Institution
State University of New York System
Education•Albany, New York, United States•
About: State University of New York System is a education organization based out in Albany, New York, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 54077 authors who have published 78070 publications receiving 2985160 citations.
Topics: Population, Poison control, RNA, Gene, Receptor
Papers published on a yearly basis
Papers
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01 Jul 2019TL;DR: In this paper, the authors highlight breakthroughs, challenges and future directions for both platinum group metal (PGM) and PGM-free ORR cathode catalysts, and highlight the important role of carbon supports in enhancing overall performance.
Abstract: Proton exchange membrane fuel cells can use hydrogen and air to power clean electric vehicles. However, technical barriers including high cost, limited lifetime and insufficient power density limit their broad applications. Advanced cathode catalysts for the kinetically-sluggish oxygen reduction reaction (ORR) in acidic media are essential for overcoming these barriers. Here, we highlight breakthroughs, challenges and future directions for both platinum group metal (PGM) and PGM-free ORR cathode catalysts. Among PGM catalysts, highly-ordered PtM intermetallic nanostructures exhibit enhanced activity and stability relative to PtM random alloys. Carbon supports, with optimal balance between graphitization degree and porosity, play an important role in enhancing overall performance. Among PGM-free catalysts, transition metal and nitrogen co-doped carbons (M-N-C) perform best. However, degradation at practical voltages (>0.6 V) still prevents their practical application. For all catalysts, translating intrinsic activity and stability into device performance requires electrodes with robust three-phase interfaces for effective charge and mass transfer. Proton exchange membrane fuel cells can efficiently provide clean power for electric vehicles, although more efficient and economic cathode catalysts are still required. This Review highlights recent breakthroughs, challenges and future research directions for Pt group metal (PGM) and PGM-free oxygen reduction catalysts.
629 citations
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TL;DR: Hemodynamics is as important as morphology in discriminating aneurysm rupture status with high AUC values, and all 3 models—morphological only, hemodynamic only, and combined—discriminate intracranial aneurYSm rupturestatus with highAUC values.
Abstract: Background and purpose the purpose of this study was to identify significant morphological and hemodynamic parameters that discriminate intracranial aneurysm rupture status using 3-dimensional angiography and computational fluid dynamics. Methods one hundred nineteen intracranial aneurysms (38 ruptured, 81 unruptured) were analyzed from 3-dimensional angiographic images and computational fluid dynamics. Six morphological and 7 hemodynamic parameters were evaluated for significance with respect to rupture. Receiver operating characteristic analysis identified area under the curve (AUC) and optimal thresholds separating ruptured from unruptured aneurysms for each parameter. Significant parameters were examined by multivariate logistic regression analysis in 3 predictive models-morphology only, hemodynamics only, and combined-to identify independent discriminants, and the AUC receiver operating characteristic of the predicted probability of rupture status was compared among these models. Results morphological parameters (size ratio, undulation index, ellipticity index, and nonsphericity index) and hemodynamic parameters (average wall shear stress [WSS], maximum intra-aneurysmal WSS, low WSS area, average oscillatory shear index, number of vortices, and relative resident time) achieved statistical significance (P Conclusions all 3 models-morphological (based on size ratio), hemodynamic (based on WSS and oscillatory shear index), and combined-discriminate intracranial aneurysm rupture status with high AUC values. Hemodynamics is as important as morphology in discriminating aneurysm rupture status.
628 citations
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TL;DR: In this article, it is suggested that the observed variations are a consequence of dynamic partial melting of a homogeneous mantle source region, which may be generated by processes in the mantle during melting.
627 citations
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26 Sep 2011TL;DR: This paper aims to fill the research gap by building a comprehensive framework to view the smart city movement as innovation comprised of technology, management and policy.
Abstract: This paper sees a smart city not as a status of how smart a city is but as a city's effort to make itself smart. The connotation of a smart city represents city innovation in management and policy as well as technology. Since the unique context of each city shapes the technological, organizational and policy aspects of that city, a smart city can be considered a contextualized interplay among technological innovation, managerial and organizational innovation, and policy innovation. However, only little research discusses innovation in management and policy while the literature of technology innovation is abundant. This paper aims to fill the research gap by building a comprehensive framework to view the smart city movement as innovation comprised of technology, management and policy. We also discuss inevitable risks from innovation, strategies to innovate while avoiding risks, and contexts underlying innovation and risks.
626 citations
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TL;DR: Novel and biocompatible core/shell (α-NaYbF(4):Tm(3+))/CaF(2) nanoparticles that exhibit highly efficient NIR(in)-NIR(out) upconversion (UC) for high contrast and deep bioimaging are described.
Abstract: We describe the development of novel and biocompatible core/shell (α-NaYbF(4):Tm(3+))/CaF(2) nanoparticles that exhibit highly efficient NIR(in)-NIR(out) upconversion (UC) for high contrast and deep bioimaging. When excited at ~980 nm, these nanoparticles emit photoluminescence (PL) peaked at ~800 nm. The quantum yield of this UC PL under low power density excitation (~0.3 W/cm(2)) is 0.6 ± 0.1%. This high UC PL efficiency is realized by suppressing surface quenching effects via heteroepitaxial growth of a biocompatible CaF(2) shell, which results in a 35-fold increase in the intensity of UC PL from the core. Small-animal whole-body UC PL imaging with exceptional contrast (signal-to-background ratio of 310) is shown using BALB/c mice intravenously injected with aqueously dispersed nanoparticles (700 pmol/kg). High-contrast UC PL imaging of deep tissues is also demonstrated, using a nanoparticle-loaded synthetic fibrous mesh wrapped around rat femoral bone and a cuvette with nanoparticle aqueous dispersion covered with a 3.2 cm thick animal tissue (pork).
625 citations
Authors
Showing all 54162 results
Name | H-index | Papers | Citations |
---|---|---|---|
Meir J. Stampfer | 277 | 1414 | 283776 |
Bert Vogelstein | 247 | 757 | 332094 |
Zhong Lin Wang | 245 | 2529 | 259003 |
Peter Libby | 211 | 932 | 182724 |
Robert M. Califf | 196 | 1561 | 167961 |
Stephen V. Faraone | 188 | 1427 | 140298 |
David L. Kaplan | 177 | 1944 | 146082 |
David Baker | 173 | 1226 | 109377 |
Nora D. Volkow | 165 | 958 | 107463 |
David R. Holmes | 161 | 1624 | 114187 |
Richard J. Davidson | 156 | 602 | 91414 |
Ronald G. Crystal | 155 | 990 | 86680 |
Jovan Milosevic | 152 | 1433 | 106802 |
James J. Collins | 151 | 669 | 89476 |
Mark A. Rubin | 145 | 699 | 95640 |