Tallinn University of Technology

About: Tallinn University of Technology is a education organization based out in Tallinn, Estonia. It is known for research contribution in the topics: European union & Oil shale. The organization has 3688 authors who have published 10313 publications receiving 145058 citations. The organization is also known as: Tallinn Technical University & Tallinna Tehnikaülikool.

Risk management in public procurement for innovation: the case of Nordic–Baltic Sea cities

Abstract: State support for innovation in enterprises has been long-standing. One of the specific support measures is public procurement for innovation, which has only recently re-emerged in academic discussion as well as in the European policy discourse. While the spillovers from this type of innovation policy measure may be substantial, the complex processes underlying the support for innovation through public procurement are associated with high risks. We take an exploratory approach to determine the state of practice of risk management in public procurement for innovation at the local level. Five case studies, which were selected as representative cases of the Nordic–Baltic Sea region in Europe, were analyzed. We found that the cities were, for the most part, actively involved in risk identification; the risks are primarily being met with mixed contracting strategies rather than comprehensive risk management tools.

Workplace bullying and organizational culture in a post‐transitional country

Abstract: Purpose – The aim of the study is to explore how organizational culture influences occurrences of workplace bullying in Estonia as a post‐transitional country. Another objective is to produce comprehensive empirical evidence of bullying in the specific cultural context.Design/methodology/approach – The survey is based on the internationally well‐known research instrument, the Negative Acts Questionnaire Revised (NAQ‐R) (Mikkelsen and Einarsen) and the Questionnaire of Organizational Culture (QOC) (Vadi et al.).Findings – Victims of bullying: 22 percent – at least one negative act per week; 9.3 percent – at least two negative acts per week; 0.6 percent – by definition (several times per week or daily); 8 percent – by definition (occasionally). The results reveal a clear negative relationship between bullying and task and relationship orientation of organizational culture.Practical implications – The present study indicates clear factors at the organizational level where the preventive actions are needed to...

Exploring the Conserved Role of MANF in the Unfolded Protein Response in Drosophila melanogaster.

Abstract: Disturbances in the homeostasis of endoplasmic reticulum (ER) referred to as ER stress is involved in a variety of human diseases. ER stress activates unfolded protein response (UPR), a cellular mechanism the purpose of which is to restore ER homeostasis. Previous studies show that Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) is an important novel component in the regulation of UPR. In vertebrates, MANF is upregulated by ER stress and protects cells against ER stress-induced cell death. Biochemical studies have revealed an interaction between mammalian MANF and GRP78, the major ER chaperone promoting protein folding. In this study we discovered that the upregulation of MANF expression in response to drug-induced ER stress is conserved between Drosophila and mammals. Additionally, by using a genetic in vivo approach we found genetic interactions between Drosophila Manf and genes encoding for Drosophila homologues of GRP78, PERK and XBP1, the key components of UPR. Our data suggest a role for Manf in the regulation of Drosophila UPR.