Institution
Tehran University of Medical Sciences
Education•Tehran, Iran•
About: Tehran University of Medical Sciences is a education organization based out in Tehran, Iran. It is known for research contribution in the topics: Population & Cancer. The organization has 35661 authors who have published 57234 publications receiving 878523 citations. The organization is also known as: TUMS.
Papers published on a yearly basis
Papers
More filters
TL;DR: Different aspects of chitinases and chi-lectins from bacteria, fungi, insects, plants and mammals are discussed.
172 citations
TL;DR: The different purposes, review designs, questions, synthesis methods and opportunities to combine quantitative and qualitative evidence to explore the complexity of complex interventions and health systems are clarified.
Abstract: Guideline developers are increasingly dealing with more difficult decisions concerning whether to recommend complex interventions in complex and highly variable health systems. There is greater recognition that both quantitative and qualitative evidence can be combined in a mixed-method synthesis and that this can be helpful in understanding how complexity impacts on interventions in specific contexts. This paper aims to clarify the different purposes, review designs, questions, synthesis methods and opportunities to combine quantitative and qualitative evidence to explore the complexity of complex interventions and health systems. Three case studies of guidelines developed by WHO, which incorporated quantitative and qualitative evidence, are used to illustrate possible uses of mixed-method reviews and evidence. Additional examples of methods that can be used or may have potential for use in a guideline process are outlined. Consideration is given to the opportunities for potential integration of quantitative and qualitative evidence at different stages of the review and guideline process. Encouragement is given to guideline commissioners and developers and review authors to consider including quantitative and qualitative evidence. Recommendations are made concerning the future development of methods to better address questions in systematic reviews and guidelines that adopt a complexity perspective.
171 citations
TL;DR: Simple, traditional microscopic measurements may be sufficient for the morphometric characterisation of fasciolids, even in areas where intermediate forms are present, as shown in the specimens from Gilan.
171 citations
Institute for Health Metrics and Evaluation1, University of Limoges2, University College Hospital, Ibadan3, Obafemi Awolowo University4, Tehran University of Medical Sciences5, Mayo Clinic6, Cleveland Clinic7, Iran University of Medical Sciences8, Essentia Health9, Georgia Regents University10, Babol University of Medical Sciences11, Karolinska Institutet12, University of Porto13, University of Washington14, Mazandaran University of Medical Sciences15, Federal University of Bahia16, University of Louisville17, A.T. Still University18, Kaiser Permanente19, University of North Carolina at Chapel Hill20, Hamdan bin Mohammed e-University21, University of Ibadan22, Shahid Beheshti University of Medical Sciences and Health Services23, University of Tartu24, Medical Research Council25, University of Cape Town26, KISA27, University of South Carolina28, Metropolitan University29, Brown University30, University of Manitoba31, University of Virginia32, National Institutes of Health33, Kyrgyz State Medical Academy34, King Saud University35, Carol Davila University of Medicine and Pharmacy36, Duy Tan University37, Maimonides Medical Center38, University of Bern39, University College London40, Imperial College London41, Public Health England42, West Virginia University43, Ain Shams University44, Adigrat University45, Hanoi Medical University46, Gomal University47, Harvard University48, Guy's and St Thomas' NHS Foundation Trust49, King's College London50
TL;DR: These global and national estimates demonstrate that CAVD and degenerative mitral valve disease are important causes of disease burden among older adults, with highest age-standardized DALY rates of CAVD estimated for high-income countries.
Abstract: Background: Nonrheumatic valvular diseases are common; however, no studies have estimated their global or national burden. As part of the Global Burden of Disease Study 2017, mortality, prevalence,...
171 citations
TL;DR: The modification of conventional toxicity assays and the consideration of the “cell vision” concept are crucial matters to obtain reliable, and reproducible nanotoxicology data and offer a suitable way to obtain a deep understanding on the cell-NP interactions.
Abstract: Until now, the results of nanotoxicology research have shown that the interactions between nanoparticles (NPs) and cells are remarkably complex. In order to get a deep understanding of the NP-cell interactions, scientists have focused on the physicochemical effects. However, there are still considerable debates about the regulation of nanomaterials and the reported results are usually in contradictions. Here, we are going to introduce the potential key reasons for these conflicts. In this case, modification of conventional in vitro toxicity assays, is one of the crucial ignored matter in nanotoxicological sciences. More specifically, the conventional methods neglect important factors such as the sedimentation of NPs and absorption of proteins and other essential biomolecules onto the surface of NPs. Another ignored matter in nanotoxicological sciences is the effect of cell “vision” (i.e., cell type). In order to show the effects of these ignored subjects, we probed the effect of superparamagnetic iron oxide NPs (SPIONs), with various surface chemistries, on various cell lines. We found thatthe modification of conventional toxicity assays and the consideration of the “cell vision” concept are crucial matters to obtain reliable, and reproducible nanotoxicology data. These new concepts offer a suitable way to obtain a deep understanding on the cell-NP interactions. In addition, by consideration of these ignored factors, the conflict of future toxicological reports would be significantly decreased.
171 citations
Authors
Showing all 35946 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Graeme J. Hankey | 137 | 844 | 143373 |
| Paul D.P. Pharoah | 130 | 794 | 71338 |
| Jerome Ritz | 120 | 644 | 47987 |
| Reza Malekzadeh | 118 | 900 | 139272 |
| Robert N. Weinreb | 117 | 1124 | 59101 |
| Javad Parvizi | 111 | 969 | 51075 |
| Omid C. Farokhzad | 110 | 329 | 64226 |
| Ali Mohammadi | 106 | 1149 | 54596 |
| Alexander R. Vaccaro | 102 | 1179 | 39346 |
| John R. Speakman | 95 | 667 | 34484 |
| Philip J. Devereaux | 94 | 443 | 110428 |
| Rafael Lozano | 94 | 265 | 126513 |
| Mohammad Abdollahi | 90 | 1045 | 35531 |
| Ingmar Skoog | 89 | 458 | 28998 |
| Morteza Mahmoudi | 83 | 334 | 26229 |