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Institution

Southwest University

EducationChongqing, China
About: Southwest University is a education organization based out in Chongqing, China. It is known for research contribution in the topics: Gene & Population. The organization has 29772 authors who have published 27755 publications receiving 409441 citations. The organization is also known as: Southwest University in Chongqing & SWU.
Topics: Gene, Population, Catalysis, Bombyx mori, Adsorption


Papers
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Journal ArticleDOI
TL;DR: A series of novel amine-derived bis-azole compounds were designed by the systematical structural modification of Fluconazole and synthesized by a convenient and efficient method, and the antimicrobial activities were evaluated in vitro against six representative bacterial strains and two fungal strains.

104 citations

Journal ArticleDOI
TL;DR: It is reported that KDM4C transcriptionally activates amino acid biosynthesis and transport, leading to a significant increase in intracellular amino acid levels, suggesting a molecular mechanism linking KDM3K9 demethylation and ATF4-mediated transactivation in reprogramming amino acid metabolism for cancer cell proliferation.

104 citations

Journal ArticleDOI
Fuyuan Xiao1
TL;DR: From the experimental results, it is demonstrated that the proposed method outperforms the related methods, because the uncertainty resulting from human’s subjective cognition can be reduced; meanwhile, the decision-making level can also be improved with better performance.
Abstract: The existing approaches for fuzzy soft sets decision-making are mainly based on different types of level soft sets. How to deal with such kinds of fuzzy soft sets decision-making problems via decreasing the uncertainty resulting from human’s subjective cognition is still an open issue. To address this issue, a hybrid method for utilizing fuzzy soft sets in decision-making by integrating a fuzzy preference relations analysis based on the belief entropy with the Dempster–Shafer evidence theory is proposed. The proposed method is composed of four procedures. First, we measure the uncertainties of parameters by leveraging the belief entropy. Second, with the fuzzy preference relations analysis, the uncertainties of parameters are modulated by making use of the relative reliability preference of parameters. Third, an appropriate basic probability assignment in terms of each parameter is generated on the modulated uncertainty degrees of parameters basis. Finally, we adopt Dempster’s combination rule to fuse the independent parameters into an integrated one; thus, the best one can be obtained based on the ranking candidate alternatives. In order to validate the feasibility and effectiveness of the proposed method, a numerical example and a medical diagnosis application are implemented. From the experimental results, it is demonstrated that the proposed method outperforms the related methods, because the uncertainty resulting from human’s subjective cognition can be reduced; meanwhile, the decision-making level can also be improved with better performance.

104 citations

Journal ArticleDOI
Ying Huang1, Jin Xu1, Liu Junjie1, Wang Xiangyang1, Bin Chen1 
17 Oct 2017-Sensors
TL;DR: Research trends in disease-related detection with electrochemical biosensors are reviewed, and focus has been placed on the immobilization mechanism of electrochemicals, and the techniques and materials used for the fabrication of biosensor are introduced.
Abstract: Rapid diagnosis of diseases at their initial stage is critical for effective clinical outcomes and promotes general public health. Classical in vitro diagnostics require centralized laboratories, tedious work and large, expensive devices. In recent years, numerous electrochemical biosensors have been developed and proposed for detection of various diseases based on specific biomarkers taking advantage of their features, including sensitivity, selectivity, low cost and rapid response. This article reviews research trends in disease-related detection with electrochemical biosensors. Focus has been placed on the immobilization mechanism of electrochemical biosensors, and the techniques and materials used for the fabrication of biosensors are introduced in details. Various biomolecules used for different diseases have been listed. Besides, the advances and challenges of using electrochemical biosensors for disease-related applications are discussed.

104 citations

Journal ArticleDOI
TL;DR: Based on a unique dataset consisting of the GPS trajectories of 10 million travels accomplished by 150,000 cars in Italy, it is found how to build an extremely accurate model that estimates the real traffic values as measured by road sensors.
Abstract: Are the patterns of car travel different from those of general human mobility? Based on a unique dataset consisting of the GPS trajectories of 10 million travels accomplished by 150,000 cars in Italy, we investigate how known mobility models apply to car travels, and illustrate novel analytical findings. We also assess to what extent the sample in our dataset is representative of the overall car mobility, and discover how to build an extremely accurate model that, given our GPS data, estimates the real traffic values as measured by road sensors.

104 citations


Authors

Showing all 29978 results

NameH-indexPapersCitations
Frank B. Hu2501675253464
Hongjie Dai197570182579
Jing Wang1844046202769
Chao Zhang127311984711
Jianjun Liu112104071032
Miao Liu11199359811
Jun Yang107209055257
Eric Westhof9847234825
En-Tang Kang9776338498
Chang Ming Li9789642888
Wei Zhou93164039772
Li Zhang9291835648
Heinz Rennenberg8752726359
Tao Chen8682027714
Xun Wang8460632187
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202395
2022461
20213,538
20203,257
20192,923
20182,479