Institution
Sofia University
Education•Sofia, Bulgaria•
About: Sofia University is a education organization based out in Sofia, Bulgaria. It is known for research contribution in the topics: Large Hadron Collider & Standard Model. The organization has 8533 authors who have published 15730 publications receiving 306320 citations. The organization is also known as: University of Sofia & BFUS.
Topics: Large Hadron Collider, Standard Model, Population, Lepton, Laser
Papers published on a yearly basis
Papers
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Medical University of Warsaw1, University of Ulm2, Copenhagen University Hospital3, Hospital Sant Joan de Déu Barcelona4, University of Gothenburg5, Sahlgrenska University Hospital6, University of Colorado Denver7, University of Verona8, Cork University Hospital9, Sofia University10, Charles University in Prague11, Katholieke Universiteit Leuven12, Ege University13, National and Kapodistrian University of Athens14, Medical University of Vienna15, Semmelweis University16
TL;DR: Intensified insulin delivery using multiple daily injections (MDI) or continuous subcutaneous insulin infusion (CSII) is recommended in children with type 1 diabetes to achieve good metabolic control.
Abstract: Background
Intensified insulin delivery using multiple daily injections (MDI) or continuous subcutaneous insulin infusion (CSII) is recommended in children with type 1 diabetes (T1D) to achieve good metabolic control.
Objective
To examine the frequency of pump usage in T1D children treated in SWEET (Better control in Paediatric and Adolescent diabeteS: Working to crEate CEnTers of Reference) centers and to compare metabolic control between patients treated with CSII vs MDI.
Methods
This study included 16 570 T1D children participating in the SWEET prospective, multicenter, standardized diabetes patient registry. Datasets were aggregated over the most recent year of treatment for each patient. Data were collected until March 2016. To assess the organization of pump therapy a survey was carried out.
Results
Overall, 44.4% of T1D children were treated with CSII. The proportion of patients with pump usage varied between centers and decreased with increasing age compared with children treated with MDI. In a logistic regression analysis adjusting for age, gender and diabetes duration, the use of pump was associated with both: center size [odd ratio 1.51 (1.47-1.55), P < .0001) and the diabetes-related expenditure per capita [odd ratio 1.55 (1.49-1.61), P < .0001]. Linear regression analysis, adjusted for age, gender, and diabetes duration showed that both HbA1c and daily insulin dose (U/kg/d) remained decreased in children treated with CSII compared to MDI (P < .0001).
Conclusions
Insulin pump therapy is offered by most Sweet centers. The differences between centers affect the frequency of use of modern technology. Despite the heterogeneity of centers, T1D children achieve relatively good metabolic control, especially those treated with insulin pumps and those of younger age.
103 citations
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TL;DR: In this article, the authors investigated the hydrogen bonding between hydrogen fluoride and two series of molecules, nitrile and carbonyl compounds of the type R−CN and R−CHO, respectively, where R= −H, −OH, −SH, −OCH3, −NH2, −NO 2, −C⋮N, −F, −Cl, −CH3 and −CF3.
Abstract: Ab initio molecular orbital calculations at the HF/6-31+G(d,p) level were used to investigate the hydrogen bonding between hydrogen fluoride and two series of molecules, nitrile and carbonyl compounds of the type R−CN and R−CHO, respectively, where R= −H, −OH, −SH, −OCH3, −NH2, −NO2, −C⋮N, −F, −Cl, −CH3, and −CF3. Geometry optimization and vibrational frequency calculations at the optimized geometry were performed for isolated and hydrogen-bonded systems. The estimated energies of hydrogen-bond formation were corrected for zero-point vibrational energy and basis set superposition error (including the relaxation correction). Linear relations between the energy of hydrogen-bond formation (ΔE) and the H−F stretching frequency shift (ΔνHF) are obtained for the two series studied. Linear dependencies are also found between ΔE and the change of H−F bond length (ΔrHF). An excellent linear dependence is found between ΔER-CN and the ab initio calculated molecular electrostatic potential at the nitrile nitrogen (VN...
103 citations
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TL;DR: In this article, a search for a Higgs boson in the four-lepton decay channel H→ZZ, with each Z boson decaying to an electron or muon pair, is reported.
Abstract: A search for a Higgs boson in the four-lepton decay channel H→ZZ, with each Z boson decaying to an electron or muon pair, is reported. The search covers Higgs boson mass hypotheses in the range of 110 100 GeV (with 13 below 160 GeV), while 67.1±6.0 (9.5±1.3) events are expected from background. The four-lepton mass distribution is consistent with the expectation of standard model background production of ZZ pairs. Upper limits at 95% confidence level exclude the standard model Higgs boson in the ranges of 134–158 GeV, 180–305 GeV, and 340–465 GeV. Small excesses of events are observed around masses of 119, 126, and 320 GeV, making the observed limits weaker than expected in the absence of a signal.
103 citations
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TL;DR: In this article, the analysis of the Raman scattering cross section of the radial breathing modes of double-wall carbon nanotubes allowed the authors to determine the optical transitions of the inner tubes.
Abstract: The analysis of the Raman scattering cross section of the radial breathing modes of double-wall carbon nanotubes allowed us to determine the optical transitions of the inner tubes. The Raman lines are found to cluster into species with similar resonance behavior. The lowest components of the clusters correspond well to sodium sodecyl sulfate wrapped high pressure carbon monoxide grown tubes. Each cluster represents one particular inner tube inside different outer tubes and each member of the clusters represents one well-defined pair of inner and outer tubes. The number of components in one cluster increases with the decreasing inner tube diameter and can be as high as 14 spread over $30\phantom{\rule{0.3em}{0ex}}{\mathrm{cm}}^{\ensuremath{-}1}$. This suggests a lot of variation in the diameter difference of inner-outer tube pairs.
103 citations
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TL;DR: The concentration of glucose, insulin, IL-6 and IGF-1 in blood are useful markers for the selection of patients with liver steatosis or NASH in morbidly obese patients.
Abstract: Lipid accumulation and other histological liver markers characterize patients with non-alcoholic steatohepatitis (NASH). The identification of non-invasive prognostic factors of liver steatosis and NASH are relevant for the unravelling of the mechanisms of this disease, as well as for the clinical diagnoses of these patients. 36 patients with morbid obesity and 12 healthy subjects were consecutively enrolled in this cross-sectional study to determine the serological parameters associated with the degree of hepatic steatosis and NASH. Clinical, biochemical and histologic variables were examined in blood and liver biopsies by descriptive, univariate and multivariate regression analysis. The patients were distributed as non-NASH (14), probably-NASH (13) and NASH (9), according to the Non-alcoholic fatty liver disease Activity Score (NAS). The study identified remarkable differences in liver steatosis, and glucose, insulin, IL-6 and IGF-1 concentrations in blood among patients with morbid obesity. IL-6 was correlated with the degree of liver steatosis until the morbidly obese patients fulfil the criteria of NASH. The patients with NASH reduced IL-6 concentration in blood. IGF-1 decreased throughout the progression of NASH. TNF-α concentration was not related to liver steatosis or NASH in morbidly obese patients.The multivariate regression analysis identified glucose >110 mg/dL, IL-6 >4.81 pg/mL and IGF-1 4.5 and IGF-1 <110 ng/mL as independent predictors of hepatic steatosis and NASH, respectively. The concentration of glucose, insulin, IL-6 and IGF-1 in blood are useful markers for the selection of patients with liver steatosis or NASH.
102 citations
Authors
Showing all 8600 results
Name | H-index | Papers | Citations |
---|---|---|---|
Michael Tytgat | 134 | 1449 | 94133 |
Leander Litov | 133 | 1424 | 92713 |
Eric Conte | 132 | 1206 | 84593 |
Georgi Sultanov | 132 | 1493 | 93318 |
Plamen Iaydjiev | 131 | 1285 | 87958 |
Anton Dimitrov | 130 | 1236 | 86919 |
Jordan Damgov | 129 | 1195 | 85490 |
Borislav Pavlov | 129 | 1245 | 86458 |
Jean-Laurent Agram | 128 | 1221 | 84423 |
Cristina Botta | 128 | 1160 | 79070 |
Jean-Charles Fontaine | 128 | 1190 | 84011 |
Peicho Petkov | 128 | 1111 | 83495 |
Muhammad Ahmad | 128 | 1187 | 79758 |
Roumyana Hadjiiska | 126 | 1003 | 73091 |
Mircho Rodozov | 124 | 972 | 70519 |