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Institution

Spanish National Research Council

GovernmentMadrid, Spain
About: Spanish National Research Council is a government organization based out in Madrid, Spain. It is known for research contribution in the topics: Population & Galaxy. The organization has 79563 authors who have published 220470 publications receiving 7698991 citations. The organization is also known as: CSIC & Consejo Superior de Investigaciones Científicas.
Topics: Population, Galaxy, Catalysis, Stars, Star formation


Papers
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Journal ArticleDOI
25 May 2000-Nature
TL;DR: Single crystals of silicon inverse opal with a complete three-dimensional photonic bandgap centred on 1.46 µm are described, produced by growing silicon inside the voids of an opal template of close-packed silica spheres that are connected by small ‘necks’ formed during sintering, followed by removal of the silica template.
Abstract: Photonic technology, using light instead of electrons as the information carrier, is increasingly replacing electronics in communication and information management systems. Microscopic light manipulation, for this purpose, is achievable through photonic bandgap materials1,2, a special class of photonic crystals in which three-dimensional, periodic dielectric constant variations controllably prohibit electromagnetic propagation throughout a specified frequency band. This can result in the localization of photons3,4,5,6, thus providing a mechanism for controlling and inhibiting spontaneous light emission that can be exploited for photonic device fabrication. In fact, carefully engineered line defects could act as waveguides connecting photonic devices in all-optical microchips7, and infiltration of the photonic material with suitable liquid crystals might produce photonic bandgap structures (and hence light-flow patterns) fully tunable by an externally applied voltage8,9,10. However, the realization of this technology requires a strategy for the efficient synthesis of high-quality, large-scale photonic crystals with photonic bandgaps at micrometre and sub-micrometre wavelengths, and with rationally designed line and point defects for optical circuitry. Here we describe single crystals of silicon inverse opal with a complete three-dimensional photonic bandgap centred on 1.46 µm, produced by growing silicon inside the voids of an opal template of close-packed silica spheres that are connected by small ‘necks’ formed during sintering, followed by removal of the silica template. The synthesis method is simple and inexpensive, yielding photonic crystals of pure silicon that are easily integrated with existing silicon-based microelectronics.

1,520 citations

Journal ArticleDOI
18 Jul 2008-Science
TL;DR: The large majority of antibiotics currently used for treating infections and the antibiotic resistance genes acquired by human pathogens each have an environmental origin and the function of these elements in their environmental reservoirs may be very distinct from the “weapon-shield” role they play in clinical settings.
Abstract: The large majority of antibiotics currently used for treating infections and the antibiotic resistance genes acquired by human pathogens each have an environmental origin. Recent work indicates that the function of these elements in their environmental reservoirs may be very distinct from the "weapon-shield" role they play in clinical settings. Changes in natural ecosystems, including the release of large amounts of antimicrobials, might alter the population dynamics of microorganisms, including selection of resistance, with consequences for human health that are difficult to predict.

1,519 citations

Journal ArticleDOI
12 Jun 2014-PLOS ONE
TL;DR: The additional genes identified in this study, have an array of functions previously implicated in Alzheimer's disease, including aspects of energy metabolism, protein degradation and the immune system and add further weight to these pathways as potential therapeutic targets in Alzheimers disease.
Abstract: Background: Alzheimer's disease is a common debilitating dementia with known heritability, for which 20 late onset susceptibility loci have been identified, but more remain to be discovered. This s ...

1,518 citations

Journal ArticleDOI
TL;DR: Analysis of the resulting networks in different tasks shows that the distribution of functional connections, and the probability of finding a link versus distance are both scale-free and the characteristic path length is small and comparable with those of equivalent random networks.
Abstract: Functional magnetic resonance imaging is used to extract functional networks connecting correlated human brain sites. Analysis of the resulting networks in different tasks shows that (a) the distribution of functional connections, and the probability of finding a link versus distance are both scale-free, (b) the characteristic path length is small and comparable with those of equivalent random networks, and (c) the clustering coefficient is orders of magnitude larger than those of equivalent random networks. All these properties, typical of scale-free small-world networks, reflect important functional information about brain states.

1,508 citations

Journal ArticleDOI
23 Dec 2010-Nature
TL;DR: A tooth found in Denisova Cave carries a mitochondrial genome highly similar to that of the finger bone, further indicating that Denisovans have an evolutionary history distinct from Neanderthals and modern humans.
Abstract: Using DNA extracted from a finger bone found in Denisova Cave in southern Siberia, we have sequenced the genome of an archaic hominin to about 1.9-fold coverage. This individual is from a group that shares a common origin with Neanderthals. This population was not involved in the putative gene flow from Neanderthals into Eurasians; however, the data suggest that it contributed 4–6% of its genetic material to the genomes of present-day Melanesians. We designate this hominin population ‘Denisovans’ and suggest that it may have been widespread in Asia during the Late Pleistocene epoch. A tooth found in Denisova Cave carries a mitochondrial genome highly similar to that of the finger bone. This tooth shares no derived morphological features with Neanderthals or modern humans, further indicating that Denisovans have an evolutionary history distinct from Neanderthals and modern humans.

1,506 citations


Authors

Showing all 79686 results

NameH-indexPapersCitations
Guido Kroemer2361404246571
George Efstathiou187637156228
Peidong Yang183562144351
H. S. Chen1792401178529
David R. Williams1782034138789
Andrea Bocci1722402176461
Adrian L. Harris1701084120365
Gang Chen1673372149819
Gregory J. Hannon165421140456
Alvaro Pascual-Leone16596998251
Jorge E. Cortes1632784124154
Dongyuan Zhao160872106451
John B. Goodenough1511064113741
David D'Enterria1501592116210
A. Gomes1501862113951
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20241
202371
2022463
202111,933
202012,584
201911,596