scispace - formally typeset
Search or ask a question
Institution

Technion – Israel Institute of Technology

EducationHaifa, Israel
About: Technion – Israel Institute of Technology is a education organization based out in Haifa, Israel. It is known for research contribution in the topics: Population & Upper and lower bounds. The organization has 31714 authors who have published 79377 publications receiving 2603976 citations. The organization is also known as: Technion Israel Institute of Technology & Ṭekhniyon, Makhon ṭekhnologi le-Yiśraʼel.


Papers
More filters
Journal ArticleDOI
01 Sep 2016-Nature
TL;DR: It is demonstrated that a dynamical encircling of an exceptional point is analogous to the scattering through a two-mode waveguide with suitably designed boundaries and losses, and mode transitions are induced that transform this device into a robust and asymmetric switch between different waveguide modes.
Abstract: Physical systems with loss or gain have resonant modes that decay or grow exponentially with time. Whenever two such modes coalesce both in their resonant frequency and their rate of decay or growth, an 'exceptional point' occurs, giving rise to fascinating phenomena that defy our physical intuition. Particularly intriguing behaviour is predicted to appear when an exceptional point is encircled sufficiently slowly, such as a state-flip or the accumulation of a geometric phase. The topological structure of exceptional points has been experimentally explored, but a full dynamical encircling of such a point and the associated breakdown of adiabaticity have remained out of reach of measurement. Here we demonstrate that a dynamical encircling of an exceptional point is analogous to the scattering through a two-mode waveguide with suitably designed boundaries and losses. We present experimental results from a corresponding waveguide structure that steers incoming waves around an exceptional point during the transmission process. In this way, mode transitions are induced that transform this device into a robust and asymmetric switch between different waveguide modes. This work will enable the exploration of exceptional point physics in system control and state transfer schemes at the crossroads between fundamental research and practical applications.

776 citations

Journal ArticleDOI
TL;DR: This work shows that disruption of Xrn1 activity preferentially affects both the synthesis and decay of a distinct subpopulation of mRNAs, and proposes to name the most affected genes “Xrn1 synthegradon.”
Abstract: The 5’ to 3’ exoribonuclease Xrn1 is a large protein involved in cytoplasmatic mRNA degradation as a critical component of the major decaysome. Its deletion in the yeast Saccharomyces cerevisiae is not lethal, but it has multiple physiological effects. In a previous study, our group showed that deletion of all tested components of the yeast major decaysome, including XRN1, results in a decrease in the synthetic rate and an increase in half-life of most mRNAs in a compensatory manner. Furthermore, the same study showed that the all tested decaysome components are also nuclear proteins that bind to the 5’ region of a number of genes. In the present work, we show that disruption of Xrn1 activity preferentially affects both the synthesis and decay of a distinct subpopulation of mRNAs. The most affected mRNAs are the transcripts of the highly transcribed genes, mainly those encoding ribosome biogenesis and translation factors. Previously, we proposed that synthegradases play a key role in regulating both mRNA synthesis and degradation. Evidently, Xrn1 functions as a synthegradase, whose selectivity might help coordinating the expression of the protein synthetic machinery. We propose to name the most affected genes “Xrn1 synthegradon”.

775 citations

Journal ArticleDOI
TL;DR: The profile of gene expression observed in H1 cells was similar to that of two other human ES cell lines tested, indicating that the observed differences between human and mouse ES cells were species-specific rather than arising from differences in culture conditions.

774 citations

Journal ArticleDOI
TL;DR: This paper describes how to choose the parameters of the multi-coset sampling so that a unique multiband signal matches the given samples, and develops a theoretical lower bound on the average sampling rate required for blind signal reconstruction, which is twice the minimal rate of known-spectrum recovery.
Abstract: We address the problem of reconstructing a multiband signal from its sub-Nyquist pointwise samples, when the band locations are unknown. Our approach assumes an existing multi-coset sampling. To date, recovery methods for this sampling strategy ensure perfect reconstruction either when the band locations are known, or under strict restrictions on the possible spectral supports. In this paper, only the number of bands and their widths are assumed without any other limitations on the support. We describe how to choose the parameters of the multi-coset sampling so that a unique multiband signal matches the given samples. To recover the signal, the continuous reconstruction is replaced by a single finite-dimensional problem without the need for discretization. The resulting problem is studied within the framework of compressed sensing, and thus can be solved efficiently using known tractable algorithms from this emerging area. We also develop a theoretical lower bound on the average sampling rate required for blind signal reconstruction, which is twice the minimal rate of known-spectrum recovery. Our method ensures perfect reconstruction for a wide class of signals sampled at the minimal rate, and provides a first systematic study of compressed sensing in a truly analog setting. Numerical experiments are presented demonstrating blind sampling and reconstruction with minimal sampling rate.

769 citations

Journal ArticleDOI
TL;DR: In this paper, the impact of drops impinging one by one on a solid surface is studied experimentally and theoretically, and it is shown that the splashing threshold corresponds to the onset of a velocity discontinuity propagating over the liquid layer on the wall.
Abstract: The impact of drops impinging one by one on a solid surface is studied experimentally and theoretically. The impact process is observed by means of a charge-coupled-device camera, its pictures processed by computer. Low-velocity impact results in spreading and in propagation of capillary waves, whereas at higher velocities splashing (i.e. the emergence of a cloud of small secondary droplets, absent in the former case) sets in. Capillary waves are studied in some detail in separate experiments. The dynamics of the extension of liquid lamellae produced by an impact in the case of splashing is recorded. The secondary-droplet size distributions and the total volume of these droplets are measured, and the splashing threshold is found as a function of the impact parameters.The pattern of the capillary waves is predicted to be self-similar. The calculated wave profile agrees well with the experimental data. It is shown theoretically that the splashing threshold corresponds to the onset of a velocity discontinuity propagating over the liquid layer on the wall. This discontinuity shows several aspects of a shock. In an incompressible liquid such a discontinuity can only exist in the presence of a sink at its front. The latter results in the emergence of a circular crown-like sheet virtually normal to the wall and propagating with the discontinuity. It is predicted theoretically and recorded in the experiment. The crown is unstable owing to the formation of cusps at the free rim at its top edge, which results in the splashing effect. The onset velocity of splashing and the rate of propagation of the kinematic discontinuity are calculated and the theoretical results agree fairly well with the experimental data. The structure of the discontinuity is shown to match the outer solution.

767 citations


Authors

Showing all 31937 results

NameH-indexPapersCitations
Robert Langer2812324326306
Nicholas G. Martin1921770161952
Tobin J. Marks1591621111604
Grant W. Montgomery157926108118
David Eisenberg156697112460
David J. Mooney15669594172
Dirk Inzé14964774468
Jerrold M. Olefsky14359577356
Joseph J.Y. Sung142124092035
Deborah Estrin135562106177
Bruce Yabsley133119184889
Jerry W. Shay13363974774
Richard N. Bergman13047791718
Shlomit Tarem129130686919
Allen Mincer129104080059
Network Information
Related Institutions (5)
Imperial College London
209.1K papers, 9.3M citations

93% related

Massachusetts Institute of Technology
268K papers, 18.2M citations

92% related

University of Illinois at Urbana–Champaign
225.1K papers, 10.1M citations

92% related

Stanford University
320.3K papers, 21.8M citations

92% related

University of Toronto
294.9K papers, 13.5M citations

92% related

Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023147
2022390
20213,397
20203,526
20193,273
20183,131