scispace - formally typeset
Search or ask a question
Institution

Tata Memorial Hospital

HealthcareMumbai, India
About: Tata Memorial Hospital is a healthcare organization based out in Mumbai, India. It is known for research contribution in the topics: Cancer & Breast cancer. The organization has 3187 authors who have published 4636 publications receiving 109143 citations.


Papers
More filters
Journal Article
TL;DR: In spite of appreciable knowledge about cancer, creating awareness about screening, its availability, and motivating the general population for screening is necessary.
Abstract: Background Cancer, a major cause of morbidity and mortality in India can be prevented by early detection through screening, for which, awareness is essential. Aim Determining cancer awareness among low socioeconomic women in Mumbai. Settings and design Community based cancer screening study using a mobile van. Materials and methods Data of consenting participants, collected using structured questionnaire, was differentiated into good and poor level of awareness using point based grading procedure. results: Mean age of 182 participants, majority (90.5%) belonging to lower socioeconomic strata, was 43.0∓8.8 years. Knowledge about cancer (84.6%) was good compared to knowledge of cancer screening (35.1%), awareness being higher among richer and more educated. Major sources of information were friends or relatives (46.1%) and media (35.2%). Only 6.6% had undergone prior screening. Conclusion In spite of appreciable knowledge about cancer, creating awareness about screening, its availability, and motivating the general population for screening is necessary.

26 citations

Journal ArticleDOI
TL;DR: Significantly prolonged disease-free survival was seen in patients who received ATRA with chemotherapy, and ATRA was well-tolerated by these patients.
Abstract: Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloblastic leukemia (AML). In this report, we present the clinical features, management, and outcome of pediatric patients with APL treated with all-trans-retinoic acid (ATRA). Of 52 newly diagnosed cases of APL between February 1992 and December 1996, 15 were in the pediatric age group (younger than 15 years). Four patients were treated with ATRA alone and 11 were allocated to receive ATRA followed by chemotherapy. Eighty-six percent of the patients achieved a complete response. The patients who received ATRA alone as maintenance therapy had relapses with a median duration of remission of 8 months (range 6-12). The patients who received ATRA, followed by consolidation chemotherapy, had a prolonged duration of remission, with a median of 20 months (range 13-28). In addition, rapid correction of coagulopathy was observed in these patients. The median duration for correction of coagulopathy was 7 days (range 5-11) and the median duration for recovery from neutropenia after chemotherapy was 10 days (range 7-20). Two major side effects of ATRA were hyperleukocytosis and retinoic acid syndrome. Significantly prolonged disease-free survival was seen in patients who received ATRA with chemotherapy. APL is not uncommon in the pediatric age group. ATRA was well-tolerated by these patients. Consolidation with chemotherapy helps in prolonging the disease-free survival in patients with APL in comparison to treatment with ATRA alone.

26 citations

Journal ArticleDOI
TL;DR: Investigating the EBV-association in paired samples of cHD obtained at presentation and relapse implies a hit and run mechanism inEBV-induced lymphomagenesis and brings out a speculation that a proportion of EBv-negative cHD could represent loss of EBV in the tumour prior to clinical presentation.

26 citations

Journal ArticleDOI
TL;DR: The feasibility of preserving the larynx at least in younger individuals and when good nursing care is available is stressed, and the choice of the various surgical procedures is discussed and the cure rates analysed.
Abstract: A study of 78 cases of base of the tongue cancer treated surgically for control of disease at the primary site is presented. Seventy-four of these cases were radiation failures, surgery being resorted to as a salvage procedure. The choice of the various surgical procedures is discussed and the cure rates analysed. Thirty-five cases required a total glossectomy, of which twenty-six did not have removal of the larynx. The feasibility of preserving the larynx at least in younger individuals and when good nursing care is available is stressed.

26 citations


Authors

Showing all 3213 results

NameH-indexPapersCitations
Al B. Benson11357848364
Keitaro Matsuo9781837349
Ashish K. Jha8750330020
Noopur Raje8250627878
Muthupandian Ashokkumar7651120771
Snehal G. Patel7336716905
Rainu Kaushal5823216794
Ajit S. Puri543699948
Jasbir S. Arora5135115696
Sudeep Sarkar4827310087
Ian T. Magrath471078084
Pankaj Chaturvedi4532515871
Pradeep Kumar Gupta444167181
Shiv K. Gupta431508911
Kikkeri N. Naresh432456264
Network Information
Related Institutions (5)
All India Institute of Medical Sciences
40.1K papers, 640.4K citations

91% related

The Royal Marsden NHS Foundation Trust
13.4K papers, 668.8K citations

87% related

Memorial Sloan Kettering Cancer Center
65.3K papers, 4.4M citations

85% related

University of Texas MD Anderson Cancer Center
92.5K papers, 4.7M citations

85% related

Peter MacCallum Cancer Centre
9.8K papers, 458.8K citations

84% related

Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20235
202232
2021223
2020244
2019206
2018239