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Institution

Temple University

EducationPhiladelphia, Pennsylvania, United States
About: Temple University is a education organization based out in Philadelphia, Pennsylvania, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 32154 authors who have published 64375 publications receiving 2219828 citations.


Papers
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Journal ArticleDOI
TL;DR: In this article, the authors identify the most critical strategic, tactical, and information-gathering activities influencing the launch success, and then use a retrospective methodology to gather managerial perceptions regarding launch activities pertaining to a recent new product launch, and the product performance in terms of profitability, market share, and relative sales.

355 citations

Journal ArticleDOI
TL;DR: Using mouse melanoma models, it is reported that CD8+ TILs enhance peroxisome proliferator-activated receptor (PPAR)-α signaling and catabolism of fatty acids (FAs) when simultaneously subjected to hypoglycemia and hypoxia.

354 citations

Journal ArticleDOI
TL;DR: The study of JCV and the elucidation of the underlying causes of PML are important and active areas of research that may lead to new insights into immune function and host antiviral defense, as well as to potential new therapies.
Abstract: Summary: Progressive multifocal leukoencephalopathy (PML) is a debilitating and frequently fatal central nervous system (CNS) demyelinating disease caused by JC virus (JCV), for which there is currently no effective treatment. Lytic infection of oligodendrocytes in the brain leads to their eventual destruction and progressive demyelination, resulting in multiple foci of lesions in the white matter of the brain. Before the mid-1980s, PML was a relatively rare disease, reported to occur primarily in those with underlying neoplastic conditions affecting immune function and, more rarely, in allograft recipients receiving immunosuppressive drugs. However, with the onset of the AIDS pandemic, the incidence of PML has increased dramatically. Approximately 3 to 5% of HIV-infected individuals will develop PML, which is classified as an AIDS-defining illness. In addition, the recent advent of humanized monoclonal antibody therapy for the treatment of autoimmune inflammatory diseases such as multiple sclerosis (MS) and Crohn's disease has also led to an increased risk of PML as a side effect of immunotherapy. Thus, the study of JCV and the elucidation of the underlying causes of PML are important and active areas of research that may lead to new insights into immune function and host antiviral defense, as well as to potential new therapies.

354 citations

Journal ArticleDOI
TL;DR: While the topics of business ethics and social responsibility education have received much attention in scholarly and pedagogical literature as discussed by the authors, the authors of this paper focus on the business ethics education.
Abstract: While the topics of business ethics and social responsibility education have received much attention in scholarly and pedagogical literature (although less in the pedagogical literature), the autho...

354 citations

Journal ArticleDOI
TL;DR: Risk of noncancer deaths now surpasses that of cancer deaths, particularly for young patients in the year after diagnosis, particularly if they are diagnosed with testicular cancer.

354 citations


Authors

Showing all 32360 results

NameH-indexPapersCitations
Robert J. Lefkowitz214860147995
Rakesh K. Jain2001467177727
Virginia M.-Y. Lee194993148820
Yury Gogotsi171956144520
Timothy A. Springer167669122421
Ralph A. DeFronzo160759132993
James J. Collins15166989476
Robert J. Glynn14674888387
Edward G. Lakatta14685888637
Steven Williams144137586712
Peter Buchholz143118192101
David Goldstein1411301101955
Scott D. Solomon1371145103041
Donald B. Rubin132515262632
Jeffery D. Molkentin13148261594
Network Information
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202366
2022335
20213,475
20203,281
20193,166
20183,019