Institution
South London and Maudsley NHS Foundation Trust
Healthcare•London, United Kingdom•
About: South London and Maudsley NHS Foundation Trust is a healthcare organization based out in London, United Kingdom. It is known for research contribution in the topics: Mental health & Population. The organization has 1968 authors who have published 3783 publications receiving 98182 citations. The organization is also known as: SLaM.
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Wellcome Trust Sanger Institute1, University of Michigan2, University of Oxford3, University of Geneva4, University of Exeter5, Greifswald University Hospital6, National Research Council7, University of Bristol8, University of Colorado Boulder9, Fred Hutchinson Cancer Research Center10, University of Washington11, SUNY Downstate Medical Center12, Erasmus University Rotterdam13, University of Trieste14, VU University Amsterdam15, King's College London16, South London and Maudsley NHS Foundation Trust17, University of Edinburgh18, Harvard University19, National Institutes of Health20, Harokopio University21, Innsbruck Medical University22, Broad Institute23, University of Helsinki24, Lund University25, Norwegian University of Science and Technology26, University of Cambridge27, University of Minnesota28, Technische Universität München29, University of North Carolina at Chapel Hill30, University of Toronto31, McGill University32, Leiden University33, University of Pennsylvania34, University of Groningen35, Utrecht University36, Churchill Hospital37
TL;DR: A reference panel of 64,976 human haplotypes at 39,235,157 SNPs constructed using whole-genome sequence data from 20 studies of predominantly European ancestry leads to accurate genotype imputation at minor allele frequencies as low as 0.1% and a large increase in the number of SNPs tested in association studies.
Abstract: We describe a reference panel of 64,976 human haplotypes at 39,235,157 SNPs constructed using whole-genome sequence data from 20 studies of predominantly European ancestry. Using this resource leads to accurate genotype imputation at minor allele frequencies as low as 0.1% and a large increase in the number of SNPs tested in association studies, and it can help to discover and refine causal loci. We describe remote server resources that allow researchers to carry out imputation and phasing consistently and efficiently.
2,149 citations
TL;DR: The systematic review and meta-analysis revealed that during the acute illness, common symptoms among patients admitted to hospital for SARS or MERS included confusion and depression, and in one study traumatic memories.
1,701 citations
TL;DR: Mental health in the UK had deteriorated compared with pre-COVID-19 trends by late April, 2020, and policies emphasising the needs of women, young people and those with preschool aged children are likely to play an important part in preventing future mental illness.
1,636 citations
TL;DR: This large‐scale meta‐analysis confirms that SMI patients have significantly increased risk of CVD and CVD‐related mortality, and that elevated body mass index, antipsychotic use, andCVD screening and management require urgent clinical attention.
995 citations
University of Oxford1, Northumberland, Tyne and Wear NHS Foundation Trust2, Imperial College London3, University of Melbourne4, Cognition and Brain Sciences Unit5, King's College London6, Fulbourn Hospital7, University Hospitals Birmingham NHS Foundation Trust8, University of California, Los Angeles9, University of Cambridge10, South London and Maudsley NHS Foundation Trust11
TL;DR: The British Association for Psychopharmacology guidelines specify the scope and targets of treatment for bipolar disorder, and recommend strategies for the use of medicines in short-term treatment of episodes, relapse prevention and stopping treatment.
Abstract: The British Association for Psychopharmacology guidelines specify the scope and targets of treatment for bipolar disorder. The third version is based explicitly on the available evidence and presented, like previous Clinical Practice Guidelines, as recommendations to aid clinical decision making for practitioners: it may also serve as a source of information for patients and carers, and assist audit. The recommendations are presented together with a more detailed review of the corresponding evidence. A consensus meeting, involving experts in bipolar disorder and its treatment, reviewed key areas and considered the strength of evidence and clinical implications. The guidelines were drawn up after extensive feedback from these participants. The best evidence from randomized controlled trials and, where available, observational studies employing quasi-experimental designs was used to evaluate treatment options. The strength of recommendations has been described using the GRADE approach. The guidelines cover the diagnosis of bipolar disorder, clinical management, and strategies for the use of medicines in short-term treatment of episodes, relapse prevention and stopping treatment. The use of medication is integrated with a coherent approach to psychoeducation and behaviour change.
989 citations
Authors
Showing all 1997 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Terrie E. Moffitt | 182 | 594 | 150609 |
| Robin M. Murray | 171 | 1539 | 116362 |
| Steven Williams | 144 | 1375 | 86712 |
| Philip McGuire | 133 | 881 | 60813 |
| David Taylor | 131 | 2469 | 93220 |
| Gareth J. Barker | 122 | 800 | 54466 |
| Simon Wessely | 122 | 868 | 62843 |
| Jim van Os | 118 | 852 | 87111 |
| Peter McGuffin | 117 | 624 | 62968 |
| Clive Ballard | 117 | 736 | 61663 |
| Anthony S. David | 116 | 817 | 53284 |
| Thomas J. Spencer | 116 | 531 | 52743 |
| Janet Treasure | 114 | 831 | 44104 |
| Dag Aarsland | 109 | 616 | 52740 |
| Andrew Pickles | 109 | 436 | 55981 |