Spanish National Research Council

About: Spanish National Research Council is a government organization based out in Madrid, Spain. It is known for research contribution in the topics: Population & Galaxy. The organization has 79563 authors who have published 220470 publications receiving 7698991 citations. The organization is also known as: CSIC & Consejo Superior de Investigaciones Científicas.

Viral Quasispecies Evolution

Abstract: Summary: Evolution of RNA viruses occurs through disequilibria of collections of closely related mutant spectra or mutant clouds termed viral quasispecies. Here we review the origin of the quasispecies concept and some biological implications of quasispecies dynamics. Two main aspects are addressed: (i) mutant clouds as reservoirs of phenotypic variants for virus adaptability and (ii) the internal interactions that are established within mutant spectra that render a virus ensemble the unit of selection. The understanding of viruses as quasispecies has led to new antiviral designs, such as lethal mutagenesis, whose aim is to drive viruses toward low fitness values with limited chances of fitness recovery. The impact of quasispecies for three salient human pathogens, human immunodeficiency virus and the hepatitis B and C viruses, is reviewed, with emphasis on antiviral treatment strategies. Finally, extensions of quasispecies to nonviral systems are briefly mentioned to emphasize the broad applicability of quasispecies theory.

Tolerance of pea (Pisum sativum L.) to long‐term salt stress is associated with induction of antioxidant defences

Abstract: Using two cultivars of Pisum sativum L. with different sensitivity to NaCl, the effect of long-term (15 d) NaCl (70 m M) treatments on the activity and expression of the foliar ascorbate–glutathione cycle enzymes, superoxide dismutase isozymes and their mRNAs was evaluated and related to their ascorbate and glutathione contents. High-speed supernatant (soluble) fractions, enriched for cytosolic components of the antioxidant system, were used. In this fraction from the NaCl-tolerant variety (cv Granada), the activities of ascorbate peroxidase (APX), glutathione reductase (GR), monodehydroascorbate reductase (MDHAR), Mn-superoxide dismutase (Mn-SOD) and dehydroascorbate reductase (DHAR) increased, while CuZn-SOD activity remained constant. In the NaCl-sensitive plants (cv Challis), salinity did not produce significant changes in APX, MDHAR and GR activities. Only DHAR activity was induced in cv Challis, whereas soluble CuZn-SOD activity decreased by about 35%. Total ascorbate and glutathione contents decreased in both cultivars, but the decline was greater in NaCl-sensitive plants. This difference between the two cultivars was more pronounced when the transcript levels of some these enzymes were examined. Transcript levels for mitochondrial Mn-SOD, chloroplastic CuZn-SOD and phospholipid hydroperoxide glutathione peroxidase (PHGPX), cytosolic GR and APX were strongly induced in the NaCl-tolerant variety but not in the NaCl-sensitive variety. These data strongly suggest that induction of antioxidant defences is at least one component of the tolerance mechanism of peas to long-term salt-stress.

Damping pathways of mid-infrared plasmons in graphene nanostructures

Abstract: Researchers clarify damping pathways for mid-infrared graphene plasmons, including graphene intrinsic optical phonons and edge scattering. They also demonstrate the guiding of mid-infrared graphene plasmons in 50-nm-wide structures with an electromagnetic mode area of 10−3 μm2 and a propagation length of 200 nm.

Evolution of the Solar Activity over Time and Effects on Planetary Atmospheres. I. High-Energy Irradiances (1-1700 Å)

Abstract: We report on the results of the Sun in Time multiwavelength program (X-rays to UV) of solar analogs with ages covering ~0.1-7 Gyr. The chief science goals are to study the solar magnetic dynamo and to determine the radiative and magnetic properties of the Sun during its evolution across the main sequence. The present paper focuses on the latter goal, which has the ultimate purpose of providing the spectral irradiance evolution of solar-type stars to be used in the study and modeling of planetary atmospheres. The results from the Sun in Time program suggest that the coronal X-ray-EUV emissions of the young main-sequence Sun were ~100-1000 times stronger than those of the present Sun. Similarly, the transition region and chromospheric FUV-UV emissions of the young Sun are expected to be 20-60 and 10-20 times stronger, respectively, than at present. When we consider the integrated high-energy emission from 1 to 1200 A, the resulting relationship indicates that about 2.5 Gyr ago the solar high-energy flux was about 2.5 times the present value and about 3.5 Gyr ago was about 6 times the present value (when life supposedly arose on Earth). The strong radiation emissions inferred should have had major influences on the thermal structure, photochemistry, and photoionization of planetary atmospheres and have played an important role in the development of primitive life in the solar system. Some examples of the application of the Sun in Time results on exoplanets and on early solar system planets are discussed.