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Institution

Sun Yat-sen University

EducationGuangzhou, Guangdong, China
About: Sun Yat-sen University is a education organization based out in Guangzhou, Guangdong, China. It is known for research contribution in the topics: Population & Cancer. The organization has 115149 authors who have published 113763 publications receiving 2286465 citations. The organization is also known as: Zhongshan University & SYSU.
Topics: Population, Cancer, Metastasis, Cell growth, Apoptosis


Papers
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Proceedings ArticleDOI
TL;DR: Zhang et al. as mentioned in this paper proposed a triplet ranking loss to characterize that one image is more similar to the second image than to the third one, which achieved state-of-the-art performance.
Abstract: Similarity-preserving hashing is a widely-used method for nearest neighbour search in large-scale image retrieval tasks. For most existing hashing methods, an image is first encoded as a vector of hand-engineering visual features, followed by another separate projection or quantization step that generates binary codes. However, such visual feature vectors may not be optimally compatible with the coding process, thus producing sub-optimal hashing codes. In this paper, we propose a deep architecture for supervised hashing, in which images are mapped into binary codes via carefully designed deep neural networks. The pipeline of the proposed deep architecture consists of three building blocks: 1) a sub-network with a stack of convolution layers to produce the effective intermediate image features; 2) a divide-and-encode module to divide the intermediate image features into multiple branches, each encoded into one hash bit; and 3) a triplet ranking loss designed to characterize that one image is more similar to the second image than to the third one. Extensive evaluations on several benchmark image datasets show that the proposed simultaneous feature learning and hash coding pipeline brings substantial improvements over other state-of-the-art supervised or unsupervised hashing methods.

555 citations

Journal ArticleDOI
TL;DR: A well-dated, pollen-based, ~20-yr-resolution quantitative precipitation reconstruction from an alpine lake in North China, which provides for the first time a direct record of EASM evolution since 14.7 ka, points to strong internal feedback processes driving the EASm, and may aid the understanding of future monsoon behaviour under ongoing anthropogenic climate change.
Abstract: The lack of a precisely-dated, unequivocal climate proxy from northern China, where precipitation variability is traditionally considered as an East Asian summer monsoon (EASM) indicator, impedes our understanding of the behaviour and dynamics of the EASM. Here we present a well-dated, pollen-based, ~20-yr-resolution quantitative precipitation reconstruction (derived using a transfer function) from an alpine lake in North China, which provides for the first time a direct record of EASM evolution since 14.7 ka (ka = thousands of years before present, where the "present" is defined as the year AD 1950). Our record reveals a gradually intensifying monsoon from 14.7-7.0 ka, a maximum monsoon (30% higher precipitation than present) from ~7.8-5.3 ka, and a rapid decline since ~3.3 ka. These insolation-driven EASM trends were punctuated by two millennial-scale weakening events which occurred synchronously to the cold Younger Dryas and at ~9.5-8.5 ka, and by two centennial-scale intervals of enhanced (weakened) monsoon during the Medieval Warm Period (Little Ice Age). Our precipitation reconstruction, consistent with temperature changes but quite different from the prevailing view of EASM evolution, points to strong internal feedback processes driving the EASM, and may aid our understanding of future monsoon behaviour under ongoing anthropogenic climate change.

554 citations

Journal ArticleDOI
01 Aug 2019-ACS Nano
TL;DR: In this review, recent significant research developments of PDA including its synthesis and polymerization mechanism, physicochemical properties, different nano/micro-structures and diverse applications are summarized and discussed.
Abstract: As a mussel-inspired material, polydopamine (PDA), possesses many properties, such as a simple preparation process, good biocompatibility, strong adhesive property, easy functionalization, outstanding photothermal conversion efficiency, and strong quenching effect. PDA has attracted increasingly considerable attention because it provides a simple and versatile approach to functionalize material surfaces for obtaining a variety of multifunctional nanomaterials. In this review, recent significant research developments of PDA including its synthesis and polymerization mechanism, physicochemical properties, different nano/microstructures, and diverse applications are summarized and discussed. For the sections of its applications in surface modification and biomedicine, we mainly highlight the achievements in the past few years (2016-2019). The remaining challenges and future perspectives of PDA-based nanoplatforms are discussed rationally at the end. This timely and overall review should be desirable for a wide range of scientists and facilitate further development of surface coating methods and the production of PDA-based materials.

552 citations

Journal ArticleDOI
TL;DR: Recurrent implantation failure refers to failure to achieve a clinical pregnancy after transfer of at least four good-quality embryos in a minimum of three fresh or frozen cycles in a woman under the age of 40 years.
Abstract: Recurrent implantation failure refers to failure to achieve a clinical pregnancy after transfer of at least four good-quality embryos in a minimum of three fresh or frozen cycles in a woman under the age of 40years. The failure to implant may be a consequence of embryo or uterine factors. Thorough investigations should be carried out to ascertain whether there is any underlying cause of the condition. Ovarian function should be assessed by measurement of antral follicle count, FSH and anti-Mullerian hormone. Increased sperm DNA fragmentation may be a contributory cause. Various uterine pathology including fibroids, endometrial polyps, congenital anomalies and intrauterine adhesions should be excluded by ultrasonography and hysteroscopy. Hydrosalpinges are a recognized cause of implantation failure and should be excluded by hysterosalpingogram; if necessary, laparoscopy should be performed to confirm or refute the diagnosis. Treatment offered should be evidence based, aimed at improving embryo quality or endometrial receptivity. Gamete donation or surrogacy may be necessary if there is no realistic chance of success with further IVF attempts. Recurrent implantation failure is an important cause of repeated IVF failure. It is estimated that approximately 10% of women seeking IVF treatment will experience this particular problem. It is a distressing condition for patients and frustrating for clinicians and scientists. In this review, we have discussed the definition and management of the possible underlying causes of recurrent implantation failure.

552 citations

Journal ArticleDOI
TL;DR: Combining increased time outdoors in schools, to slow the onset of myopia, with clinical methods for slowing myopic progression, should lead to the control of this epidemic, which would otherwise pose a major health challenge.

551 citations


Authors

Showing all 115971 results

NameH-indexPapersCitations
Yi Chen2174342293080
Jing Wang1844046202769
Yang Gao1682047146301
Yang Yang1642704144071
Peter Carmeliet164844122918
Frank J. Gonzalez160114496971
Xiang Zhang1541733117576
Rui Zhang1512625107917
Seeram Ramakrishna147155299284
Joseph J.Y. Sung142124092035
Joseph Lau140104899305
Bin Liu138218187085
Georgios B. Giannakis137132173517
Kwok-Yung Yuen1371173100119
Shu Li136100178390
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20241
2023349
20221,547
202115,594
202013,929
201911,766