State University of New York System

About: State University of New York System is a education organization based out in Albany, New York, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 54077 authors who have published 78070 publications receiving 2985160 citations.

Spread of invading organisms

Abstract: D.A. Andow', P.M. Kareiva2, Simon A. Levin3 and Akira Okubo4 'Department of Entomology, University of Minnesota, St. Paul, MN 55108; 2Department of Zoology, University of Washington, Seattle, WA 98195; 3Ecosystems Research Center; Center for Environmental Research; and Section of Ecology and Systematics, Cornell University, Ithaca, N Y 14853; 4Marine Sciences Research Center, State University of New York, Stony Brook, N Y 11794; and Ecosystems Research Center, Cornell University, Ithaca, N Y

Off-line cursive script word recognition

Abstract: Cursive script word recognition is the problem of transforming a word from the iconic form of cursive writing to its symbolic form. Several component processes of a recognition system for isolated offline cursive script words are described. A word image is transformed through a hierarchy of representation levels: points, contours, features, letters, and words. A unique feature representation is generated bottom-up from the image using statistical dependences between letters and features. Ratings for partially formed words are computed using a stack algorithm and a lexicon represented as a trie. Several novel techniques for low- and intermediate-level processing for cursive script are described, including heuristics for reference line finding, letter segmentation based on detecting local minima along the lower contour and areas with low vertical profiles, simultaneous encoding of contours and their topological relationships, extracting features, and finding shape-oriented events. Experiments demonstrating the performance of the system are also described. >

Reliability, internal consistency, and validity of data obtained with the functional gait assessment.

Abstract: Background and Purpose. The Functional Gait Assessment (FGA) is a 10-item gait assessment based on the Dynamic Gait Index. The purpose of this study was to evaluate the reliability, internal consistency, and validity of data obtained with the FGA when used with people with vestibular disorders. Subjects. Seven physical therapists from various practice settings, 3 physical therapist students, and 6 patients with vestibular disorders volunteered to participate. Methods. All raters were given 10 minutes to review the instructions, the test items, and the grading criteria for the FGA. The 10 raters concurrently rated the performance of the 6 patients on the FGA. Patients completed the FGA twice, with an hour's rest between sessions. Reliability of total FGA scores was assessed using intraclass correlation coefficients (2,1). Internal consistency of the FGA was assessed using the Cronbach alpha and confirmatory factor analysis. Concurrent validity was assessed using the correlation of the FGA scores with balance and gait measurements. Results. Intraclass correlation coefficients of .86 and .74 were found for interrater and intrarater reliability of the total FGA scores. Internal consistency of the FGA scores was .79. Spearman rank order correlation coefficients of the FGA scores with balance measurements ranged from .11 to .67. Discussion and Conclusion. The FGA demonstrates what we believe is acceptable reliability, internal consistency, and concurrent validity with other balance measures used for patients with vestibular disorders.

International Union of Basic and Clinical Pharmacology. LXXV. Nomenclature, Classification, and Pharmacology of G Protein-Coupled Melatonin Receptors

Abstract: The hormone melatonin (5-methoxy- N -acetyltryptamine) is synthesized primarily in the pineal gland and retina, and in several peripheral tissues and organs. In the circulation, the concentration of melatonin follows a circadian rhythm, with high levels at night providing timing cues to target tissues endowed with melatonin receptors. Melatonin receptors receive and translate melatonin's message to influence daily and seasonal rhythms of physiology and behavior. The melatonin message is translated through activation of two G protein-coupled receptors, MT1 and MT2, that are potential therapeutic targets in disorders ranging from insomnia and circadian sleep disorders to depression, cardiovascular diseases, and cancer. This review summarizes the steps taken since melatonin's discovery by Aaron Lerner in 1958 to functionally characterize, clone, and localize receptors in mammalian tissues. The pharmacological and molecular properties of the receptors are described as well as current efforts to discover and develop ligands for treatment of a number of illnesses, including sleep disorders, depression, and cancer.