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Institution

Tehran University of Medical Sciences

EducationTehran, Iran
About: Tehran University of Medical Sciences is a education organization based out in Tehran, Iran. It is known for research contribution in the topics: Population & Cancer. The organization has 35661 authors who have published 57234 publications receiving 878523 citations. The organization is also known as: TUMS.


Papers
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Journal ArticleDOI
TL;DR: Over the past generation, the global burden of Parkinson's disease has more than doubled as a result of increasing numbers of older people, with potential contributions from longer disease duration and environmental factors.
Abstract: Summary Background Neurological disorders are now the leading source of disability globally, and ageing is increasing the burden of neurodegenerative disorders, including Parkinson's disease. We aimed to determine the global burden of Parkinson's disease between 1990 and 2016 to identify trends and to enable appropriate public health, medical, and scientific responses. Methods Through a systematic analysis of epidemiological studies, we estimated global, regional, and country-specific prevalence and years of life lived with disability for Parkinson's disease from 1990 to 2016. We estimated the proportion of mild, moderate, and severe Parkinson's disease on the basis of studies that used the Hoehn and Yahr scale and assigned disability weights to each level. We jointly modelled prevalence and excess mortality risk in a natural history model to derive estimates of deaths due to Parkinson's disease. Death counts were multiplied by values from the Global Burden of Disease study's standard life expectancy to compute years of life lost. Disability-adjusted life-years (DALYs) were computed as the sum of years lived with disability and years of life lost. We also analysed results based on the Socio-demographic Index, a compound measure of income per capita, education, and fertility. Findings In 2016, 6·1 million (95% uncertainty interval [UI] 5·0–7·3) individuals had Parkinson's disease globally, compared with 2·5 million (2·0–3·0) in 1990. This increase was not solely due to increasing numbers of older people, because age-standardised prevalence rates increased by 21·7% (95% UI 18·1–25·3) over the same period (compared with an increase of 74·3%, 95% UI 69·2–79·6, for crude prevalence rates). Parkinson's disease caused 3·2 million (95% UI 2·6–4·0) DALYs and 211 296 deaths (95% UI 167 771–265 160) in 2016. The male-to-female ratios of age-standardised prevalence rates were similar in 2016 (1·40, 95% UI 1·36–1·43) and 1990 (1·37, 1·34–1·40). From 1990 to 2016, age-standardised prevalence, DALY rates, and death rates increased for all global burden of disease regions except for southern Latin America, eastern Europe, and Oceania. In addition, age-standardised DALY rates generally increased across the Socio-demographic Index. Interpretation Over the past generation, the global burden of Parkinson's disease has more than doubled as a result of increasing numbers of older people, with potential contributions from longer disease duration and environmental factors. Demographic and potentially other factors are poised to increase the future burden of Parkinson's disease substantially. Funding Bill & Melinda Gates Foundation.

1,388 citations

Journal ArticleDOI
TL;DR: Global rates of change suggest that only 16 countries will achieve the MDG 5 target by 2015, with evidence of continued acceleration in the MMR, and MMR was highest in the oldest age groups in both 1990 and 2013.

1,383 citations

Journal ArticleDOI
26 Jul 2016-eLife
TL;DR: The height differential between the tallest and shortest populations was 19-20 cm a century ago, and has remained the same for women and increased for men a century later despite substantial changes in the ranking of countries.
Abstract: Being taller is associated with enhanced longevity, and higher education and earnings. We reanalysed 1472 population-based studies, with measurement of height on more than 18.6 million participants to estimate mean height for people born between 1896 and 1996 in 200 countries. The largest gain in adult height over the past century has occurred in South Korean women and Iranian men, who became 20.2 cm (95% credible interval 17.5–22.7) and 16.5 cm (13.3–19.7) taller, respectively. In contrast, there was little change in adult height in some sub-Saharan African countries and in South Asia over the century of analysis. The tallest people over these 100 years are men born in the Netherlands in the last quarter of 20th century, whose average heights surpassed 182.5 cm, and the shortest were women born in Guatemala in 1896 (140.3 cm; 135.8–144.8). The height differential between the tallest and shortest populations was 19-20 cm a century ago, and has remained the same for women and increased for men a century later despite substantial changes in the ranking of countries.

1,348 citations

Book
01 Jan 2005
TL;DR: State-of-the-art coverage of anesthetic drugs, guidelines for anesthetic practice and patient safety, new techniques, step-by-step instructions for patient management, the unique needs of pediatric patients, and much more - all highlighted by more than 1,500 full-color illustrations for enhanced visual clarity.
Abstract: Covering everything from historical and international perspectives to basic science and current clinical practice, Miller's Anesthesia, 9th Edition, remains the preeminent reference in the field. Dr. Michael Gropper leads a team of global experts who bring you the most up-to-date information available on the technical, scientific, and clinical issues you face each day - whether you're preparing for the boards, studying for recertification, or managing a challenging patient care situation in your practice. Contains fully revised and updated content throughout, including numerous new videos online. Includes four new chapters: Clinical Care in Extreme Environments: High Pressure, Immersion, and Hypo- and Hyperthermia; Immediate and Long-Term Complications; Clinical Research; and Interpreting the Medical Literature. Addresses timely topics such as neurotoxicity, palliation, and sleep/wake disorders. Streamlines several topics into single chapters with fresh perspectives from new authors, making the material more readable and actionable. Features the knowledge and expertise of former lead editor Dr. Ronald Miller, as well as new editor Dr. Kate Leslie of the University of Melbourne and Royal Melbourne Hospital. Provides state-of-the-art coverage of anesthetic drugs, guidelines for anesthetic practice and patient safety, new techniques, step-by-step instructions for patient management, the unique needs of pediatric patients, and much more - all highlighted by more than 1,500 full-color illustrations for enhanced visual clarity.

1,348 citations

Journal ArticleDOI
TL;DR: Protein Nanoparticle Interactions: Opportunities and Challenges
Abstract: Protein Nanoparticle Interactions: Opportunities and Challenges Morteza Mahmoudi,* Iseult Lynch, Mohammad Reza Ejtehadi, Marco P. Monopoli, Francesca Baldelli Bombelli, and Sophie Laurent National Cell Bank, Pasteur Institute of Iran, Tehran, Iran Nanotechnology Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran School of Chemistry and Chemical Biology & Conway Institute for Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland Department of Physics, Sharif University of Technology, Tehran, Iran School of Pharmacy, UEA, Norwich Research Park, Norwich,U.K. Department of General, Organic, and Biomedical Chemistry, NMR and Molecular Imaging Laboratory, University of Mons, Avenue Maistriau 19, B-7000 Mons, Belgium

1,214 citations


Authors

Showing all 35946 results

NameH-indexPapersCitations
Graeme J. Hankey137844143373
Paul D.P. Pharoah13079471338
Jerome Ritz12064447987
Reza Malekzadeh118900139272
Robert N. Weinreb117112459101
Javad Parvizi11196951075
Omid C. Farokhzad11032964226
Ali Mohammadi106114954596
Alexander R. Vaccaro102117939346
John R. Speakman9566734484
Philip J. Devereaux94443110428
Rafael Lozano94265126513
Mohammad Abdollahi90104535531
Ingmar Skoog8945828998
Morteza Mahmoudi8333426229
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023105
2022524
20216,041
20206,181
20195,322
20184,885