Institution
State University of New York System
Education•Albany, New York, United States•
About: State University of New York System is a education organization based out in Albany, New York, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 54077 authors who have published 78070 publications receiving 2985160 citations.
Topics: Population, Poison control, RNA, Gene, Receptor
Papers published on a yearly basis
Papers
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TL;DR: Perceptions of and reactions to stigma among 156 parents and spouses of a population-based sample of first-admission psychiatric patients are examined.
Abstract: Considerable research has documented the stigmatization of people with mental illnesses and its negative consequences. Recently it has been shown that stigma may also seriously affect families of psychiatric patients, but little empirical research has addressed this problem. We examine perceptions of and reactions to stigma among 156 parents and spouses of a population-based sample of first-admission psychiatric patients. While most family members did not perceive themselves as being avoided by others because of their relative's hospitalization, half reported concealing the hospitalization at least to some degree. Both the characteristics of the mental illness (the stigmatizing mark) and the social characteristics of the family were significantly related to levels of family stigma. Family members were more likely to conceal the mental illness if they did not live with their ill relative, if the relative was female, and if the relative had less severe positive symptoms. Family members with more education and whose relative had experienced an episode of illness within the past 6 months reported greater avoidance by others.
417 citations
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TL;DR: The identification of such factors and studies of these processes hold great promise for the future of plant biotechnology and plant genetic engineering, as they might help in the development of conceptually new techniques and approaches needed today to expand the host range of Agrobacterium.
417 citations
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16 Feb 2013TL;DR: This paper reviewed Zhu's book, "Quantitative Models for Performance Evaluation and Benchmarking: Data Envelopment Analysis with Spreadsheets,” now in its third edition and published by Springer.
Abstract: This article reviews Joe Zhu’s book, “Quantitative Models for Performance Evaluation and Benchmarking: Data Envelopment Analysis with Spreadsheets,” now in its third edition and published by Springer.
416 citations
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TL;DR: The authors analyzes the distinctive forms that collective memories take in the age of globalization, and studies the transition from national to cosmopolitan memory cultures in the cross-culture memory transfer process.
Abstract: This article analyzes the distinctive forms that collective memories take in the age of globalization. It studies the transition from national to cosmopolitan memory cultures. Cosmopolitanism refer...
416 citations
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TL;DR: In vivo treatment of mice with ongoing experimental autoimmune encephalomyelitis diminishes paralysis and progression of the disease and reduces IL-17A-secreting T cells in the periphery and central nervous system (CNS).
Abstract: A new class of inflammatory CD4(+) T cells that produce interleukin-17 (IL-17) (termed Th17) has been identified, which plays a critical role in numerous inflammatory conditions and autoimmune diseases. The active form of vitamin D, 1,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)], has a direct repressive effect on the expression of IL-17A in both human and mouse T cells. In vivo treatment of mice with ongoing experimental autoimmune encephalomyelitis (EAE; a mouse model of multiple sclerosis) diminishes paralysis and progression of the disease and reduces IL-17A-secreting CD4(+) T cells in the periphery and central nervous system (CNS). The mechanism of 1,25(OH)(2)D(3) repression of IL-17A expression was found to be transcriptional repression, mediated by the vitamin D receptor (VDR). Transcription assays, gel shifting, and chromatin immunoprecipitation (ChIP) assays indicate that the negative effect of 1,25(OH)(2)D(3) on IL-17A involves blocking of nuclear factor for activated T cells (NFAT), recruitment of histone deacetylase (HDAC), sequestration of Runt-related transcription factor 1 (Runx1) by 1,25(OH)(2)D(3)/VDR, and a direct effect of 1,25(OH)(2)D(3) on induction of Foxp3. Our results describe novel mechanisms and new concepts with regard to vitamin D and the immune system and suggest therapeutic targets for the control of autoimmune diseases.
416 citations
Authors
Showing all 54162 results
Name | H-index | Papers | Citations |
---|---|---|---|
Meir J. Stampfer | 277 | 1414 | 283776 |
Bert Vogelstein | 247 | 757 | 332094 |
Zhong Lin Wang | 245 | 2529 | 259003 |
Peter Libby | 211 | 932 | 182724 |
Robert M. Califf | 196 | 1561 | 167961 |
Stephen V. Faraone | 188 | 1427 | 140298 |
David L. Kaplan | 177 | 1944 | 146082 |
David Baker | 173 | 1226 | 109377 |
Nora D. Volkow | 165 | 958 | 107463 |
David R. Holmes | 161 | 1624 | 114187 |
Richard J. Davidson | 156 | 602 | 91414 |
Ronald G. Crystal | 155 | 990 | 86680 |
Jovan Milosevic | 152 | 1433 | 106802 |
James J. Collins | 151 | 669 | 89476 |
Mark A. Rubin | 145 | 699 | 95640 |