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Institution

State University of New York System

EducationAlbany, New York, United States
About: State University of New York System is a education organization based out in Albany, New York, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 54077 authors who have published 78070 publications receiving 2985160 citations.
Topics: Population, Poison control, RNA, Gene, Receptor


Papers
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Journal ArticleDOI
TL;DR: Of various published theories of adaptive control of progeny sex ratio only two are plausible, a physiological theory by Trivers & Willard, and a demographic theory by Verner, which postulates a minimization of competition for mates in neighbourhoods subject to random fluctuation in sex ratio.
Abstract: Of various published theories of adaptive control of progeny sex ratio only two are plausible, a physiological theory by Trivers & Willard, and a demographic theory by Verner. The first applies to species in which sons and daughters impose different costs on parents, and in which only one or very few young are produced at once. They ought to show positive correlations in the sex of successive offspring and high sex-ratio variance among progenies. Verner's theory postulates a minimization of competition for mates in neighbourhoods subject to random fluctuation in sex ratio. Optimal progenies would exactly match the population's evolutionary equilibrium sex ratio. There would be little variance among progenies. Evidence from vertebrates is unfavourable to either theory and supports, instead, a non-adaptive model, the purely random (Mendelian) determination of sex. The apparent absence of parental control of progeny sex ratio is a serious theoretical difficulty.

418 citations

Journal ArticleDOI
07 Oct 1988-Cell
TL;DR: Surprisingly, removal of the H4 N terminus also derepresses the silent mating type loci, HML alpha and HMRa, disrupting mating, and this activation is specific since other regulated genes are repressed and induced normally in these cells.

418 citations

Journal ArticleDOI
TL;DR: Energy intake that exceeds energy expenditure is the main driver of weight gain and the quality of the diet may exert its effect on energy balance through complex hormonal and neurological pathways that influence satiety and possibly through other mechanisms.
Abstract: The aim of this paper is to review the evidence of the association between energy balance and obesity. In December 2015, the International Agency for Research on Cancer (IARC), Lyon, France convened a Working Group of international experts to review the evidence regarding energy balance and obesity, with a focus on Low and Middle Income Countries (LMIC). The global epidemic of obesity and the double burden, in LMICs, of malnutrition (coexistence of undernutrition and overnutrition) are both related to poor quality diet and unbalanced energy intake. Dietary patterns consistent with a traditional Mediterranean diet and other measures of diet quality can contribute to long-term weight control. Limiting consumption of sugar-sweetened beverages has a particularly important role in weight control. Genetic factors alone cannot explain the global epidemic of obesity. However, genetic, epigenetic factors and the microbiota could influence individual responses to diet and physical activity. Energy intake that exceeds energy expenditure is the main driver of weight gain. The quality of the diet may exert its effect on energy balance through complex hormonal and neurological pathways that influence satiety and possibly through other mechanisms. The food environment, marketing of unhealthy foods and urbanization, and reduction in sedentary behaviors and physical activity play important roles. Most of the evidence comes from High Income Countries and more research is needed in LMICs.

418 citations

Journal ArticleDOI
TL;DR: In this article, the overall performance of state-of-the-art atmospheric GCMs in simulating the climatological variations of summer monsoon rainfall over the Asian-western Pacific region and the systematic errors that are common to a group of GCMs were assessed.
Abstract: We assesses the overall performance of state-of-the-art atmospheric GCMs in simulating the climatological variations of summer monsoon rainfall over the Asian-Western Pacific region and the systematic errors that are common to a group of GCMs. The GCM data utilized are obtained from 10 GCM groups participated in the CLIVAR/Monsoon GCM Intercomparison Project. The model composite shows that the overall spatial pattern of summer monsoon rainfall is similar to the observed, although the western Pacific rainfall is relatively weak. For the simulated precipitation over the western Pacific, the models can be classified into two categories. The first category of models simulates the precipitation more confined to the equatorial region and weaker precipitation in the subtropical western Pacific compared to the observed. The second category of models simulates large precipitation in the subtropical western Pacific but the region is shifted to the north by 5–10°. None of the models realistically reproduce the observed Mei-yu rain band in the region from the East China Sea to the mid Pacific. Most of the models produce a rain band along the continental side of East Asia. The climatological variations of simulated summer rainfall are examined in terms of their amplitude and their principal EOF modes. All models simulate larger amplitudes of the climatological seasonal variation of Indian summer monsoon than the observed, though most models simulate smaller amplitudes in the western Pacific. The ten model composite produces four leading EOF modes over the Asian-western Pacific region, which are remarkably similar to the observed counterparts. The first and second eigenmodes, respectively, represent the smoothed seasonal march of broad-scale monsoon and the onsets of the Indian and East Asian summer monsoon. The third and fourth modes relate to the climatological intraseasonal oscillation (CISO). In contrast to the model composite, several models fail to reproduce the first principal mode, and most models do not reproduce the observed modes higher than the second. The CISO of precipitation is also examined over the Indian monsoon and the East Asia-western Pacific monsoon regions separately.

418 citations

Journal ArticleDOI
TL;DR: It is shown that the transmittances are the same for light propagation along a straight topological interface and one with four sharp turns, which quantitatively demonstrates the suppression of backscattering due to the non-trivial topology of the structure.
Abstract: Photonic topological insulators offer the possibility to eliminate backscattering losses and improve the efficiency of optical communication systems. Despite considerable efforts, a direct experimental demonstration of theoretically predicted robust, lossless energy transport in topological insulators operating at near-infrared frequencies is still missing. Here, we combine the properties of a planar silicon photonic crystal and the concept of topological protection to design, fabricate and characterize an optical topological insulator that exhibits the valley Hall effect. We show that the transmittances are the same for light propagation along a straight topological interface and one with four sharp turns. This result quantitatively demonstrates the suppression of backscattering due to the non-trivial topology of the structure. The photonic-crystal-based approach offers significant advantages compared with other realizations of photonic topological insulators, such as lower propagation losses, the presence of a band gap for light propagating in the crystal-slab plane, a larger operating bandwidth, a much smaller footprint, compatibility with complementary metal-oxide-semiconductor fabrication technology, and the fact that it allows for operation at telecommunications wavelengths.

418 citations


Authors

Showing all 54162 results

NameH-indexPapersCitations
Meir J. Stampfer2771414283776
Bert Vogelstein247757332094
Zhong Lin Wang2452529259003
Peter Libby211932182724
Robert M. Califf1961561167961
Stephen V. Faraone1881427140298
David L. Kaplan1771944146082
David Baker1731226109377
Nora D. Volkow165958107463
David R. Holmes1611624114187
Richard J. Davidson15660291414
Ronald G. Crystal15599086680
Jovan Milosevic1521433106802
James J. Collins15166989476
Mark A. Rubin14569995640
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202325
2022168
20212,825
20202,891
20192,528
20182,456