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Showing papers by "Texas Christian University published in 2012"


Journal ArticleDOI
TL;DR: In this paper, the authors presented the first spectroscopic data from the Baryon Oscillation Spectroscopic Survey (BOSS) for the Sloan Digital Sky Survey III (SDSS-III) dataset.
Abstract: The Sloan Digital Sky Survey III (SDSS-III) presents the first spectroscopic data from the Baryon Oscillation Spectroscopic Survey (BOSS). This ninth data release (DR9) of the SDSS project includes 535,995 new galaxy spectra (median z ~ 0.52), 102,100 new quasar spectra (median z ~ 2.32), and 90,897 new stellar spectra, along with the data presented in previous data releases. These spectra were obtained with the new BOSS spectrograph and were taken between 2009 December and 2011 July. In addition, the stellar parameters pipeline, which determines radial velocities, surface temperatures, surface gravities, and metallicities of stars, has been updated and refined with improvements in temperature estimates for stars with T eff -0.5. DR9 includes new stellar parameters for all stars presented in DR8, including stars from SDSS-I and II, as well as those observed as part of the SEGUE-2. The astrometry error introduced in the DR8 imaging catalogs has been corrected in the DR9 data products. The next data release for SDSS-III will be in Summer 2013, which will present the first data from the APOGEE along with another year of data from BOSS, followed by the final SDSS-III data release in 2014 December.

1,623 citations


Journal ArticleDOI
TL;DR: The results indicate that internal integration strengthens the positive impacts of external integration on both delivery and flexibility performance, but the theory is not supported for either quality or cost performance.

477 citations


Journal ArticleDOI
TL;DR: In this article, the authors measured the Milky Way rotation curve over the Galactocentric range 4 kpc R 14 kpc from the first year of data from the Apache Point Observatory Galactic Evolution Experiment.
Abstract: We measure the Milky Way's rotation curve over the Galactocentric range 4 kpc R 14 kpc from the first year of data from the Apache Point Observatory Galactic Evolution Experiment. We model the line-of-sight velocities of 3365 stars in 14 fields with b = 0? between 30? ? l ? 210? out to distances of 10 kpc using an axisymmetric kinematical model that includes a correction for the asymmetric drift of the warm tracer population (? R 35 km s?1). We determine the local value of the circular velocity to be Vc (R 0) = 218 ? 6 km s?1 and find that the rotation curve is approximately flat with a local derivative between ?3.0 km s?1 kpc?1 and 0.4 km s?1 kpc?1. We also measure the Sun's position and velocity in the Galactocentric rest frame, finding the distance to the Galactic center to be 8 kpc 99 % confidence. We find an offset between the Sun's rotational velocity and the local circular velocity of 26 ? 3 km s?1, which is larger than the locally measured solar motion of 12 km s?1. This larger offset reconciles our value for Vc with recent claims that Vc 240 km s?1. Combining our results with other data, we find that the Milky Way's dark-halo mass within the virial radius is ~8 ? 1011 M ?.

441 citations


Journal ArticleDOI
TL;DR: In this article, the authors used meta-analytical techniques to assess the extent to which job burnout and employee engagement are independent and useful constructs, and found that dimension-level correlations between burnout, and engagement dimensions exhibit a similar pattern of association with correlates, and controlling for burnout in meta-regression equations significantly reduced the effect sizes associated with engagement.

329 citations


Journal ArticleDOI
TL;DR: Demand-side research has been used to explain and predict those managerial decisions that increase value creation within a value system as discussed by the authors, emphasizing product markets as key sources of value-creation strategies for firms.

312 citations


Journal ArticleDOI
TL;DR: A review of the literature on how firms engage in collaborative innovation with individual and business customers is provided in this paper, where the authors provide a synthesized conceptual framework from three existing models, and other streams of research, to organize this diverse body of literature.
Abstract: Collaborative innovation with customers or users is increasingly important for the development of new products and services. In this paper we provide a review of the literature, placing emphasis on how firms engage in collaborative innovation with individual and business customers. Our review develops a synthesized conceptual framework from three existing models, and other streams of research, to organize this diverse body of literature. We review studies from several disciplines including innovation, strategy, management, marketing and information technology. Although much of the literature assumes net positive benefits from such collaboration, we also discuss contrary perspectives. We highlight areas in which research is needed for greater understanding of the strategic issues and for managing the collaborative process, and provide suggestions for future studies.

273 citations


Journal ArticleDOI
TL;DR: This paper revisited the often neglected assumptions associated with the most common agreement statistic used to justify data aggregation and highlighted the potential misuse of rWG and RWG(J) as the sole statistic to justify aggregation to a higher level of analysis.
Abstract: Multilevel leadership researchers have predominantly applied either direct consensus or referent-shift consensus composition models when aggregating individual-level data to a higher level of analysis. Consensus composition assumes there is sufficient within-group agreement with respect to the leadership construct of interest; in the absence of agreement, the aggregate leadership construct is untenable. At the same time, guidelines to help leadership researchers make decisions regarding data aggregation issues have received little explicit attention. In particular, a discussion of how data aggregation decisions can enhance or obscure a study's theoretical contribution – a central focus of this article – has not been addressed thoroughly. Recognizing that empirical generalization depends on the accuracy with which aggregation decisions are applied, we revisit the often neglected assumptions associated with the most common agreement statistic used to justify data aggregation — rWG and rWG(J) (James, Demaree, and Wolf, 1984). Thereafter, using a dataset published as part of a Leadership Quarterly special issue (Bliese, Halverson, & Schriesheim, 2002), we highlight the potential misuse of rWG and rWG(J) as the sole statistic to justify aggregation to a higher level of analysis. We conclude with prescriptive implications for promoting consistency in the way multilevel leadership research is conducted and reported.

268 citations


Journal ArticleDOI
TL;DR: In this paper, the authors conceptualized a three-dimensional, Other Customer Perception (OCP) scale to assess individuals' perceptions of other customers during commercial transactions and demonstrated the impact of the OCP dimensions on consumers' approach and avoidance intentions.

260 citations


Journal ArticleDOI
TL;DR: In this paper, the authors presented new radial velocity measurements from the Bulge Radial Velocity Assay, a large-scale spectroscopic survey of M-type giants in the Galactic bulge/bar region.
Abstract: We present new radial velocity measurements from the Bulge Radial Velocity Assay, a large-scale spectroscopic survey of M-type giants in the Galactic bulge/bar region. The sample of ~4500 new radial velocities, mostly in the region –10° < l < +10° and b ≈ –6°, more than doubles the existent published data set. Our new data extend our rotation curve and velocity dispersion profile to +20°, which is ~2.8 kpc from the Galactic center. The new data confirm the cylindrical rotation observed at –6° and –8° and are an excellent fit to the Shen et al. N-body bar model. We measure the strength of the TiOe molecular band as a first step toward a metallicity ranking of the stellar sample, from which we confirm the presence of a vertical abundance gradient. Our survey finds no strong evidence of previously unknown kinematic streams. We also publish our complete catalog of radial velocities, photometry, TiO band strengths, and spectra, which is available at the Infrared Science Archive as well as at UCLA.

252 citations


Journal ArticleDOI
TL;DR: Examination of how and why economic recessions influence women's consumer behavior revealed that recessionary cues consistently increased women's desire for products that increase attractiveness to mates--the first experimental demonstration of the lipstick effect.
Abstract: Although consumer spending typically declines in economic recessions, some observers have noted that recessions appear to increase women's spending on beauty products--the so-called lipstick effect. Using both historical spending data and rigorous experiments, the authors examine how and why economic recessions influence women's consumer behavior. Findings revealed that recessionary cues--whether naturally occurring or experimentally primed--decreased desire for most products (e.g., electronics, household items). However, these cues consistently increased women's desire for products that increase attractiveness to mates--the first experimental demonstration of the lipstick effect. Additional studies show that this effect is driven by women's desire to attract mates with resources and depends on the perceived mate attraction function served by these products. In addition to showing how and why economic recessions influence women's desire for beauty products, this research provides novel insights into women's mating psychology, consumer behavior, and the relationship between the two.

230 citations


Journal ArticleDOI
TL;DR: In this paper, the authors applied affective events theory (AET) as a framework for understanding the relationship between the shared authentic leadership of new venture top management teams (TMTs) and the performance of their firms.

Journal ArticleDOI
TL;DR: Using the Theory of Reasoned Action (TRA) as a guiding framework, this article presented a structural equation model that tested the relationships between carbon and environmental knowledge, environmental attitude and behaviour using a sample of US consumers.
Abstract: Global warming and carbon emissions have gained international attention. However, it would appear that consumers are still unclear about what it encompasses and how it relates to their individual behaviour. Using the Theory of Reasoned Action (TRA) as a guiding framework, this study presents a structural equation model that tests the relationships between carbon and environmental knowledge, environmental attitude and behaviour using a sample of US consumers. The findings of the research suggest that a positive relationship was found between general and carbon-specific knowledge, attitude towards the environment, and general and carbon-specific behaviours. Therefore, general and carbon-specific environmental behaviours are related and may be driven by general attitudes and knowledge (i.e. both carbon-specific and general environmental knowledge). The implications of the study would suggest that marketers, working in tandem with government policymakers, need to focus efforts on developing consumers' knowledge about specific sub-issues, such as global warming. However, additional research needs to be undertaken to develop marketing communication that accurately reflects the environmental impact of consumption behaviour, thereby allowing for considered consumption.

Journal ArticleDOI
TL;DR: In this article, the authors test whether Standard and Poor's assigns higher bond ratings after switching from investor-pay to issuer-pay fees in 1974, using Moody's rating for the same bond as a benchmark.

Journal ArticleDOI
TL;DR: Addressing inadequate knowledge and negative attitudes about MAT may increase its adoption, but better linkages to community pharmacotherapy during the reentry period might overcome other issues, including security, liability, staffing, and regulatory concerns.
Abstract: Medication-assisted treatment (MAT) is underutilized in the treatment of drug-dependent, criminal justice populations. This study surveyed criminal justice agencies affiliated with the Criminal Justice Drug Abuse Treatment Studies (CJ-DATS) to assess use of MAT and factors influencing use of MAT. A convenience sample (N = 50) of criminal justice agency respondents (e.g., jails, prisons, parole/probation, and drug courts) completed a survey on MAT practices and attitudes. Pregnant women and individuals experiencing withdrawal were most likely to receive MAT for opiate dependence in jail or prison, whereas those reentering the community from jail or prison were the least likely to receive MAT. Factors influencing use of MAT included criminal justice preferences for drug-free treatment, limited knowledge of the benefits of MAT, security concerns, regulations prohibiting use of MAT for certain agencies, and lack of qualified medical staff. Differences across agency type in the factors influencing use and perceptions of MAT were also examined. MAT use is largely limited to detoxification and maintenance of pregnant women in criminal justice settings. Use of MAT during the community reentry period is minimal. Addressing inadequate knowledge and negative attitudes about MAT may increase its adoption, but better linkages to community pharmacotherapy during the reentry period might overcome other issues, including security, liability, staffing, and regulatory concerns. The CJ-DATS collaborative MAT implementation study to address inadequate knowledge, attitudes, and linkage will be described.

Journal ArticleDOI
TL;DR: In this paper, the authors revisit and update arguments recently advanced by Hunt and Davis (2008) in this journal concerning which theoretical perspectives may provide the most useful "lenses" for SCM scholars interested in addressing these critical questions.
Abstract: When and how can supply chain management (SCM) be a source of long-term competitive advantage for the firm? We revisit and update arguments recently advanced by Hunt and Davis (2008) in this journal concerning which theoretical perspectives — the resource-based view of strategy or resource-advantage theory — may provide the most useful “lenses” for SCM scholars interested in addressing these critical questions. In this brief article we suggest that SCM research addressing questions of competitive advantage can be enhanced by a more rigorous definition of resources and by a more system-wide view of competition. We also recommend that the nascent demand-side perspective on strategic management can serve to provide new insights and a more complete understanding of SCM's role in competition. While the existing SCM literature offers a few examples of this perspective, in our opinion this remains an unfulfilled opportunity for SCM scholars.

Journal ArticleDOI
TL;DR: In this paper, the authors examined how shoppers vary in terms of deeper motives to seek control or intimacy with others in retail mall settings, and whether these motives influence shopping orientations.
Abstract: While a few researchers have started to chip away at the notion that retail density is always negative, extant studies do not empirically address the question of why some shoppers respond negatively to a specific level of density while others respond positively. We examine this issue by drawing upon field theory (Lewin 1939) to shed light on how shoppers vary in terms of deeper motives (McClelland 1953) to seek control or intimacy with others in retail mall settings, and whether these motives influence shopping orientations. Shopping orientation is then hypothesized to affect perceptions of crowding, and, in turn, subsequent affective responses to the mall shopping experience. Moreover, we examine whether individual differences (gender and age) can help retailers segment those with different shopping orientations and the motives that influence these orientations. We found that task and social shopping orientations were influenced by deeper motives for control and intimacy. The causal relationships between shopping motive, shopping orientation, and consumers’ affective responses of stress and excitement were also discovered. Finally, we address theoretical and managerial implications of our results.

Journal ArticleDOI
TL;DR: In this paper, the authors compared female students' perceptions of the value of advertising on social network sites (SNSs) to their perceptions of television advertising, using an online questionnaire among students from three major universities in USA, as well as SNSs (Facebook, LinkedIn, and Twitter).
Abstract: Purpose – The purpose of this paper is to compare female students' perceptions of the value of advertising on social network sites (SNSs) to their perceptions of the value of television advertisingDesign/methodology/approach – An online questionnaire was fielded among students from three major universities in the USA, as well as SNSs (Facebook, LinkedIn, and Twitter) The final sample (n=259) was comprised of female students who had used social media and television during the past month The authors developed two structural equation models using Amos 18 statistical softwareFindings – The analysis indicated that Ducoffe's Ad Value model does not provide a good fit for assessing advertising value in social media or television While Irritation was a factor in assessing Attitude toward advertising, the respondents assessed ad value on the basis of Entertainment (higher for social media) and Informativeness (higher for television)Research limitations/implications – In examining the relative importance of e

Journal ArticleDOI
TL;DR: It is shown that one injection of LPS leads to sickness behavior, but 7 consecutive days does not, indicating tolerance to the endotoxin, which resulted in increased Aβ1-42 in the hippocampus and cognitive deficits in mice.

Journal ArticleDOI
TL;DR: In this article, a new set of extended emission-line regions (EELRs) was identified, which can trace both the illumination pattern of escaping radiation and its history over the light-travel time from the active galactic nuclei to the gas.
Abstract: Some active galactic nuclei (AGN) are surrounded by extended emission-line regions (EELRs), which trace both the illumination pattern of escaping radiation and its history over the light-travel time from the AGN to the gas. From a new set of such EELRs, we present evidence that the AGN in many Seyfert galaxies undergo luminous episodes 0.2–2×10 5 years in duration. Motivated by the discovery of the spectacular nebula known as Hanny’s Voorwerp, ionized by a powerful AGN which has apparently faded dramatically within � 10 5 years, Galaxy Zoo volunteers have carried out both targeted and serendipitous searches for similar emission-line clouds around lowredshift galaxies. We present the resulting list of candidates and describe spectroscopy identifying 19 galaxies with AGN-ionized regions at projected radii rproj > 10 kpc. This search recovered known EELRs (such as Mkn 78, Mkn 266, and NGC 5252) and identified additional previously unknown cases, one with detected emission to r = 37 kpc. One new Sy 2 was identified. At least 14/19 are in interacting or merging systems, suggesting that tidal tails are a prime source of distant gas out of the galaxy plane to be ionized by an AGN. We see a mix of one- and two-sided structures, with observed cone angles from 23–112 ◦ . We consider the energy balance in the ionized clouds, with lower and upper bounds on ionizing luminosity from recombination and ionizationparameter arguments, and estimate the luminosity of the core from the far-infrared data. The implied ratio of ionizing radiation seen by the clouds to that emitted by the nucleus, on the assumption of a nonvariable nuclear source, ranges from 0.02 to > 12; 7/19 exceed unity. Small values fit well with a heavily obscured AGN in which only a small fraction of the ionizing output escapes to be traced by surrounding gas. However, large values may require that the AGN has faded over tens of thousands of years, giving us several examples of systems in which such dramatic long-period variation has occurred; this is the only current technique for addressing these timescales in AGN history. The relative numbers of faded and non-faded objects we infer, and the projected extents of the ionized regions, give our estimate (0.2–2×10 5 years ) for

Journal ArticleDOI
TL;DR: Triazine adducts with paclitaxel, camptothecin, brefeldin A, and desferrioxamine have been prepared and assessed and show promising activity in vivo.

Journal ArticleDOI
TL;DR: RT reduced markers of subclinical inflammation in circulation in obese, postmenopausal women in the absence of changes in body composition and did not influence inflammatory biomarker gene expression in whole blood or subcutaneous adipose tissue.
Abstract: AB Purpose: Aerobic exercise is frequently prescribed to reduce inflammatory-related disease (cardiovascular disease and diabetes) risk. Resistance training (RT), however, may be key to maximizing anti-inflammatory benefits of consistent exercise. We examined the influence of RT on inflammatory biomarkers in obese, postmenopausal women. Methods: Twenty-three women (65.6 +/- 2.6 yr; body mass index, 33 kg[middle dot]m-2) underwent 12 wk of RT (3 sets, 10 exercises, 3x per week, 8-12 repetition maximum (RM), resistance exercise (EX), N = 11) or social interaction intervention (SI, stretching, knitting, health lectures, 2x per week, control group (CON), N = 12). Both before (BT) and after (AT) RT or SI, blood was collected before (PR), immediately (PO), 2 h (2H), and 24 h (24H) after a single resistance exercise bout (RE) in EX and at the same time points in nonexercise, resting CON. For all time points, blood was analyzed for IL-6, leptin, and lipopolysaccharide (LPS)-stimulated tumor necrosis factor-[alpha] (TNF-[alpha]) (LPS-TNF) and IL-10 (LPS-IL10). PR samples were also examined for C-reactive protein, TNF-[alpha], and adiponectin, and mRNA expression of toll-like receptor 4 (TLR4) and MC1R. Subcutaneous adipose tissue was extracted BT and AT and analyzed for mRNA expression of monocyte chemotactic protein-1, leptin, CD68, and TLR4. Results: RT improved strength (44%) and reduced circulating C-reactive protein (-33%), leptin (-18%) and TNF-[alpha] (-29%) with no change in body composition. IL-6 decreased after SI in CON (-17%). LPS-TNF increased after SI or RT (CON +26%, EX +67%, respectively), whereas LPS-IL10 decreased in CON (-28%) but increased in EX (+20%). RT did not influence inflammatory biomarker gene expression in whole blood or subcutaneous adipose tissue. A single RE bout augmented LPS-TNF and LPS-IL10 at 24H in EX, particularly AT. Conclusion: RT reduced markers of subclinical inflammation in circulation in obese, postmenopausal women in the absence of changes in body composition. Chronic RT also enhanced response to endotoxin challenge both at rest (PR) and 24 h after an acute RE bout (24H). (C)2012The American College of Sports Medicine

Journal ArticleDOI
31 Oct 2012-PLOS ONE
TL;DR: This study indicated that MB could attenuate superoxide production by functioning as an alternative mitochondrial electron transfer carrier and as a regenerable anti-oxidant in mitochondria.
Abstract: Methylene blue (MB), the first lead chemical structure of phenothiazine and other derivatives, is commonly used in diagnostic procedures and as a treatment for methemoglobinemia. We have previously demonstrated that MB could function as an alternative mitochondrial electron transfer carrier, enhance cellular oxygen consumption, and provide protection in vitro and in rodent models of Parkinson’s disease and stroke. In the present study, we investigated the structure-activity relationships of MB in vitro using MB and six structurally related compounds. MB reduces mitochondrial superoxide production via alternative electron transfer that bypasses mitochondrial complexes I-III. MB mitigates reactive free radical production and provides neuroprotection in HT-22 cells against glutamate, IAA and rotenone toxicity. Distinctly, MB provides no protection against direct oxidative stress induced by glucose oxidase. Substitution of a side chain at MB’s 10-nitrogen rendered a 1000-fold reduction of the protective potency against glutamate neurototoxicity. Compounds without side chains at positions 3 and 7, chlorophenothiazine and phenothiazine, have distinct redox potentials compared to MB and are incapable of enhancing mitochondrial electron transfer, while obtaining direct antioxidant actions against glutamate, IAA, and rotenone insults. Chlorophenothiazine exhibited direct antioxidant actions in mitochondria lysate assay compared to MB, which required reduction by NADH and mitochondria. MB increased complex IV expression and activity, while 2-chlorphenothiazine had no effect. Our study indicated that MB could attenuate superoxide production by functioning as an alternative mitochondrial electron transfer carrier and as a regenerable anti-oxidant in mitochondria.

Journal ArticleDOI
TL;DR: The overlooked issue of how certain strategic-level, interindustry diversification options might increase consumer utility is explored, and a mathematical model is developed showing how demand-side synergies can create unique business value is developed.
Abstract: We explore the overlooked issue of how certain strategic-level, interindustry diversification options might increase consumer utility. Discussions of inter-industry diversification typically focus on producer synergies obtainable from economies of scope or from skill transfer across business units. Discussions of intra-industry product diversification—generally, the province of marketing—typically focus on synergies obtainable from product bundling, which lowers producer costs or provides convenience for consumers. We take a different tack by linking interindustry diversification and consumer utility. We first separately examine two possible consumer benefits of interindustry diversification: (1) facilitating consumers' accomplishment of two tasks simultaneously or (2) attracting diverse consumer groups to a common platform when intergroup externalities exist. We then assess a simple empirical context that shows potential for simultaneous consumer utilities and two-sided market utility together. We analyze this context and concurrently develop a mathematical model showing how these demand-side synergies can create unique business value. We next introduce asymmetric preferences among consumer subgroups, and we refine our arguments by comparing their conclusions with the empirical data. We learn that combinations of otherwise mundane (i.e., commonplace) assets can create consumer value—“superior” assets are not necessary. Moreover, common ownership is necessary for the pricing flexibility required to deliver (and capture) maximum value through interindustry diversification, especially when consumer groups' preferences may change; the negotiations and settling up required for cooperation through alliances will, without common ownership, increase costs and reduce responsiveness. We discuss the sustainability of demand-side advantages and the implications of these ideas for future research and practice.

Journal ArticleDOI
TL;DR: Results indicate that children in the groups that included therapy dogs showed significant decreases in trauma symptoms including anxiety, depression, anger, post-traumatic stress disorder, dissociation, and sexual concerns.
Abstract: This study evaluates and compares the effectiveness of three group interventions on trauma symptoms for children who have been sexually abused. All of the groups followed the same treatment protocol, with two of them incorporating variations of animal-assisted therapy. A total of 153 children ages 7 to 17 who were in group therapy at a Child Advocacy Center participated in the study. Results indicate that children in the groups that included therapy dogs showed significant decreases in trauma symptoms including anxiety, depression, anger, post-traumatic stress disorder, dissociation, and sexual concerns. In addition, results show that children who participated in the group with therapeutic stories showed significantly more change than the other groups. Implications and suggestions for further research are discussed.

Journal ArticleDOI
TL;DR: This work examined the effects of fit between leader consideration and initiating structure needed and received on employees' work-related attitudes (i.e., trust in the supervisor, job satisfaction, and affective commitment to the organization).
Abstract: We examined the effects of fit between leader consideration and initiating structure needed and received on employees' work-related attitudes (i.e., trust in the supervisor, job satisfaction, and affective commitment to the organization). Consistent with predictions that derive from the person-environment fit research tradition, results from Study 1 suggested that deficient amounts of both leadership behaviors were associated with unfavorable attitudinal outcomes. However, while excess levels of consideration were associated with favorable attitudinal outcomes, excess levels of initiating structure were associated with unfavorable attitudes, and for both forms of leadership, higher levels of absolute fit were associated with more favorable outcomes. Results from Study 2 suggested that attitudes generated by the fit between leadership needed and received influence employees' organizational citizenship behavior as reported by their supervisors. The relationship between consideration needed and received and subordinates' organizational citizenship behavior relating to individuals (OCBI) and organizational citizenship behavior relating to the organization itself (OCBO) was partially mediated by employees' trust in the supervisor, while the relationship between initiating structure needed and received and OCBI was fully mediated by trust in the supervisor, and for OCBO was partially mediated.

Journal ArticleDOI
TL;DR: This review focuses on the application of thioflavin T for determining the efficiency of small molecule inhibitors of Aβ aggregation and addresses potential reasons that might be associated with the false positive effects in an effort to increase reliability of dye-binding assays.
Abstract: Dye-binding assays, such as those utilizing Congo red and thioflavin T, are among the most widely used tools to probe the aggregation of amyloidogenic biomolecules and for the evaluation of small molecule inhibitors of amyloid aggregation and fibrillization. A number of recent reports have indicated that these dye-binding assays could be prone to false positive effects when assessing inhibitors’ potential toward Aβ peptides, species involved in Alzheimer’s disease. Specifically, this review focuses on the application of thioflavin T for determining the efficiency of small molecule inhibitors of Aβ aggregation and addresses potential reasons that might be associated with the false positive effects in an effort to increase reliability of dye-binding assays.

Journal ArticleDOI
TL;DR: In this paper, the authors introduce the notion that the energy of individuals can manifest as a higher-level, collective construct, and investigate the viability and importance of the collective energy construct as assessed by a new survey instrument (PEM).
Abstract: We introduce the notion that the energy of individuals can manifest as a higher-level, collective construct. To this end, we conducted four independent studies to investigate the viability and importance of the collective energy construct as assessed by a new survey instrument—the productive energy measure (PEM). Study 1 (n = 2208) included exploratory and confirmatory factor analyses to explore the underlying factor structure of PEM. Study 2 (n = 660) cross-validated the same factor structure in an independent sample. In study 3, we administered the PEM to more than 5000 employees from 145 departments located in five countries. Results from measurement invariance, statistical aggregation, convergent, and discriminant-validity assessments offered additional support for the construct validity of PEM. In terms of predictive and incremental validity, the PEM was positively associated with three collective attitudes—units' commitment to goals, the organization, and overall satisfaction. In study 4, we explored the relationship between the productive energy of firms and their overall performance. Using data from 92 firms (n = 5939employees), we found a positive relationship between the PEM (aggregated to the firm level) and the performance of those firms. Copyright © 2011 John Wiley & Sons, Ltd.

Journal ArticleDOI
TL;DR: Results indicated that adolescents from ages 14 to 15 years were the most sedentary and spent the least amount of time in light and moderate-to-vigorous physical activity.
Abstract: The purpose of this study was to examine the physical activity patterns of children with Down syndrome. A cross-sectional approach and accelerometry were used to measure the time children with Down syndrome (N = 104) spent in sedentary, light, and moderate-to-vigorous physical activity. Results indicated that adolescents from ages 14 to 15 years were the most sedentary and spent the least amount of time in light and moderate-to-vigorous physical activity. A general trend of decreasing physical activity as children increase in age was found. This trend is similar to that found among typically developing youth. Participants in this study were found to spend a majority of their day engaged in sedentary activities. Results indicate that most participants were not accumulating the recommended 60 minutes of moderate or vigorous physical activity.

Posted Content
TL;DR: In this paper, a behavioral perspective on investor reactions to acquisition announcements is developed, which relaxes the assumption of investors making objective, rational-deductive calculations. But the traditional financial economic rationale on which it is based has led scholars to assume away the behavioral mechanisms underlying investor reactions.
Abstract: Although event-study methodology is invaluable to strategic management research, we argue that the traditional financial economic rationale on which it is based has led scholars to assume away the behavioral mechanisms underlying investor reactions. Building on behavioral theory from management, psychology, and economics, we set out to develop a behavioral perspective on investor reactions to acquisition announcements — one that relaxes the assumption of investors making objective, rational-deductive calculations. Given the information asymmetry they face, we theorize that investors (1) infer management’s perception of an acquisition’s synergistic potential from the premium it pays, and (2) draw on additional public information to assess the reliability of that perception. Using a multi-industry sample of acquisitions by North American firms, we find considerable support for our behavioral framework.

Journal ArticleDOI
TL;DR: In this paper, the authors leverage the research on organizational improvement and data use to discuss three specific organizational areas in which these districts may improve: establishing common understandings, professional learning for using data, and computer data systems.
Abstract: In the United States, effective data use is proving to be a vexing problem. In response, scholars have recently begun viewing this as a systemic problem, believing there are actions a school district may take to make data use more efficient and tenable throughout the organization. In this article, we add to the knowledge of how school organizations can more effectively use data for educational improvement. Through the lens of the Data-Informed District, we leverage the research on organizational improvement and data use to discuss 3 specific organizational areas in which these districts may improve: establishing common understandings, professional learning for using data, and computer data systems.