Institution
Sofia University
Education•Sofia, Bulgaria•
About: Sofia University is a education organization based out in Sofia, Bulgaria. It is known for research contribution in the topics: Large Hadron Collider & Standard Model. The organization has 8533 authors who have published 15730 publications receiving 306320 citations. The organization is also known as: University of Sofia & BFUS.
Topics: Large Hadron Collider, Standard Model, Population, Lepton, Laser
Papers published on a yearly basis
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Claude Bernard University Lyon 11, Hungarian Natural History Museum2, University of Buenos Aires3, National Autonomous University of Mexico4, Sofia University5, University of Granada6, Moscow State University7, Atatürk University8, American Museum of Natural History9, University of Birjand10, University of Hull11, University College London12
TL;DR: The 5th meeting of the IUGS Lower Cretaceous Ammonite Working Group (the Kilian Group) held in Ankara, Turkey, 31st August 2013, discussed the Mediterranean ammonite zonation, and its calibration with different ammonite Zonal schemes of the Boreal, Austral and Central Atlantic realms as mentioned in this paper.
130 citations
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TL;DR: It can be speculated that in cancer patients the TIGIT/PVRIG pathways are upregulated and represent novel targets for checkpoint blockade immunotherapy.
Abstract: Natural killer (NK) cells are lymphocytes of the innate immune response characterized by their role in the destruction of tumor cells. Activation of NK cells depend on a fine balance between activating and inhibitory signals mediated by different receptors. In recent years, a family of paired receptors that interact with ligands of the Nectin/Nectin-like (Necl) family has attracted great interest. Two of these ligands, Necl-5 (usually termed CD155 or PVR) and Nectin-2 (CD112), frequently expressed on different types of tumor cells, are recognized by a group of receptors expressed on T and NK cells that exert opposite functions after interacting with their ligands. These receptors include DNAM-1 (CD226), TIGIT, TACTILE (CD96) and the recently described PVRIG. Whereas activation through DNAM-1 after recognition of CD155 or CD112 enhances NK cell-mediated cytotoxicity against a wide range of tumor cells, TIGIT recognition of these ligands exerts an inhibitory effect on NK cells by diminishing IFN-γ production, as well as NK cell-mediated cytotoxicity. PVRIG has also been identified as an inhibitory receptor that recognizes CD112 but not CD155. However, little is known about the role of TACTILE as modulator of immune responses in humans. TACTILE control of tumor growth and metastases has been reported in murine models, and it has been suggested that it negatively regulates the anti-tumor functions mediated by DNAM-1. In NK cells from patients with solid cancer and leukemia, it has been observed a decreased expression of DNAM-1 that may shift the balance in favor to the inhibitory receptors TIGIT or PVRIG, further contributing to the diminished NK cell-mediated cytotoxic capacity observed in these patients. Analysis of DNAM-1, TIGIT, TACTILE and PVRIG on human NK cells from solid cancer or leukemia patients will clarify the role of these receptors in cancer surveillance. Overall, it can be speculated that in cancer patients the TIGIT/PVRIG pathways are upregulated and represent novel targets for checkpoint blockade immunotherapy.
130 citations
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18 Dec 2013
TL;DR: In this article, the polarizations of the prompt J/ψJ /ψ and ψ(2S)ψ( 2S) mesons were measured in proton-proton collisions at View the MathML sources=7 TeV, using a dimuon data sample collected by the CMS experiment at the LHC, corresponding to an integrated luminosity of 4.9 fb−1.2.
Abstract: The polarizations of prompt J/ψJ/ψ and ψ(2S)ψ(2S) mesons are measured in proton–proton collisions at View the MathML sources=7 TeV, using a dimuon data sample collected by the CMS experiment at the LHC, corresponding to an integrated luminosity of 4.9 fb−1. The prompt J/ψJ/ψ and ψ(2S)ψ(2S) polarization parameters λϑλϑ, λφλφ, and λϑφλϑφ, as well as the frame-invariant quantity View the MathML sourceλ˜, are measured from the dimuon decay angular distributions in three different polarization frames. The J/ψJ/ψ results are obtained in the transverse momentum range 14
130 citations
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TL;DR: In this paper, the dispersion of the LS latices in the composite was studied by X-ray diffraction (XRD) and transmission electron microscopy (TEM), and informa- tion on the rubber/LS interaction was received from Fourier transform infrared spectroscopy (FTIR) and dynamic me- chanical thermal analysis (DMTA).
Abstract: Natural rubber (NR), polyurethane rubber (PUR), and NR/PUR-based nanocomposites were produced from the related latices by adding a pristine synthetic lay- ered silicate (LS; sodium fluorohectorite) in 10 parts per hundred parts rubber (phr). The dispersion of the LS latices in the composite was studied by X-ray diffraction (XRD) and transmission electron microscopy (TEM). Further informa- tion on the rubber/LS interaction was received from Fourier transform infrared spectroscopy (FTIR) and dynamic me- chanical thermal analysis (DMTA). Tensile and tear tests were used to characterize the performance of the rubber nanocomposites. It was found that LS is more compatible and thus better intercalated by PUR than by NR. Further, LS was preferably located in the PUR phase in the blends, which exhibited excellent mechanical properties despite the incompatibility between NR and PUR. Nano-reinforcement was best reflected in stiffness- and strength-related proper- ties of the rubber composites. © 2004 Wiley Periodicals, Inc. J Appl Polym Sci 92: 543-551, 2004
130 citations
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TL;DR: Water-in-oil (W/O) emulsions that are stabilized by polystyrene latex particles with sulfate surface groups are investigated, and the Schulze-Hardy rule for the critical concentration of coagulation is applicable to emulsification, which has been confirmed with suspensions containing Na(+), Mg(2+), and Al(3+) counterions.
Abstract: Here, we investigate water-in-oil (W/O) emulsions that are stabilized by polystyrene latex particles with sulfate surface groups. The particles, which play the role of emulsifier, are initially contained in the disperse (water) phase. The existence of such emulsions formally contradicts the empirical Bancroft rule. Theoretical considerations predict that the drop diameter has to be inversely proportional to the particle concentration, but should be independent of the volume fraction of water. In addition, there should be a second emulsification regime, in which the drop diameter is determined by the input mechanical energy during the homogenization. The existence of these two regimes has been experimentally confirmed, and the obtained data agree well with the theoretical model. Stable W/O emulsions have been produced with hexadecane and tetradecane, while, in the case of more viscous and polar oils (soybean and silicone oil), the particles enter into the oily phase, and Pickering emulsions cannot be obtained. The formation of stable emulsions demands the presence of a relatively high concentration of electrolyte that lowers the electrostatic barrier to particle adsorption at the oil -water interface. Because the attachment of particles at the drop surfaces represents a kind of coagulation, it turns out that the Schulze -Hardy rule for the critical concentration of coagulation is applicable also to emulsification, which has been confirmed with suspensions containing Na + ,M g 2+ , and Al 3+ counterions. The increase of the particle and electrolyte concentrations and the decrease of the volume fraction of water are other factors that facilitate emulsification in the investigated system. To quantify the combined action of these factors, an experimental stability -instability diagram has been obtained.
130 citations
Authors
Showing all 8600 results
Name | H-index | Papers | Citations |
---|---|---|---|
Michael Tytgat | 134 | 1449 | 94133 |
Leander Litov | 133 | 1424 | 92713 |
Eric Conte | 132 | 1206 | 84593 |
Georgi Sultanov | 132 | 1493 | 93318 |
Plamen Iaydjiev | 131 | 1285 | 87958 |
Anton Dimitrov | 130 | 1236 | 86919 |
Jordan Damgov | 129 | 1195 | 85490 |
Borislav Pavlov | 129 | 1245 | 86458 |
Jean-Laurent Agram | 128 | 1221 | 84423 |
Cristina Botta | 128 | 1160 | 79070 |
Jean-Charles Fontaine | 128 | 1190 | 84011 |
Peicho Petkov | 128 | 1111 | 83495 |
Muhammad Ahmad | 128 | 1187 | 79758 |
Roumyana Hadjiiska | 126 | 1003 | 73091 |
Mircho Rodozov | 124 | 972 | 70519 |