated bacteria and showed that most of them are able to grow by using oil sesquiterpenes as a carbon source and to metabolize them releasing into the medium a large number of compounds typically found in commercial Vetiver oils. Several bacteria were also able to induce gene expression of a Vetiver sesquiterpene synthase. These results support the intriguing hypothesis that bacteria may have a role in essential oil biosynthesis opening the possibility to use them to manoeuvre the Vetiver oil molecular structure.

Journal ArticleDOI
TL;DR: Analysis of methylation changes of DNA repetitive elements during the progression of CML from chronic phase (CP) to blast crisis (BC) suggests that repetitive DNA hypomethylation are closely associated with CML progression.

Journal ArticleDOI
TL;DR: Considerable overlap is apparent between the two lesions, which suggests that they may represent opposite ends of the spectrum of the same process.

Journal ArticleDOI
TL;DR: In this paper, the authors presented balanced Hermitian structures on compact nilmanifolds in dimension six satisfying the heterotic supersymmetry equations with nonzero flux, non-flat instanton and constant dilaton which obey the three-form Bianchi identity with curvature term taken with respect to either the Levi-Civita, the (+)-connection or the Chern connection.
Abstract: We construct new explicit compact supersymmetric valid solutions with non-zero field strength, non-flat instanton and constant dilaton to the heterotic equations of motion in dimension six. We present balanced Hermitian structures on compact nilmanifolds in dimension six satisfying the heterotic supersymmetry equations with non-zero flux, non-flat instanton and constant dilaton which obey the three-form Bianchi identity with curvature term taken with respect to either the Levi-Civita, the (+)-connection or the Chern connection. Among them, all our solutions with respect to the (+)-connection on the compact nilmanifold $M_3$ satisfy the heterotic equations of motion.

Journal ArticleDOI
Salavat Abdullin1, Salavat Abdullin2, V. Abramov, B. S. Acharya3  +221 moreInstitutions (34)
TL;DR: In this article, the authors report on the test beam results and calibration methods using high energy electrons, pions and muons with the CMS forward calorimeter (HF), which is essential for a large number of physics channels with missing transverse energy.
Abstract: We report on the test beam results and calibration methods using high energy electrons, pions and muons with the CMS forward calorimeter (HF). The HF calorimeter covers a large pseudorapidity region (\(3\leq|\eta|\leq5\)), and is essential for a large number of physics channels with missing transverse energy. It is also expected to play a prominent role in the measurement of forward tagging jets in weak boson fusion channels in Higgs production. The HF calorimeter is based on steel absorber with embedded fused-silica-core optical fibers where Cherenkov radiation forms the basis of signal generation. Thus, the detector is essentially sensitive only to the electromagnetic shower core and is highly non-compensating (e/h≈5). This feature is also manifest in narrow and relatively short showers compared to similar calorimeters based on ionization. The choice of fused-silica optical fibers as active material is dictated by its exceptional radiation hardness. The electromagnetic energy resolution is dominated by photoelectron statistics and can be expressed in the customary form as \(\frac{a}{\sqrt{E}}\oplus{b}\). The stochastic term a is 198% and the constant term b is 9%. The hadronic energy resolution is largely determined by the fluctuations in the neutral pion production in showers, and when it is expressed as in the electromagnetic case, a = 280% and b = 11%.

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TL;DR: In this paper, a special class of scalar-tensor theories with charged black holes was considered, where the causal structure of the black holes has a single, non-degenerate horizon and their causal structure resembles that of the Schwarzschild black hole.
Abstract: Recent results show that when nonlinear electrodynamics is considered, the no-scalar-hair theorems in the scalar–tensor theories (STT) of gravity, which are valid for the cases of neutral black holes and charged black holes in the Maxwell electrodynamics, can be circumvented.1,2 What is even more, in the present work, we find new non-unique, numerical solutions describing charged black holes coupled to nonlinear electrodynamics in a special class of scalar–tensor theories. One of the phases has a trivial scalar field and coincides with the corresponding solution in General Relativity. The other phases that we find are characterized by the value of the scalar field charge. The causal structure and some aspects of the stability of the solutions have also been studied. For the scalar–tensor theories considered, the black holes have a single, non-degenerate horizon, i.e. their causal structure resembles that of the Schwarzschild black hole. The thermodynamic analysis of the stability of the solutions indicates that a phase transition may occur.

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TL;DR: A preferable octahedral environment around the transition metal centers is observed in polar solvents while the complexes retain their tetrahedral structure in non-polar media.

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TL;DR: In this article, the reduction of the string dynamics on AdS4 × 3 to the Neumann-Rosochatius integrable system was studied and the finite-size effects of the giant magnon and single spike solutions were analyzed.
Abstract: We use the reduction of the string dynamics on AdS4 × 3 to the Neumann-Rosochatius integrable system. All constraints can be expressed simply in terms of a few parameters. We analyze the giant magnon and single spike solutions on Rt × 3 with two angular momenta in detail and find the energy-charge relations. The finite-size effects of the giant magnon and single spike solutions are analyzed.

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TL;DR: Carbon was studied systematically by the adsorption of nitrogen and iodine and it was found that the process parameters such as activation temperature and activation time are crucial for preparing high-quality activated carbon.

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TL;DR: The experiments show that bubble breakup in foams occurs above a well defined critical dimensionless stress, tau[over]CR identical with(tauCRR/sigma) approximately 0.40, which is independent of surfactant used, solution viscosity, and bubble volume fraction, which evidences for facilitated drop subdivision in concentrated emulsions.
Abstract: This experimental study is focused on the process of bubble breakup in steadily sheared foams, at constant shear rate or constant shear stress. Two different types of surfactants were used and glycerol was added to the aqueous phase, to check how the bubble breakup depends on the surface modulus and on bulk viscosity of the foaming solutions. The experiments show that bubble breakup in foams occurs above a well defined critical dimensionless stress, ${\stackrel{\ifmmode \tilde{}\else \~{}\fi{}}{\ensuremath{\tau}}}_{\mathrm{CR}}\ensuremath{\equiv}({\ensuremath{\tau}}_{\mathrm{CR}}R∕\ensuremath{\sigma})\ensuremath{\approx}0.40$, which is independent of surfactant used, solution viscosity, and bubble volume fraction (varied between 92 and 98 %). Here ${\ensuremath{\tau}}_{\mathrm{CR}}$ is the dimensional shear stress, above which a bubble with radius $R$ and surface tension $\ensuremath{\sigma}$ would break in sheared foam. The value of the critical stress experimentally found by us ${\stackrel{\ifmmode \tilde{}\else \~{}\fi{}}{\ensuremath{\tau}}}_{\mathrm{CR}}\ensuremath{\approx}0.40$, is about two orders of magnitude lower than the critical stress for breakup of single bubbles in sheared Newtonian liquids, ${\stackrel{\ifmmode \tilde{}\else \~{}\fi{}}{\ensuremath{\tau}}}_{\mathrm{CR}}\ensuremath{\approx}25$. This large difference in the critical stress is explained by the strong interaction between neighboring bubbles in densely populated foams, which facilitates bubble subdivision into smaller bubbles. A strong effect of bubble polydispersity on the kinetics of bubble breakup (at similar mean bubble size) was observed and explained. Experiments were also performed with hexadecane-in-water emulsions of drop volume fraction 83% $\ensuremath{\leqslant}\ensuremath{\Phi}\ensuremath{\leqslant}95%$ to study drop breakup in concentrated emulsions. Qualitatively similar behavior was observed to that of foams, with the critical dimensionless stress for drop breakup being lower, ${\stackrel{\ifmmode \tilde{}\else \~{}\fi{}}{\ensuremath{\tau}}}_{\mathrm{CR}}\ensuremath{\approx}0.15$, and practically independent of the drop volume fraction and viscosity ratio (varied between 0.01 and 1). This critical stress is by several times lower than the critical stress for breakage of single drops in sheared Newtonian fluids at comparable viscosity ratio, which evidences for facilitated drop subdivision in concentrated emulsions. To explain the measured low values of the critical stress, a different type of capillary instability of the breaking bubbles and drops in concentrated foams and emulsions is proposed and discussed.