Institution
Southwest University
Education•Chongqing, China•
About: Southwest University is a education organization based out in Chongqing, China. It is known for research contribution in the topics: Population & Bombyx mori. The organization has 29772 authors who have published 27755 publications receiving 409441 citations. The organization is also known as: Southwest University in Chongqing & SWU.
Topics: Population, Bombyx mori, Gene, Electrochemiluminescence, Biosensor
Papers published on a yearly basis
Papers
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TL;DR: The results based on the satellite record show that phenology change rate in the northern hemisphere slowed down during the warming hiatus, and this has significant implications for understanding the responses of phenology to climate change and the climate-carbon feedbacks.
Abstract: Phenology plays a fundamental role in regulating photosynthesis, evapotranspiration, and surface energy fluxes and is sensitive to climate change. The global mean surface air temperature data indicate a global warming hiatus between 1998 and 2012, while its impacts on global phenology remains unclear. Here we use long-term satellite and FLUXNET records to examine phenology trends in the northern hemisphere before and during the warming hiatus. Our results based on the satellite record show that the phenology change rate slowed down during the warming hiatus. The analysis of the long-term FLUXNET measurements, mainly within the warming hiatus, shows that there were no widespread advancing (or delaying) trends in spring (or autumn) phenology. The lack of widespread phenology trends partly led to the lack of widespread trends in spring and autumn carbon fluxes. Our findings have significant implications for understanding the responses of phenology to climate change and the climate-carbon feedbacks.
128 citations
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TL;DR: The development and biomedical application of nucleic acid aptamers are discussed, with emphasis on cancer cell aptamer isolation, targeted cancer therapy, oncology biomarker identification and drug discovery.
128 citations
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01 Jan 2019TL;DR: The results show that the credibility of information in the D-AHP method slightly impacts the ranking of alternatives, but the priority weights of alternatives are influenced in a relatively obvious extent.
Abstract: Multi-criteria decision making (MCDM) has attracted wide interest due to its extensive applications in practice. In our previous study, a method called D-AHP (AHP method extended by D numbers preference relation) was proposed to study the MCDM problems based on a D numbers extended fuzzy preference relation, and a solution for the D-AHP method has been given to obtain the weights and ranking of alternatives from the decision data, in which the results obtained by using the D-AHP method are influenced by the credibility of information. However, in previous study the impact of information’s credibility on the results is not sufficiently investigated, which becomes an unsolved issue in the D-AHP. In this paper, we focus on the credibility of information within the D-AHP method and study its impact on the results of a MCDM problem. Information with different credibilities including high, medium and low, respectively, is taken into consideration. The results show that the credibility of information in the D-AHP method slightly impacts the ranking of alternatives, but the priority weights of alternatives are influenced in a relatively obvious extent.
128 citations
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TL;DR: Bacterial thiamin biosynthetic, salvage, and transport pathways are described and essential thiamIn synthetic enzymes such as Dxs and ThiE are proposed as promising drug targets.
Abstract: Drug resistance of pathogens has necessitated the identification of novel targets for antibiotics. Thiamin (vitamin B1) is an essential cofactor for all organisms in its active form thiamin diphosphate (ThDP). Therefore, its metabolic pathways might be one largely untapped source of antibiotics targets. This review describes bacterial thiamin biosynthetic, salvage, and transport pathways. Essential thiamin synthetic enzymes such as Dxs and ThiE are proposed as promising drug targets. The regulation mechanism of thiamin biosynthesis by ThDP riboswitch is also discussed. As drug targets of existing antimicrobial compound pyrithiamin, the ThDP riboswitch might serves as alternative targets for more antibiotics.
128 citations
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ETH Zurich1, East Carolina University2, Illinois State University3, Swiss Institute of Bioinformatics4, Royal Holloway, University of London5, Ghent University6, Maynooth University7, Trinity College, Dublin8, Queen Mary University of London9, University of Agricultural Sciences, Dharwad10, Martin Luther University of Halle-Wittenberg11, Agricultural Research Service12, Southwest University13, University of Geneva14
TL;DR: The immune repertoire of two ecologically and commercially important bumblebee species that diverged approximately 18 million years ago are described, finding that the immune systems of these bumblebees, two species of honeybee, and a solitary leafcutting bee, are strikingly similar.
Abstract: Sociality has many rewards, but can also be dangerous, as high population density and low genetic diversity, common in social insects, is ideal for parasite transmission. Despite this risk, honeybees and other sequenced social insects have far fewer canonical immune genes relative to solitary insects. Social protection from infection, including behavioral responses, may explain this depauperate immune repertoire. Here, based on full genome sequences, we describe the immune repertoire of two ecologically and commercially important bumblebee species that diverged approximately 18 million years ago, the North American Bombus impatiens and European Bombus terrestris. We find that the immune systems of these bumblebees, two species of honeybee, and a solitary leafcutting bee, are strikingly similar. Transcriptional assays confirm the expression of many of these genes in an immunological context and more strongly in young queens than males, affirming Bateman’s principle of greater investment in female immunity. We find evidence of positive selection in genes encoding antiviral responses, components of the Toll and JAK/STAT pathways, and serine protease inhibitors in both social and solitary bees. Finally, we detect many genes across pathways that differ in selection between bumblebees and honeybees, or between the social and solitary clades. The similarity in immune complement across a gradient of sociality suggests that a reduced immune repertoire predates the evolution of sociality in bees. The differences in selection on immune genes likely reflect divergent pressures exerted by parasites across social contexts.
128 citations
Authors
Showing all 29978 results
Name | H-index | Papers | Citations |
---|---|---|---|
Frank B. Hu | 250 | 1675 | 253464 |
Hongjie Dai | 197 | 570 | 182579 |
Jing Wang | 184 | 4046 | 202769 |
Chao Zhang | 127 | 3119 | 84711 |
Jianjun Liu | 112 | 1040 | 71032 |
Miao Liu | 111 | 993 | 59811 |
Jun Yang | 107 | 2090 | 55257 |
Eric Westhof | 98 | 472 | 34825 |
En-Tang Kang | 97 | 763 | 38498 |
Chang Ming Li | 97 | 896 | 42888 |
Wei Zhou | 93 | 1640 | 39772 |
Li Zhang | 92 | 918 | 35648 |
Heinz Rennenberg | 87 | 527 | 26359 |
Tao Chen | 86 | 820 | 27714 |
Xun Wang | 84 | 606 | 32187 |