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Institution

State University of New York System

EducationAlbany, New York, United States
About: State University of New York System is a education organization based out in Albany, New York, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 54077 authors who have published 78070 publications receiving 2985160 citations.
Topics: Population, Poison control, RNA, Gene, Receptor


Papers
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Journal ArticleDOI
TL;DR: Computed microtomography is applied to a piece of Fontainebleau sandstone to determine the geometrical structure of the pores and the topology of the void space is derived from the tomographic image of the volume.
Abstract: Computed microtomography is applied to a piece of Fontainebleau sandstone in order to determine the geometrical structure of the pores. The topology of the void space is then derived from the tomographic image of the volume. Permeability and conductivity are computed and found in good agreement with experimental data. Perspectives offered by this new nondestructive method with a potential resolution of the order of one micrometer or less are analyzed.

452 citations

Journal ArticleDOI
10 Apr 2013-Neuron
TL;DR: MRI tools show that hippocampal hypermetabolism leads to atrophy in psychotic disorder and suggest glutamate as a pathogenic driver and parallel in vivo experiments showed that glutamate drives both neuroimaging abnormalities.

452 citations

Journal ArticleDOI
TL;DR: In this paper, it is shown that there is a unique boundary between solutions which exist on the whole real line and solutions which, while tending to zero at plus infinity, blow up at a finite x.
Abstract: The differential equation considered is \(y'' - xy = y|y|^\alpha \). For general positive α this equation arises in plasma physics, in work of De Boer & Ludford. For α=2, it yields similarity solutions to the well-known Korteweg-de Vries equation. Solutions are sought which satisfy the boundary conditions (1) y(∞)=0 (2) $$y{\text{(}}\infty {\text{)}} = {\text{0}}$$ (1) $$y{\text{(}}x{\text{) \~( - }}\tfrac{{\text{1}}}{{\text{2}}}x{\text{)}}^{{{\text{1}} \mathord{\left/ {\vphantom {{\text{1}} \alpha }} \right. \kern- ulldelimiterspace} \alpha }} {\text{ as }}x \to - \infty $$ (2) It is shown that there is a unique such solution, and that it is, in a certain sense, the boundary between solutions which exist on the whole real line and solutions which, while tending to zero at plus infinity, blow up at a finite x. More precisely, any solution satisfying (1) is asymptotic at plus infinity to some multiple kA i(x) of Airy's function. We show that there is a unique k*(α) such that when k=k*(α) the condition (2) is also satisfied. If 0 k* then the solution blows up at a finite x. For the special case α=2 the differential equation is classical, having been studied by Painleve around the turn of the century. In this case, using an integral equation derived by inverse scattering techniques by Ablowitz & Segur, we are able to show that k*=1, confirming previous numerical estimates.

451 citations

Journal ArticleDOI
TL;DR: Self-reported medical history and medication use in a cataract case-control study of 1,380 persons in Boston, Massachusetts, suggests an accurate recall of medical and drug usage history in well-defined chronic conditions.
Abstract: The authors compared self-reported medical history and medication use in a cataract case-control study of 1,380 persons (1985-1989) in Boston, Massachusetts, with information from the participants' physicians. Under- and overreporting varied by condition and type of medication. A self-reported history of hypertension had the highest sensitivity (91%), and diabetes history had the highest specificity (97%). Among different medications investigated, self-reported antihypertensive medication use was the most sensitive (88%), while self-reported use of insulin was the most specific (99%). Differences between patient- and physician-reported frequencies were very small, except for arthritis (15%) and regular aspirin use (21%). Results suggest an accurate recall of medical and drug usage history in well-defined chronic conditions.

449 citations

Journal ArticleDOI
TL;DR: The transition from translocation of PKC to formation of PKM may help to explain the molecular mechanisms of induction and maintenance of long-term potentiation.
Abstract: Long-term potentiation in the CA1 region of the hippocampus, a model for memory formation in the brain, is divided into two phases. A transient process (induction) is initiated, which then generates a persistent mechanism (maintenance) for enhancing synaptic strength. Protein kinase C (PKC), a gene family of multiple isozymes, may play a role in both induction and maintenance. In region CA1 from rat hippocampal slices, most of the isozymes of PKC translocated to the particulate fraction 15 sec after a tetanus. The increase of PKC in the particulate fraction did not persist into the maintenance phase of long-term potentiation. In contrast, a constitutively active kinase, PKM, a form specific to a single isozyme (zeta), increased in the cytosol during the maintenance phase. The transition from translocation of PKC to formation of PKM may help to explain the molecular mechanisms of induction and maintenance of long-term potentiation.

449 citations


Authors

Showing all 54162 results

NameH-indexPapersCitations
Meir J. Stampfer2771414283776
Bert Vogelstein247757332094
Zhong Lin Wang2452529259003
Peter Libby211932182724
Robert M. Califf1961561167961
Stephen V. Faraone1881427140298
David L. Kaplan1771944146082
David Baker1731226109377
Nora D. Volkow165958107463
David R. Holmes1611624114187
Richard J. Davidson15660291414
Ronald G. Crystal15599086680
Jovan Milosevic1521433106802
James J. Collins15166989476
Mark A. Rubin14569995640
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202325
2022168
20212,825
20202,891
20192,528
20182,456