Institution
Tata Memorial Hospital
Healthcare•Mumbai, India•
About: Tata Memorial Hospital is a healthcare organization based out in Mumbai, India. It is known for research contribution in the topics: Cancer & Breast cancer. The organization has 3187 authors who have published 4636 publications receiving 109143 citations.
Topics: Cancer, Breast cancer, Population, Radiation therapy, Carcinoma
Papers published on a yearly basis
Papers
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Memorial Sloan Kettering Cancer Center1, University of California, Davis2, Tel Aviv Sourasky Medical Center3, Toronto General Hospital4, Harvard University5, Japanese Foundation for Cancer Research6, University of Virginia7, University of São Paulo8, Tata Memorial Hospital9, University of Pittsburgh10, University of Hong Kong11
TL;DR: This international collaborative report examines a large cohort of patients accumulated from multiple institutions with the aim of identifying patient‐related and tumor‐related predictors of postoperative morbidity and mortality and set a benchmark for future studies.
Abstract: Background.
Advances in imaging, surgical technique, and perioperative care have made craniofacial resection (CFR) an effective and safe option for treating malignant tumors involving the skull base. The procedure does, however, have complications. Because of the relative rarity of these tumors, most existing data on postoperative complications come from individual reports of relatively small series of patients. This international collaborative report examines a large cohort of patients accumulated from multiple institutions with the aim of identifying patient-related and tumor-related predictors of postoperative morbidity and mortality and set a benchmark for future studies.
Methods.
One thousand one hundred ninety-three patients from 17 institutions were analyzed for postoperative mortality and complications. Postoperative complications were classified into systemic, wound, central nervous system (CNS), and orbit. Statistical analyses were carried out in relation to patient characteristics, extent of disease, prior radiation treatment, and type of reconstruction to determine factors that predicted mortality or complications.
Results.
Postoperative mortality occurred in 56 patients (4.7%). The presence of medical comorbidity was the only independent predictor of mortality. Postoperative complications occurred in 433 patients (36.3%). Wound complications occurred in 237 (19.8%), CNS-related complications in 193 (16.2%), orbital complications in 20 (1.7%), and systemic complications in 57 (4.8%) patients. Medical comorbidity, prior radiation therapy, and the extent of intracranial tumour involvement were independent predictors of postoperative complications.
Conclusions.
CFR is a safe surgical treatment for malignant tumors of the skull base, with an overall mortality of 4.7% and complication rate of 36.3%. The impact of medical comorbidity and intracranial tumor extent should be carefully considered when planning therapy for patients whose tumors are amenable to CFR. © 2005 Wiley Periodicals, Inc. Head Neck27: XXX–XXX, 2005
268 citations
TL;DR: This report summarizes 10 yr of experience with 18 F for bone scanning and finds that 80% of the cases were diagnosed correctly both by roentgenography and scanning, and where these two procedures disagreed, the scan was correct three times as often as the X ray.
267 citations
TL;DR: An attempt has been made to collate the information available on mechanisms of action of 4NQO, studies carried out for the development of biomarkers and chemopreventives agents using 4NZO animal models, which suggest that similar histological as well as molecular changes are observed in the human system.
263 citations
University College London1, Oregon Health & Science University2, Harvard University3, Lund University4, Vita-Salute San Raffaele University5, University of Manchester6, University of British Columbia7, Monash University8, The Royal Marsden NHS Foundation Trust9, Columbia University10, University of Texas MD Anderson Cancer Center11, University of California, Davis12, University of Bologna13, University of California, San Francisco14, Institut Gustave Roussy15, Duke University16, University of Cologne17, Medical University of Vienna18, University of Oslo19, Fred Hutchinson Cancer Research Center20, University of Washington21, Peter MacCallum Cancer Centre22, University of Melbourne23, Northwestern University24, Memorial Sloan Kettering Cancer Center25, Cornell University26, American University of Beirut27, Tel Aviv University28, National and Kapodistrian University of Athens29, Tata Memorial Hospital30, Icahn School of Medicine at Mount Sinai31, Ghent University32, Queen's University Belfast33, Belfast City Hospital34, The Chinese University of Hong Kong35, University of California, Los Angeles36, University of Bern37, University of Minnesota38, Université de Montréal39, Tulane University40, Prostate Cancer Foundation41, University of Hamburg42, Toho University43, Université catholique de Louvain44, Radboud University Nijmegen45, University of St. Gallen46
TL;DR: These voting results from a panel of prostate cancer experts can help clinicians and patients navigate controversial areas of advanced prostate management for which high-level evidence is sparse and provide a practical guide to help clinicians discuss therapeutic options with patients.
255 citations
TL;DR: IMRT significantly reduces the incidence and severity of xerostomia compared to 3D-CRT in curative-intent irradiation of head-neck squamous cell carcinoma of HNSCC.
240 citations
Authors
Showing all 3213 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Al B. Benson | 113 | 578 | 48364 |
| Keitaro Matsuo | 97 | 818 | 37349 |
| Ashish K. Jha | 87 | 503 | 30020 |
| Noopur Raje | 82 | 506 | 27878 |
| Muthupandian Ashokkumar | 76 | 511 | 20771 |
| Snehal G. Patel | 73 | 367 | 16905 |
| Rainu Kaushal | 58 | 232 | 16794 |
| Ajit S. Puri | 54 | 369 | 9948 |
| Jasbir S. Arora | 51 | 351 | 15696 |
| Sudeep Sarkar | 48 | 273 | 10087 |
| Ian T. Magrath | 47 | 107 | 8084 |
| Pankaj Chaturvedi | 45 | 325 | 15871 |
| Pradeep Kumar Gupta | 44 | 416 | 7181 |
| Shiv K. Gupta | 43 | 150 | 8911 |
| Kikkeri N. Naresh | 43 | 245 | 6264 |