Temple University

About: Temple University is a education organization based out in Philadelphia, Pennsylvania, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 32154 authors who have published 64375 publications receiving 2219828 citations.

Maximum Permissible Ambient Noise Levels for Audiometric Test Rooms.

Abstract: This Standard speci es maximum permissible ambient noise levels (MPANLs) allowed in an audiometric test room that produce negligible masking ( 2 dB) of test signals presented at reference equivalent threshold levels speci ed in ANSI S3.6-1996 American National Standard Speci cation of Audiometers. The MPANLs are speci ed from 125 to 8000 Hz in octave and one-third octave band intervals for two audiometric testing conditions (ears covered and ears not covered) and for three test frequency ranges (125 to 8000 Hz, 250 to 8000 Hz, and 500 to 8000 Hz). The Standard is intended for use by all persons testing hearing and for distributors, installers, designers, and manufacturers of audiometric test rooms. This standard is a revision of ANSI S3.1-1991 American National Standard Maximum Permissible Ambient Noise Levels for Audiometric Test Rooms. ANSI S3.1-1999 (Revision of ANSI S3.1-1991) Reaffirmed by ANSI October 15, 2003 Reaffirmed by ANSI October 28, 2008 Reaffir med by ANSI on June 24, 2007 Reaffir med by ANSI on June 24, 2007 This is a preview of \"ANSI/ASA S3.1-1999 (...\". Click here to purchase the full version from the ANSI store.

GADD45b and GADD45g are cdc2/cyclinB1 kinase inhibitors with a role in S and G2/M cell cycle checkpoints induced by genotoxic stress.

Abstract: Gadd45a (Gadd45), Gadd45b (MyD118), and Gadd45g (CR6) constitute a family of evolutionarily conserved, small, acidic, nuclear proteins, which have been implicated in terminal differentiation, growth suppression, and apoptosis. How Gadd45 proteins function in negative growth control is not fully understood. Recent evidence has implicated Gadd45a in inhibition of cdc2/cyclinB1 kinase and in G2/M cell cycle arrest. Yet, whether Gadd45b and/or Gadd45g function as inhibitors of cdc2/cyclinB1 kinase and/or play a role in G2/M cell cycle arrest has not been fully established. In this work, we show that Gadd45b and Gadd45g specifically interact with the Cdk1/CyclinB1 complex, but not with other Cdk/Cyclin complexes, in vitro and in vivo. Data also has been obtained that Gadd45b and Gadd45g, as well as GADD45a, interact with both Cdk1 and cyclinB1, resulting in inhibition of the kinase activity of the Cdk1/cyclinB1 complex. Inhibition of Cdk1/cyclinB1 kinase activity by Gadd45b and Gadd45a was found to involve disruption of the complex, whereas Gadd45g did not disrupt the complex. Moreover, using RKO lung carcinoma cell lines, which express antisense Gadd45 RNA, data has been obtained, which indicates that all three Gadd45 proteins are likely to cooperate in activation of S and G2/M checkpoints following exposure of cells to UV irradiation.

Excitons in conjugated oligomer aggregates, films, and crystals.

Abstract: Recent experimental and theoretical investigations of excitons in conjugated oligomer nanoaggregates, thin films, and crystals are reviewed. The review focuses on the technologically important unsubstituted oligo-phenylene vinylenes (OPVn) and oligo-thiophenes (OTn), which exhibit side-by-side herringbone crystal packing. Many of the salient photophysical properties displayed by OPVn and OTn solid phases, including the large Davydov splitting, the rich variety of peaks due to vibronic coupling in both absorption and emission, and the unusual behavior of the emission origin, are accounted for in a model including excitonic coupling between molecules, linear exciton-phonon coupling, and disorder.