Institution
Technion – Israel Institute of Technology
Education•Haifa, Israel•
About: Technion – Israel Institute of Technology is a education organization based out in Haifa, Israel. It is known for research contribution in the topics: Population & Nonlinear system. The organization has 31714 authors who have published 79377 publications receiving 2603976 citations. The organization is also known as: Technion Israel Institute of Technology & Ṭekhniyon, Makhon ṭekhnologi le-Yiśraʼel.
Papers published on a yearly basis
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University College London1, University of Brescia2, Karolinska University Hospital3, University of Antioquia4, National Institute for Health Research5, John Radcliffe Hospital6, University of Liège7, Technion – Israel Institute of Technology8, North Sichuan Medical College9, Tehran University of Medical Sciences10, University Medical Center Freiburg11, Leiden University Medical Center12, National Institutes of Health13
TL;DR: It is concluded that mutations in LRBA cause an immune deficiency characterized by defects in B cell activation and autophagy and by susceptibility to apoptosis, all of which are associated with a clinical phenotype of hypogammaglobulinemia and autoimmunity.
Abstract: Most autosomal genetic causes of childhood-onset hypogammaglobulinemia are currently not well understood. Most affected individuals are simplex cases, but both autosomal-dominant and autosomal-recessive inheritance have been described. We performed genetic linkage analysis in consanguineous families affected by hypogammaglobulinemia. Four consanguineous families with childhood-onset humoral immune deficiency and features of autoimmunity shared genotype evidence for a linkage interval on chromosome 4q. Sequencing of positional candidate genes revealed that in each family, affected individuals had a distinct homozygous mutation in LRBA (lipopolysaccharide responsive beige-like anchor protein). All LRBA mutations segregated with the disease because homozygous individuals showed hypogammaglobulinemia and autoimmunity, whereas heterozygous individuals were healthy. These mutations were absent in healthy controls. Individuals with homozygous LRBA mutations had no LRBA, had disturbed B cell development, defective in vitro B cell activation, plasmablast formation, and immunoglobulin secretion, and had low proliferative responses. We conclude that mutations in LRBA cause an immune deficiency characterized by defects in B cell activation and autophagy and by susceptibility to apoptosis, all of which are associated with a clinical phenotype of hypogammaglobulinemia and autoimmunity.
425 citations
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TL;DR: In this paper, a new proof of the Kochen-Specker theorem using 33 rays instead of 117 in the original proof was presented, where the number of dimensions is increased from 3 to 4 and only 24 rays are needed.
Abstract: A new proof of the Kochen-Specker theorem uses 33 rays, instead of 117 in the original proof. If the number of dimensions is increased from 3 to 4, only 24 rays are needed.
425 citations
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17 Jun 2006TL;DR: This work addresses the image denoising problem, where zeromean white and homogeneous Gaussian additive noise should be removed from a given image, by defining a global image prior that forces sparsity over patches in every location in the image.
Abstract: We address the image denoising problem, where zeromean white and homogeneous Gaussian additive noise should be removed from a given image. The approach taken is based on sparse and redundant representations over a trained dictionary. The proposed algorithm denoises the image, while simultaneously trainining a dictionary on its (corrupted) content using the K-SVD algorithm. As the dictionary training algorithm is limited in handling small image patches, we extend its deployment to arbitrary image sizes by defining a global image prior that forces sparsity over patches in every location in the image. We show how such Bayesian treatment leads to a simple and effective denoising algorithm, with state-of-the-art performance, equivalent and sometimes surpassing recently published leading alternative denoising methods.
425 citations
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TL;DR: In this paper, the entanglement between the pairs of particles inside and outside a black hole has been studied, with tantalizing insights into the field of black hole thermodynamics.
Abstract: Hawking radiation is observed emanating from an analogue black hole, with measurements of the entanglement between the pairs of particles inside and outside the hole offering tantalizing insights into the field of black hole thermodynamics.
424 citations
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TL;DR: A concise, although admittedly nonexhaustive, didactic review of some of the main concepts and approaches related to the use of nanoparticles (NPs) in flexible sensors, mainly those established via electrical transduction approaches.
Abstract: Flexible sensors can be envisioned as promising components for smart sensing applications, including consumer electronics, robotics, prosthetics, health care, safety equipment, environmental monitoring, homeland security and space flight. The current review presents a concise, although admittedly nonexhaustive, didactic review of some of the main concepts and approaches related to the use of nanoparticles (NPs) in flexible sensors. The review attempts to pull together different views and terminologies used in the NP-based sensors, mainly those established via electrical transduction approaches, including, but, not confined to: (i) strain-gauges, (ii) flexible multiparametric sensors, and (iii) sensors that are unaffected by mechanical deformation. For each category, the review presents and discusses the common fabrication approaches and state-of-the-art results. The advantages, weak points, and possible routes for future research, highlighting the challenges for NP-based flexible sensors, are presented an...
424 citations
Authors
Showing all 31937 results
Name | H-index | Papers | Citations |
---|---|---|---|
Robert Langer | 281 | 2324 | 326306 |
Nicholas G. Martin | 192 | 1770 | 161952 |
Tobin J. Marks | 159 | 1621 | 111604 |
Grant W. Montgomery | 157 | 926 | 108118 |
David Eisenberg | 156 | 697 | 112460 |
David J. Mooney | 156 | 695 | 94172 |
Dirk Inzé | 149 | 647 | 74468 |
Jerrold M. Olefsky | 143 | 595 | 77356 |
Joseph J.Y. Sung | 142 | 1240 | 92035 |
Deborah Estrin | 135 | 562 | 106177 |
Bruce Yabsley | 133 | 1191 | 84889 |
Jerry W. Shay | 133 | 639 | 74774 |
Richard N. Bergman | 130 | 477 | 91718 |
Shlomit Tarem | 129 | 1306 | 86919 |
Allen Mincer | 129 | 1040 | 80059 |