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Institution

Temple University

EducationPhiladelphia, Pennsylvania, United States
About: Temple University is a education organization based out in Philadelphia, Pennsylvania, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 32154 authors who have published 64375 publications receiving 2219828 citations.


Papers
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Journal ArticleDOI
TL;DR: In some cases the comparison of two models using ICs can be viewed as equivalent to a likelihood ratio test, with the different criteria representing different alpha levels and BIC being a more conservative test than AIC.
Abstract: Choosing a model with too few parameters can involve making unrealistically simple assumptions and lead to high bias, poor prediction, and missed opportunities for insight. Such models are not flexible enough to describe the sample or the population well. A model with too many parameters can fit the observed data very well, but be too closely tailored to it. Such models may generalize poorly. Penalizedlikelihood information criteria, such as Akaike’s Information Criterion (AIC), the Bayesian Information Criterion (BIC), the Consistent AIC, and the Adjusted BIC, are widely used for model selection. However, different criteria sometimes support different models, leading to uncertainty about which criterion is the most trustworthy. In some simple cases the comparison of two models using information criteria can be viewed as equivalent to a likelihood ratio test, with the different models representing different alpha levels (i.e., different emphases on sensitivity or specificity; Lin & Dayton 1997). This perspective may lead to insights about how to interpret the criteria in less simple situations. For example, AIC or BIC could be preferable, depending on sample size and on the relative importance one assigns to sensitivity versus specificity. Understanding the differences among the criteria may make it easier to compare their results and to use them to make informed decisions.

444 citations

Journal ArticleDOI
Aude Nicolas1, Kevin P. Kenna2, Alan E. Renton3, Alan E. Renton1  +432 moreInstitutions (78)
21 Mar 2018-Neuron
TL;DR: Interestingly, mutations predominantly in the N-terminal motor domain of KIF5A are causative for two neurodegenerative diseases: hereditary spastic paraplegia and Charcot-Marie-Tooth type 2.

444 citations

Journal ArticleDOI
TL;DR: It is found that Gαq stimulates YAP through a Trio-Rho/Rac signaling circuitry promoting actin polymerization, independently of phospholipase Cβ and the canonical Hippo pathway, thereby identifying YAP as a suitable therapeutic target in uveal melanoma, a GNAQ/GNA11-initiated human malignancy.

442 citations

Journal ArticleDOI
TL;DR: Sidelobe control of the transmit beamforming in tandem with waveform diversity enables communication links using the same pulse radar spectrum and it is shown that the communication process is inherently secure against intercept from directions other than the pre-assigned communication directions.
Abstract: We develop a new technique for a dual-function system with joint radar and communication platforms. Sidelobe control of the transmit beamforming in tandem with waveform diversity enables communication links using the same pulse radar spectrum. Multiple simultaneously transmitted orthogonal waveforms are used for embedding a sequence of LB bits during each radar pulse. Two weight vectors are designed to achieve two transmit spatial power distribution patterns, which have the same main radar beam, but differ in sidelobe levels towards the intended communication receivers. The receiver interpretation of the bit is based on its radiated beam. The proposed technique allows information delivery to single or multiple communication directions outside the mainlobe of the radar. It is shown that the communication process is inherently secure against intercept from directions other than the pre-assigned communication directions. The employed waveform diversity scheme supports a multiple-input multiple-output radar operation mode. The performance of the proposed technique is investigated in terms of the bit error rate.

442 citations

Journal ArticleDOI
TL;DR: The existence of efficient exciton-exciton annihilation, a four-body interaction, in Monolayer MoS2 is reported, a direct-gap two-dimensional semiconductor that exhibits strong electron-hole interactions, leading to the formation of stable excitons and trions.
Abstract: Monolayer MoS2 is a direct-gap two-dimensional semiconductor that exhibits strong electron–hole interactions, leading to the formation of stable excitons and trions. Here we report the existence of efficient exciton–exciton annihilation, a four-body interaction, in this material. Exciton–exciton annihilation was identified experimentally in ultrafast transient absorption measurements through the emergence of a decay channel varying quadratically with exciton density. The rate of exciton–exciton annihilation was determined to be (4.3 ± 1.1) × 10–2 cm2/s at room temperature.

442 citations


Authors

Showing all 32360 results

NameH-indexPapersCitations
Robert J. Lefkowitz214860147995
Rakesh K. Jain2001467177727
Virginia M.-Y. Lee194993148820
Yury Gogotsi171956144520
Timothy A. Springer167669122421
Ralph A. DeFronzo160759132993
James J. Collins15166989476
Robert J. Glynn14674888387
Edward G. Lakatta14685888637
Steven Williams144137586712
Peter Buchholz143118192101
David Goldstein1411301101955
Scott D. Solomon1371145103041
Donald B. Rubin132515262632
Jeffery D. Molkentin13148261594
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202366
2022335
20213,475
20203,281
20193,166
20183,019