Institution
Temple University
Education•Philadelphia, Pennsylvania, United States•
About: Temple University is a education organization based out in Philadelphia, Pennsylvania, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 32154 authors who have published 64375 publications receiving 2219828 citations.
Topics: Population, Poison control, Anxiety, Health care, Receptor
Papers published on a yearly basis
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3,163 citations
TL;DR: This review will discuss the biological processes and the structure and function of CCL2, one of the key chemokines that regulate migration and infiltration of monocytes/macrophages.
Abstract: Chemokines constitute a family of chemoattractant cytokines and are subdivided into four families on the basis of the number and spacing of the conserved cysteine residues in the N-terminus of the protein. Chemokines play a major role in selectively recruiting monocytes, neutrophils, and lymphocytes, as well as in inducing chemotaxis through the activation of G-protein-coupled receptors. Monocyte chemoattractant protein-1 (MCP-1/CCL2) is one of the key chemokines that regulate migration and infiltration of monocytes/macrophages. Both CCL2 and its receptor CCR2 have been demonstrated to be induced and involved in various diseases. Migration of monocytes from the blood stream across the vascular endothelium is required for routine immunological surveillance of tissues, as well as in response to inflammation. This review will discuss these biological processes and the structure and function of CCL2.
3,050 citations
TL;DR: Mental health affects progress towards the achievement of several Millennium Development Goals, such as promotion of gender equality and empowerment of women, reduction of child mortality, improvement of maternal health, and reversal of the spread of HIV/AIDS.
2,943 citations
TL;DR: This article proposes a framework for theory and research on risk-taking that is informed by developmental neuroscience, and finds that changes in the brain's cognitive control system - changes which improve individuals' capacity for self-regulation - occur across adolescence and young adulthood.
2,857 citations
2,819 citations
Authors
Showing all 32360 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Robert J. Lefkowitz | 214 | 860 | 147995 |
| Rakesh K. Jain | 200 | 1467 | 177727 |
| Virginia M.-Y. Lee | 194 | 993 | 148820 |
| Yury Gogotsi | 171 | 956 | 144520 |
| Timothy A. Springer | 167 | 669 | 122421 |
| Ralph A. DeFronzo | 160 | 759 | 132993 |
| James J. Collins | 151 | 669 | 89476 |
| Robert J. Glynn | 146 | 748 | 88387 |
| Edward G. Lakatta | 146 | 858 | 88637 |
| Steven Williams | 144 | 1375 | 86712 |
| Peter Buchholz | 143 | 1181 | 92101 |
| David Goldstein | 141 | 1301 | 101955 |
| Scott D. Solomon | 137 | 1145 | 103041 |
| Donald B. Rubin | 132 | 515 | 262632 |
| Jeffery D. Molkentin | 131 | 482 | 61594 |