Southeast University

About: Southeast University is a education organization based out in Nanjing, China. It is known for research contribution in the topics: Computer science & MIMO. The organization has 66363 authors who have published 79434 publications receiving 1170576 citations. The organization is also known as: SEU.

Detecting topological invariants in nonunitary discrete-time quantum walks

Abstract: We report the experimental detection of bulk topological invariants in nonunitary discrete-time quantum walks with single photons The nonunitarity of the quantum dynamics is enforced by periodically performing partial measurements on the polarization of the walker photon, which effectively introduces loss to the dynamics The topological invariant of the nonunitary quantum walk is manifested in the quantized average displacement of the walker, which is probed by monitoring the photon loss We confirm the topological properties of the system by observing localized edge states at the boundary of regions with different topological invariants We further demonstrate the robustness of both the topological properties and the measurement scheme of the topological invariants against disorder

Molecular basis for H3K36me3 recognition by the Tudor domain of PHF1

Abstract: The PHD finger protein 1 (PHF1) is essential in epigenetic regulation and genome maintenance. Here we show that the Tudor domain of human PHF1 binds to histone H3 trimethylated at Lys36 (H3K36me3). We report a 1.9-A resolution crystal structure of the Tudor domain in complex with H3K36me3 and describe the molecular mechanism of H3K36me3 recognition using NMR. Binding of PHF1 to H3K36me3 inhibits the ability of the Polycomb PRC2 complex to methylate Lys27 of histone H3 in vitro and in vivo. Laser microirradiation data show that PHF1 is transiently recruited to DNA double-strand breaks, and PHF1 mutants impaired in the H3K36me3 interaction exhibit reduced retention at double-strand break sites. Together, our findings suggest that PHF1 can mediate deposition of the repressive H3K27me3 mark and acts as a cofactor in early DNA-damage response.

Global Synchronization Control of General Delayed Discrete-Time Networks With Stochastic Coupling and Disturbances

Abstract: In this paper, the synchronization control problem is considered for two coupled discrete-time complex networks with time delays. The network under investigation is quite general to reflect the reality, where the state delays are allowed to be time varying with given lower and upper bounds, and the stochastic disturbances are assumed to be Brownian motions that affect not only the network coupling but also the overall networks. By utilizing the Lyapunov functional method combined with linear matrix inequality (LMI) techniques, we obtain several sufficient delay-dependent conditions that ensure the coupled networks to be globally exponentially synchronized in the mean square. A control law is designed to synchronize the addressed coupled complex networks in terms of certain LMIs that can be readily solved using the Matlab LMI toolbox. Two numerical examples are presented to show the validity of our theoretical analysis results.