Institution
Spanish National Research Council
Government•Madrid, Spain•
About: Spanish National Research Council is a government organization based out in Madrid, Spain. It is known for research contribution in the topics: Population & Galaxy. The organization has 79563 authors who have published 220470 publications receiving 7698991 citations. The organization is also known as: CSIC & Consejo Superior de Investigaciones Científicas.
Topics: Population, Galaxy, Catalysis, Stars, Star formation
Papers published on a yearly basis
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TL;DR: In this article, the authors analyzed the Raman spectra of 29 different carbon materials, including all types of carbonaceous solids of practical interest, and found that the width of the D band correlates well with the degree of disorder over the entire order-disorder interval.
1,044 citations
TL;DR: The results show promising perspectives for the exploitation of non-traditional tropical fruit species with considerable levels of nutrients and antioxidant capacity, as well as the considerable antioxidant capacity found for acerola – Malpighia emarginata and camu-camu – Myrciaria dubia.
1,044 citations
TL;DR: In this paper, the authors propose a new framework to describe the structure and functioning of ecological networks and to assess the probable consequences of biodiversity change, by incorporating body size into theoretical models that explore food web stability and the patterning of energy fluxes.
Abstract: Body size determines a host of species traits that can affect the structure and dynamics of food webs, and other ecological networks, across multiple scales of organization. Measuring body size provides a relatively simple means of encapsulating and condensing a large amount of the biological information embedded within an ecological network. Recently, important advances have been made by incorporating body size into theoretical models that explore food web stability, the patterning of energy fluxes, and responses to perturbations. Because metabolic constraints underpin body-size scaling relationships, metabolic theory offers a potentially useful new framework within which to develop novel models to describe the structure and functioning of ecological networks and to assess the probable consequences of biodiversity change.
1,041 citations
TL;DR: This is the first report of spontaneous transformation of human adult stem cells, supporting the hypothesis of cancer stem cell origin, and indicates the importance of biosafety studies of mesenchymal stem cell biology to efficiently exploit their full clinical therapeutic potential.
Abstract: Human adult stem cells are being evaluated widely for various therapeutic approaches. Several recent clinical trials have reported their safety, showing them to be highly resistant to transformation. The clear similarities between stem cell and cancer stem cell genetic programs are nonetheless the basis of a recent proposal that some cancer stem cells could derive from human adult stem cells. Here we show that although they can be managed safely during the standard ex vivo expansion period (6-8 weeks), human mesenchymal stem cells can undergo spontaneous transformation following long-term in vitro culture (4-5 months). This is the first report of spontaneous transformation of human adult stem cells, supporting the hypothesis of cancer stem cell origin. Our findings indicate the importance of biosafety studies of mesenchymal stem cell biology to efficiently exploit their full clinical therapeutic potential.
1,039 citations
TL;DR: In the last 30 years, research efforts by the scientific community intensified significantly, stemming from the pioneering work of Takahashi and co-workers, with the initial development of mixed ionic-electronic conducting (MIEC) oxides.
1,037 citations
Authors
Showing all 79686 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Guido Kroemer | 236 | 1404 | 246571 |
| George Efstathiou | 187 | 637 | 156228 |
| Peidong Yang | 183 | 562 | 144351 |
| H. S. Chen | 179 | 2401 | 178529 |
| David R. Williams | 178 | 2034 | 138789 |
| Andrea Bocci | 172 | 2402 | 176461 |
| Adrian L. Harris | 170 | 1084 | 120365 |
| Gang Chen | 167 | 3372 | 149819 |
| Gregory J. Hannon | 165 | 421 | 140456 |
| Alvaro Pascual-Leone | 165 | 969 | 98251 |
| Jorge E. Cortes | 163 | 2784 | 124154 |
| Dongyuan Zhao | 160 | 872 | 106451 |
| John B. Goodenough | 151 | 1064 | 113741 |
| David D'Enterria | 150 | 1592 | 116210 |
| A. Gomes | 150 | 1862 | 113951 |