Institution
Sun Yat-sen University
Education•Guangzhou, Guangdong, China•
About: Sun Yat-sen University is a education organization based out in Guangzhou, Guangdong, China. It is known for research contribution in the topics: Population & Cancer. The organization has 115149 authors who have published 113763 publications receiving 2286465 citations. The organization is also known as: Zhongshan University & SYSU.
Topics: Population, Cancer, Medicine, Cell growth, Metastasis
Papers published on a yearly basis
Papers
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TL;DR: The electrocatalytic oxygen evolution reaction (OER) is a core reaction responsible for converting renewable electricity into storable fuels; yet, it is kinetically challenging, because of the complex complex OER as discussed by the authors.
Abstract: Electrocatalytic oxygen evolution reaction (OER) is a core reaction responsible for converting renewable electricity into storable fuels; yet, it is kinetically challenging, because of the complex ...
315 citations
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Fred Hutchinson Cancer Research Center1, University of Washington2, University of Southern California3, University of North Carolina at Chapel Hill4, National Institutes of Health5, University of Nantes6, German Cancer Research Center7, Kaiser Permanente8, American Cancer Society9, Harvard University10, University of Chicago11, Translational Genomics Research Institute12, Vanderbilt University13, University of Toronto14, New York University15, University of Melbourne16, Ontario Institute for Cancer Research17, Ohio State University18, Yonsei University19, Sun Yat-sen University20, University of Hawaii at Manoa21, Mayo Clinic22, Massey University23, Yeshiva University24, University of Pittsburgh25, University of Utah26, Fudan University27, University of Ottawa28
TL;DR: In a large genome-wide association study, polymorphisms close to nucleic acid binding protein 1 (which encodes a DNA-binding protein involved in DNA repair) with colorectal tumor risk and polymorphisms in laminin gamma 1, cyclin D2, and T-box 3 are associated.
314 citations
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TL;DR: A comprehensive landscape of the transcriptome profiles of 14 primary prostate cancers and their paired normal counterparts from the Chinese population using RNA-seq reveals tremendous diversity across prostate cancer transcriptomes with respect to gene fusions, long noncoding RNAs (long ncRNA), alternative splicing and somatic mutations.
Abstract: There are remarkable disparities among patients of different races with prostate cancer; however, the mechanism underlying this difference remains unclear. Here, we present a comprehensive landscape of the transcriptome profiles of 14 primary prostate cancers and their paired normal counterparts from the Chinese population using RNA-seq, revealing tremendous diversity across prostate cancer transcriptomes with respect to gene fusions, long noncoding RNAs (long ncRNA), alternative splicing and somatic mutations. Three of the 14 tumors (21.4%) harbored a TMPRSS2-ERG fusion, and the low prevalence of this fusion in Chinese patients was further confirmed in an additional tumor set (10/54=18.5%). Notably, two novel gene fusions, CTAGE5-KHDRBS3 (20/54=37%) and USP9Y-TTTY15 (19/54=35.2%), occurred frequently in our patient cohort. Further systematic transcriptional profiling identified numerous long ncRNAs that were differentially expressed in the tumors. An analysis of the correlation between expression of long ncRNA and genes suggested that long ncRNAs may have functions beyond transcriptional regulation. This study yielded new insights into the pathogenesis of prostate cancer in the Chinese population.
314 citations
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TL;DR: The rapid loss of native mammals from isolated Thai forests suggests that forest fragments cannot maintain biodiversity, and small fragments are potentially even more vulnerable to biodiversity loss than previously thought.
Abstract: Tropical forests continue to be felled and fragmented around the world. A key question is how rapidly species disappear from forest fragments and how quickly humans must restore forest connectivity to minimize extinctions. We surveyed small mammals on forest islands in Chiew Larn Reservoir in Thailand 5 to 7 and 25 to 26 years after isolation and observed the near-total loss of native small mammals within 5 years from <10-hectare (ha) fragments and within 25 years from 10- to 56-ha fragments. Based on our results, we developed an island biogeographic model and estimated mean extinction half-life (50% of resident species disappearing) to be 13.9 years. These catastrophic extinctions were probably partly driven by an invasive rat species; such biotic invasions are becoming increasingly common in human-modified landscapes. Our results are thus particularly relevant to other fragmented forest landscapes and suggest that small fragments are potentially even more vulnerable to biodiversity loss than previously thought.
314 citations
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TL;DR: Dye-sensitized solar cells based on the hierarchical anatase TiO2 nano-architecture array photoelectrode of 18 μm in length shows a power conversion efficiency of 7.34% because of its higher specific surface area for adsorbing more dye molecules and superior light scattering capacity for boosting the light-harvesting efficiency.
Abstract: Hierarchical anatase TiO2 nano-architecture arrays consisting of long TiO2 nanowire trunk and numerous short TiO2 nanorod branches on transparent conductive fluorine-doped tin oxide glass are successfully synthesized for the first time through a facile one-step hydrothermal route without any surfactant and template Dye-sensitized solar cells based on the hierarchical anatase TiO2 nano-architecture array photoelectrode of 18 μm in length shows a power conversion efficiency of 734% because of its higher specific surface area for adsorbing more dye molecules and superior light scattering capacity for boosting the light-harvesting efficiency The present photovoltaic performance is the highest value for the reported TiO2 nanowires array photoelectrode
314 citations
Authors
Showing all 115971 results
Name | H-index | Papers | Citations |
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Yi Chen | 217 | 4342 | 293080 |
Jing Wang | 184 | 4046 | 202769 |
Yang Gao | 168 | 2047 | 146301 |
Yang Yang | 164 | 2704 | 144071 |
Peter Carmeliet | 164 | 844 | 122918 |
Frank J. Gonzalez | 160 | 1144 | 96971 |
Xiang Zhang | 154 | 1733 | 117576 |
Rui Zhang | 151 | 2625 | 107917 |
Seeram Ramakrishna | 147 | 1552 | 99284 |
Joseph J.Y. Sung | 142 | 1240 | 92035 |
Joseph Lau | 140 | 1048 | 99305 |
Bin Liu | 138 | 2181 | 87085 |
Georgios B. Giannakis | 137 | 1321 | 73517 |
Kwok-Yung Yuen | 137 | 1173 | 100119 |
Shu Li | 136 | 1001 | 78390 |