Southeast University

About: Southeast University is a education organization based out in Nanjing, China. It is known for research contribution in the topics: MIMO & Control theory. The organization has 66363 authors who have published 79434 publications receiving 1170576 citations. The organization is also known as: SEU.

An Amateur Drone Surveillance System Based on the Cognitive Internet of Things

Abstract: Drones, also known as mini-unmanned aerial vehicles, have attracted increasing attention due to their boundless applications in communications, photography, agriculture, surveillance, and numerous public services. However, the deployment of amateur drones poses various safety, security, and privacy threats. To cope with these challenges, amateur drone surveillance has become a very important but largely unexplored topic. In this article, we first present a brief survey to show the stateof- the-art studies on amateur drone surveillance. Then we propose a vision, named Dragnet, tailoring the recently emerging Cognitive Internet of Things framework for amateur drone surveillance. Next, we discuss the key enabling techniques for Dragnet in detail, accompanied by the technical challenges and open issues. Furthermore, we provide an exemplary case study on the detection and classification of authorized and unauthorized amateur drones, where, for example, an important event is being held and only authorized drones are allowed to fly over.

Long noncoding RNA PVT1 indicates a poor prognosis of gastric cancer and promotes cell proliferation through epigenetically regulating p15 and p16

Abstract: Mounting evidence indicates that long noncoding RNAs (lncRNAs) could play a pivotal role in cancer biology. However, the overall biological role and clinical significance of PVT1 in gastric carcinogenesis remains largely unknown. Expression of PVT1 was analyzed in 80 GC tissues and cell lines by qRT-PCR. The effect of PVT1 on proliferation was evaluated by MTT and colony formation assays, and cell apoptosis was evaluated by Flow-cytometric analysis. GC cells transfected with shPVT1 were injected into nude mice to study the effect of PVT1 on tumorigenesis in vivo. RIP was performed to confirm the interaction between PVT1 and EZH2. ChIP was used to study the promoter region of related genes. The higher expression of PVT1 was significantly correlated with deeper invasion depth and advanced TNM stage. Multivariate analyses revealed that PVT1 expression served as an independent predictor for overall survival (p = 0.031). Further experiments demonstrated that PVT1 knockdown significantly inhibited the proliferation both in vitro and in vivo. Importantly, we also showed that PVT1 played a key role in G1 arrest. Moreover, we further confirmed that PVT1 was associated with enhancer of zeste homolog 2 (EZH2) and that this association was required for the repression of p15 and p16. To our knowledge, this is the first report showed that the role and the mechanism of PVT1 in the progression of gastric cancer. Together, these results suggest that lncRNA PVT1 may serve as a candidate prognostic biomarker and target for new therapies in human gastric cancer.