Southwest University

About: Southwest University is a education organization based out in Chongqing, China. It is known for research contribution in the topics: Gene & Population. The organization has 29772 authors who have published 27755 publications receiving 409441 citations. The organization is also known as: Southwest University in Chongqing & SWU.

Suppression of time delay signatures of chaotic output in a semiconductor laser with double optical feedback

Abstract: We experimentally and numerically demonstrate the time delay (TD) signature suppression of chaotic output in a double optical feedback semiconductor laser (DOF-SL) system. Two types of TD signature suppression are demonstrated by adjusting the lengths and the feedback power ratios of the two external cavities. One can significantly eliminate all TD signatures of the DOF-SL system and the corresponding power spectrum distribution becomes quite smooth and flat, the other suppresses one of two TD signatures and remains another one.

Rolling Circular Amplification (RCA)-Assisted CRISPR/Cas9 Cleavage (RACE) for Highly Specific Detection of Multiple Extracellular Vesicle MicroRNAs

Abstract: Multiplexed detection of extracellular vesicle (EV)-derived microRNAs (miRNAs) plays a critical role in facilitating disease diagnosis and prognosis evaluation. Herein, we developed a highly specific nucleic acid detection platform for simultaneous quantification of several EV-derived miRNAs in constant temperature by integrating the advantages of a clustered regularly interspaced short palindromic repeats/CRISPR associated nucleases (CRISPR/Cas) system and rolling circular amplification (RCA) techniques. Particularly, the proposed approach demonstrated single-base resolution attributed to the dual-specific recognition from both padlock probe-mediated ligation and protospacer adjacent motif (PAM)-triggered cleavage. The high consistency between the proposed approach RCA-assisted CRISPR/Cas9 cleavage (RACE) and reverse transcription quantitative polymerase chain reaction (RT-qPCR) in detecting EV-derived miRNAs' abundance from both cultured cancer cells and clinical lung cancer patients validated its robustness, revealing its potentials in the screening, diagnosis, and prognosis of various diseases. In summary, RACE is a powerful tool for multiplexed, specific detection of nucleic acids in point-of-care diagnostics and field-deployable analysis.

Exponential Stability of Complex-Valued Memristive Recurrent Neural Networks

Abstract: In this brief, we establish a novel complex-valued memristive recurrent neural network (CVMRNN) to study its stability. As a generalization of real-valued memristive neural networks, CVMRNN can be separated into real and imaginary parts. By means of $M$ -matrix and Lyapunov function, the existence, uniqueness, and exponential stability of the equilibrium point for CVMRNNs are investigated, and sufficient conditions are presented. Finally, the effectiveness of obtained results is illustrated by two numerical examples.