Sungkyunkwan University

About: Sungkyunkwan University is a education organization based out in Seoul, South Korea. It is known for research contribution in the topics: Thin film & Graphene. The organization has 28229 authors who have published 56428 publications receiving 1352733 citations. The organization is also known as: 성균관대학교.

Phase III Trial Comparing Capecitabine Plus Cisplatin Versus Capecitabine Plus Cisplatin With Concurrent Capecitabine Radiotherapy in Completely Resected Gastric Cancer With D2 Lymph Node Dissection: The ARTIST Trial

Abstract: Purpose The ARTIST (Adjuvant Chemoradiation Therapy in Stomach Cancer) trial was the first study to our knowledge to investigate the role of postoperative chemoradiotherapy therapy in patients with curatively resected gastric cancer with D2 lymph node dissection. This trial was designed to compare postoperative treatment with capecitabine plus cisplatin (XP) versus XP plus radiotherapy with capecitabine (XP/XRT/XP). Patients and Methods The XP arm received six cycles of XP (capecitabine 2,000 mg/m 2 per day on days 1 to 14 and cisplatin 60 mg/m 2 on day 1, repeated every 3 weeks) chemotherapy. The XP/XRT/XP arm received two cycles of XP followed by 45-Gy XRT (capecitabine 1,650 mg/m 2 per day for 5 weeks) and two cycles of XP. Results Of 458 patients, 228 were randomly assigned to the XP arm and 230 to the XP/XRT/XP arm. Treatment was completed as planned by 75.4% of patients (172 of 228) in the XP arm and 81.7% (188 of 230) in the XP/XRT/XP arm. Overall, the addition of XRT to XP chemotherapy did not significantly prolong disease-free survival (DFS; P .0862). However, in the subgroup of patients with pathologic lymph node metastasis at the time of surgery (n 396), patients randomly assigned to the XP/XRT/XP arm experienced superior DFS when compared with those who received XP alone (P .0365), and the statistical significance was retained at multivariate analysis (estimated hazard ratio, 0.6865; 95% CI, 0.4735 to 0.9952; P .0471). Conclusion The addition of XRT to XP chemotherapy did not significantly reduce recurrence after curative resection and D2 lymph node dissection in gastric cancer. A subsequent trial (ARTIST-II) in patients with lymph node–positive gastric cancer is planned. J Clin Oncol 30:268-273. © 2011 by American Society of Clinical Oncology

Toward Smart Wireless Communications via Intelligent Reflecting Surfaces: A Contemporary Survey

Abstract: This paper presents a literature review on recent applications and design aspects of the intelligent reflecting surface (IRS) in the future wireless networks. Conventionally, the network optimization has been limited to transmission control at two endpoints, i.e., end users and network controller. The fading wireless channel is uncontrollable and becomes one of the main limiting factors for performance improvement. The IRS is composed of a large array of scattering elements, which can be individually configured to generate additional phase shifts to the signal reflections. Hence, it can actively control the signal propagation properties in favor of signal reception, and thus realize the notion of a smart radio environment. As such, the IRS’s phase control, combined with the conventional transmission control, can potentially bring performance gain compared to wireless networks without IRS. In this survey, we first introduce basic concepts of the IRS and the realizations of its reconfigurability. Then, we focus on applications of the IRS in wireless communications. We overview different performance metrics and analytical approaches to characterize the performance improvement of IRS-assisted wireless networks. To exploit the performance gain, we discuss the joint optimization of the IRS’s phase control and the transceivers’ transmission control in different network design problems, e.g., rate maximization and power minimization problems. Furthermore, we extend the discussion of IRS-assisted wireless networks to some emerging use cases. Finally, we highlight important practical challenges and future research directions for realizing IRS-assisted wireless networks in beyond 5G communications.

Avelumab Maintenance Therapy for Advanced or Metastatic Urothelial Carcinoma

Abstract: Background Platinum-based chemotherapy is standard-of-care first-line treatment for advanced urothelial carcinoma. However, progression-free survival and overall survival are limited by ch...

Universal Approach toward Hysteresis-Free Perovskite Solar Cell via Defect Engineering

Abstract: Organic–inorganic halide perovskite is believed to be a potential candidate for high efficiency solar cells because power conversion efficiency (PCE) was certified to be more than 22%. Nevertheless, mismatch of PCE due to current density (J)–voltage (V) hysteresis in perovskite solar cells is an obstacle to overcome. There has been much lively debate on the origin of J–V hysteresis; however, effective methodology to solve the hysteric problem has not been developed. Here we report a universal approach for hysteresis-free perovskite solar cells via defect engineering. A severe hysteresis observed from the normal mesoscopic structure employing TiO2 and spiro-MeOTAD is almost removed or does not exist upon doping the pure perovskites, CH3NH3PbI3 and HC(NH2)2PbI3, and the mixed cation/anion perovskites, FA0.85MA0.15PbI2.55Br0.45 and FA0.85MA0.1Cs0.05PbI2.7Br0.3, with potassium iodide. Substantial reductions in low-frequency capacitance and bulk trap density are measured from the KI-doped perovskite, which is ...

Ultrasonography Diagnosis and Imaging-Based Management of Thyroid Nodules: Revised Korean Society of Thyroid Radiology Consensus Statement and Recommendations

Abstract: The rate of detection of thyroid nodules and carcinomas has increased with the widespread use of ultrasonography (US), which is the mainstay for the detection and risk stratification of thyroid nodules as well as for providing guidance for their biopsy and nonsurgical treatment. The Korean Society of Thyroid Radiology (KSThR) published their first recommendations for the US-based diagnosis and management of thyroid nodules in 2011. These recommendations have been used as the standard guidelines for the past several years in Korea. Lately, the application of US has been further emphasized for the personalized management of patients with thyroid nodules. The Task Force on Thyroid Nodules of the KSThR has revised the recommendations for the ultrasound diagnosis and imaging-based management of thyroid nodules. The review and recommendations in this report have been based on a comprehensive analysis of the current literature and the consensus of experts.