Institution
Technical University of Berlin
Education•Berlin, Germany•
About: Technical University of Berlin is a education organization based out in Berlin, Germany. It is known for research contribution in the topics: Quantum dot & Laser. The organization has 27292 authors who have published 59342 publications receiving 1414623 citations. The organization is also known as: Technische Universität Berlin & TU Berlin.
Topics: Quantum dot, Laser, Catalysis, Population, Raman spectroscopy
Papers published on a yearly basis
Papers
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TL;DR: The growing understanding of the dual point of view is emphasized, which has brought considerable progress to the column generation theory and practice, and is an ever recurring concept in "selected topics."
Abstract: Dantzig-Wolfe decomposition and column generation, devised for linear programs, is a success story in large-scale integer programming. We outline and relate the approaches, and survey mainly recent contributions, not yet found in textbooks. We emphasize the growing understanding of the dual point of view, which has brought considerable progress to the column generation theory and practice. It stimulated careful initializations, sophisticated solution techniques for the restricted master problem and subproblem, as well as better overall performance. Thus, the dual perspective is an ever recurring concept in our "selected topics."
916 citations
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TL;DR: In terms of monitoring studies carried out in Berlin between 1996 and 2000, PhACs such as clofibric acid, diclofenac, ibuprofen, propyphenazone, primidone and carbamazepine were detected at individual concentrations up to the mu/I-level in influent and effluent samples from STPs and in all surface water samples collected downstream from the STPs.
898 citations
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TL;DR: Between 7 and 100 K the polarization decay has two distinct components resulting in a non-Lorentzian line shape with a lifetime-limited zero-phonon line and a broadband from elastic exciton-acoustic phonon interactions.
Abstract: We measure a dephasing time of several hundred picoseconds at low temperature in the ground-state transition of strongly confined InGaAs quantum dots, using a highly sensitive four-wave mixing technique. Between 7 and 100 K the polarization decay has two distinct components resulting in a non-Lorentzian line shape with a lifetime-limited zero-phonon line and a broadband from elastic exciton-acoustic phonon interactions.
896 citations
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TL;DR: This report is the first complete description of the biosynthesis pathway of a complex cyanobacterial metabolite and represents an integrated polyketide-peptide biosynthetic pathway with a number of unusual structural and enzyme features.
894 citations
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TL;DR: The characterized library of promoters is used to assess the impact of phosphoenolpyruvate carboxylase levels on growth yield and deoxy-xylulose-P synthase Levels on lycopene production and is illustrated as being generalizable to eukaryotic organisms and thus constitutes an integral platform for functional genomics, synthetic biology, and metabolic engineering endeavors.
Abstract: Gene function is typically evaluated by sampling the continuum of gene expression at only a few discrete points corresponding to gene knockout or overexpression. We argue that this characterization is incomplete and present a library of engineered promoters of varying strengths obtained through mutagenesis of a constitutive promoter. A multifaceted characterization of the library, especially at the single-cell level to ensure homogeneity, permitted quantitative assessment correlating the effect of gene expression levels to improved growth and product formation phenotypes in Escherichia coli. Integration of these promoters into the chromosome can allow for a quantitative accurate assessment of genetic control. To this end, we used the characterized library of promoters to assess the impact of phosphoenolpyruvate carboxylase levels on growth yield and deoxy-xylulose-P synthase levels on lycopene production. The multifaceted characterization of promoter strength enabled identification of optimal expression levels for ppc and dxs, which maximized the desired phenotype. Additionally, in a strain preengineered to produce lycopene, the response to deoxy-xylulose-P synthase levels was linear at all levels tested, indicative of a rate-limiting step, unlike the parental strain, which exhibited an optimum expression level, illustrating that optimal gene expression levels are variable and dependent on the genetic background of the strain. This promoter library concept is illustrated as being generalizable to eukaryotic organisms (Saccharomyces cerevisiae) and thus constitutes an integral platform for functional genomics, synthetic biology, and metabolic engineering endeavors.
892 citations
Authors
Showing all 27602 results
Name | H-index | Papers | Citations |
---|---|---|---|
Markus Antonietti | 176 | 1068 | 127235 |
Jian Li | 133 | 2863 | 87131 |
Klaus-Robert Müller | 129 | 764 | 79391 |
Michael Wagner | 124 | 351 | 54251 |
Shi Xue Dou | 122 | 2028 | 74031 |
Xinchen Wang | 120 | 349 | 65072 |
Michael S. Feld | 119 | 552 | 51968 |
Jian Liu | 117 | 2090 | 73156 |
Ary A. Hoffmann | 113 | 907 | 55354 |
Stefan Grimme | 113 | 680 | 105087 |
David M. Karl | 112 | 461 | 48702 |
Lester Packer | 112 | 751 | 63116 |
Andreas Heinz | 108 | 1078 | 45002 |
Horst Weller | 105 | 451 | 44273 |
G. Hughes | 103 | 957 | 46632 |