Institution
Tallinn University of Technology
Education•Tallinn, Estonia•
About: Tallinn University of Technology is a education organization based out in Tallinn, Estonia. It is known for research contribution in the topics: European union & Computer science. The organization has 3688 authors who have published 10313 publications receiving 145058 citations. The organization is also known as: Tallinn Technical University & Tallinna Tehnikaülikool.
Topics: European union, Computer science, Oil shale, Nonlinear system, Thin film
Papers published on a yearly basis
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TL;DR: In this article, the importance of service quality as a tool to enhance customer engagement remains under-explored, as addressed in this study, and the results reveal a positive effect of Service Quality on customer engagement, which consequently exerts a favorable impact on brand experience and repatronage intent.
178 citations
Queen Mary University of London1, Medical Research Council2, King's College London3, University of Glasgow4, Glenfield Hospital5, University of Leicester6, University College London7, University of Ioannina8, Imperial College London9, University College Dublin10, St George's, University of London11, University of Cambridge12, University of Dundee13, Centre for Mental Health14, University of Edinburgh15, University of Michigan16, Health Protection Agency17, University Medical Center Groningen18, University of Sassari19, Mount Carmel Health20, University of Milan21, Katholieke Universiteit Leuven22, French Institute of Health and Medical Research23, Paris Descartes University24, University of Tartu25, Tallinn University of Technology26, University of Gothenburg27, University of Oslo28, Lund University29, University of Ottawa30, Clinical Trial Service Unit31, Wellcome Trust Centre for Human Genetics32, John Radcliffe Hospital33, Karolinska University Hospital34, University of Münster35, Wellcome Trust Sanger Institute36, University of London37, GlaxoSmithKline38, AstraZeneca39, Harvard University40, Royal College of Surgeons in Ireland41
TL;DR: An analysis of combined discovery and follow-up data identified SNPs significantly associated with BP at p < 8.56 × 10(-7) at four further loci and highlighted the utility of studying SNPs and samples that are independent of those studied previously even when the sample size is smaller than that in previous studies.
Abstract: Raised blood pressure (BP) is a major risk factor for cardiovascular disease. Previous studies have identified 47 distinct genetic variants robustly associated with BP, but collectively these explain only a few percent of the heritability for BP phenotypes. To find additional BP loci, we used a bespoke gene-centric array to genotype an independent discovery sample of 25,118 individuals that combined hypertensive case-control and general population samples. We followed up four SNPs associated with BP at our p < 8.56 × 10(-7) study-specific significance threshold and six suggestively associated SNPs in a further 59,349 individuals. We identified and replicated a SNP at LSP1/TNNT3, a SNP at MTHFR-NPPB independent (r(2) = 0.33) of previous reports, and replicated SNPs at AGT and ATP2B1 reported previously. An analysis of combined discovery and follow-up data identified SNPs significantly associated with BP at p < 8.56 × 10(-7) at four further loci (NPR3, HFE, NOS3, and SOX6). The high number of discoveries made with modest genotyping effort can be attributed to using a large-scale yet targeted genotyping array and to the development of a weighting scheme that maximized power when meta-analyzing results from samples ascertained with extreme phenotypes, in combination with results from nonascertained or population samples. Chromatin immunoprecipitation and transcript expression data highlight potential gene regulatory mechanisms at the MTHFR and NOS3 loci. These results provide candidates for further study to help dissect mechanisms affecting BP and highlight the utility of studying SNPs and samples that are independent of those studied previously even when the sample size is smaller than that in previous studies.
178 citations
TL;DR: Suggestions for future development of the open source energy system model Balmorel are outlined, such as including transport of local biomass as part of the optimisation and speeding up the model.
177 citations
TL;DR: In this paper, total phenolic content and DPPH radical scavenging capability of the bran layer, flour made from endosperm and whole grain of wheat were determined.
175 citations
TL;DR: The widespread expression of MANF together with its evolutionary conserved nature and regulation by brain insults suggest that it has important functions both under normal and pathological conditions in many tissue types.
174 citations
Authors
Showing all 3757 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| James Chapman | 82 | 483 | 36468 |
| Alexandre Alexakis | 67 | 540 | 17247 |
| Bernard Waeber | 56 | 370 | 35335 |
| Peter A. Andrekson | 54 | 573 | 12042 |
| Charles S. Peirce | 51 | 167 | 11998 |
| Lars M. Blank | 49 | 301 | 8011 |
| Fushuan Wen | 49 | 465 | 9189 |
| Mati Karelson | 48 | 207 | 10210 |
| Ago Samoson | 46 | 119 | 8807 |
| Zebo Peng | 45 | 359 | 7312 |
| Petru Eles | 44 | 300 | 6749 |
| Vijai Kumar Gupta | 43 | 301 | 6901 |
| Eero Vasar | 43 | 263 | 6930 |
| Rik Ossenkoppele | 42 | 192 | 6839 |
| Tõnis Timmusk | 41 | 105 | 11056 |