Institution
Technion – Israel Institute of Technology
Education•Haifa, Israel•
About: Technion – Israel Institute of Technology is a education organization based out in Haifa, Israel. It is known for research contribution in the topics: Population & Upper and lower bounds. The organization has 31714 authors who have published 79377 publications receiving 2603976 citations. The organization is also known as: Technion Israel Institute of Technology & Ṭekhniyon, Makhon ṭekhnologi le-Yiśraʼel.
Topics: Population, Upper and lower bounds, Nonlinear system, Decoding methods, Large Hadron Collider
Papers published on a yearly basis
Papers
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TL;DR: The clonal derivation of two human ES cell lines, H9.1 and H.2, demonstrates the pluripotency of single human ES cells, the maintenance of pluripOTency during an extended period of culture, and the long-term self-renewing properties of cultured human ES Cells.
1,680 citations
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TL;DR: There is now solid genetic support for the hypothesis that mycoplasmas have evolved as a branch of gram-positive bacteria by a process of reductive evolution and developed various genetic systems providing a highly plastic set of variable surface proteins to evade the host immune system.
Abstract: The recent sequencing of the entire genomes of Mycoplasma genitalium and M. pneumoniae has attracted considerable attention to the molecular biology of mycoplasmas, the smallest self-replicating organisms. It appears that we are now much closer to the goal of defining, in molecular terms, the entire machinery of a self-replicating cell. Comparative genomics based on comparison of the genomic makeup of mycoplasmal genomes with those of other bacteria, has opened new ways of looking at the evolutionary history of the mycoplasmas. There is now solid genetic support for the hypothesis that mycoplasmas have evolved as a branch of gram-positive bacteria by a process of reductive evolution. During this process, the mycoplasmas lost considerable portions of their ancestors’ chromosomes but retained the genes essential for life. Thus, the mycoplasmal genomes carry a high percentage of conserved genes, greatly facilitating gene annotation. The significant genome compaction that occurred in mycoplasmas was made possible by adopting a parasitic mode of life. The supply of nutrients from their hosts apparently enabled mycoplasmas to lose, during evolution, the genes for many assimilative processes. During their evolution and adaptation to a parasitic mode of life, the mycoplasmas have developed various genetic systems providing a highly plastic set of variable surface proteins to evade the host immune system. The uniqueness of the mycoplasmal systems is manifested by the presence of highly mutable modules combined with an ability to expand the antigenic repertoire by generating structural alternatives, all compressed into limited genomic sequences. In the absence of a cell wall and a periplasmic space, the majority of surface variable antigens in mycoplasmas are lipoproteins. Apart from providing specific antimycoplasmal defense, the host immune system is also involved in the development of pathogenic lesions and exacerbation of mycoplasma induced diseases. Mycoplasmas are able to stimulate as well as suppress lymphocytes in a nonspecific, polyclonal manner, both in vitro and in vivo. As well as to affecting various subsets of lymphocytes, mycoplasmas and mycoplasma-derived cell components modulate the activities of monocytes/macrophages and NK cells and trigger the production of a wide variety of up-regulating and down-regulating cytokines and chemokines. Mycoplasma-mediated secretion of proinflammatory cytokines, such as tumor necrosis factor alpha, interleukin-1 (IL-1), and IL-6, by macrophages and of up-regulating cytokines by mitogenically stimulated lymphocytes plays a major role in mycoplasma-induced immune system modulation and inflammatory responses.
1,679 citations
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TL;DR: The Robust Optimization methodology is applied to produce “robust” solutions of the above LPs which are in a sense immuned against uncertainty for the NETLIB problems.
Abstract: Optimal solutions of Linear Programming problems may become severely infeasible if the nominal data is slightly perturbed. We demonstrate this phenomenon by studying 90 LPs from the well-known NETLIB collection. We then apply the Robust Optimization methodology (Ben-Tal and Nemirovski [1–3]; El Ghaoui et al. [5, 6]) to produce “robust” solutions of the above LPs which are in a sense immuned against uncertainty. Surprisingly, for the NETLIB problems these robust solutions nearly lose nothing in optimality.
1,674 citations
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17 Aug 1997TL;DR: This work states that this attack is applicable only to public key cryptosystems such as RSA, and not to secret key algorithms such as the Data Encryption Standard (DES).
Abstract: In September 1996 Boneh, Demillo, and Lipton from Bellcore announced a new type of cryptanalytic attack which exploits computational errors to find cryptographic keys. Their attack is based on algebraic properties of modular arithmetic, and thus it is applicable only to public key cryptosystems such as RSA, and not to secret key algorithms such as the Data Encryption Standard (DES).
1,662 citations
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Mohammad H. Forouzanfar1, Lily Alexander1, H. Ross Anderson2, Victoria F Bachman1 +718 more•Institutions (295)
TL;DR: The Global Burden of Disease, Injuries, and Risk Factor study 2013 (GBD 2013) as mentioned in this paper provides a timely opportunity to update the comparative risk assessment with new data for exposure, relative risks, and evidence on the appropriate counterfactual risk distribution.
1,656 citations
Authors
Showing all 31937 results
Name | H-index | Papers | Citations |
---|---|---|---|
Robert Langer | 281 | 2324 | 326306 |
Nicholas G. Martin | 192 | 1770 | 161952 |
Tobin J. Marks | 159 | 1621 | 111604 |
Grant W. Montgomery | 157 | 926 | 108118 |
David Eisenberg | 156 | 697 | 112460 |
David J. Mooney | 156 | 695 | 94172 |
Dirk Inzé | 149 | 647 | 74468 |
Jerrold M. Olefsky | 143 | 595 | 77356 |
Joseph J.Y. Sung | 142 | 1240 | 92035 |
Deborah Estrin | 135 | 562 | 106177 |
Bruce Yabsley | 133 | 1191 | 84889 |
Jerry W. Shay | 133 | 639 | 74774 |
Richard N. Bergman | 130 | 477 | 91718 |
Shlomit Tarem | 129 | 1306 | 86919 |
Allen Mincer | 129 | 1040 | 80059 |