Institution
The Chinese University of Hong Kong
Education•Hong Kong, China•
About: The Chinese University of Hong Kong is a education organization based out in Hong Kong, China. It is known for research contribution in the topics: Population & Cancer. The organization has 43411 authors who have published 93672 publications receiving 3066651 citations.
Topics: Population, Cancer, Poison control, Randomized controlled trial, China
Papers published on a yearly basis
Papers
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TL;DR: By considering the flows associated with different entities within the ecosystem, recent Operations Research/Management Science research developments are classified and summarized and several gaps for future research are identified.
392 citations
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TL;DR: The advantageous properties and potential of phthalocyanines as advanced photosensitisers for photodynamic therapy of cancer are highlighted in this tutorial review.
Abstract: Phthalocyanines exhibit superior photoproperties that make them a surely attractive class of photosensitisers for photodynamic therapy of cancer. Several derivatives are at various phases of clinical trials, and efforts have been put continuously to improve their photodynamic efficacy. To this end, various strategies have been applied to develop advanced phthalocyanines with optimised photoproperties, dual therapeutic actions, tumour-targeting properties and/or specific activation at tumour sites. The advantageous properties and potential of phthalocyanines as advanced photosensitisers for photodynamic therapy of cancer are highlighted in this tutorial review.
392 citations
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TL;DR: This work establishes a general relation between the fidelity and structure factor of the driving term in a Hamiltonian through the concept of fidelity susceptibility, facilitates the evaluation of fidelity in terms of susceptibility using well-developed techniques, such as density matrix renormalization group for the ground state, or Monte Carlo simulations for the states in thermal equilibrium.
Abstract: Motivated by the growing importance of fidelity in quantum critical phenomena, we establish a general relation between the fidelity and structure factor of the driving term in a Hamiltonian through the concept of fidelity susceptibility. Our discovery, as shown by some examples, facilitates the evaluation of fidelity in terms of susceptibility using well-developed techniques, such as density matrix renormalization group for the ground state, or Monte Carlo simulations for the states in thermal equilibrium.
392 citations
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TL;DR: The peroral endoscopic transgastric approach to ligation of the Fallopian tubes with long-term survival is technically feasible and safe in a porcine model and has potential for a wide array of diagnostic and therapeutic procedures.
392 citations
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TL;DR: PDT with verteporfin is successful in stopping the fluorescein leakage in all six patients without recurrence of CSC and the ICG-A findings of choroidal vascular remodelling and decreased choroid permeability after PDT are encouraging.
Abstract: Aims: To evaluate the changes in the choroidal vasculature in central serous chorioretinopathy (CSC) after photodynamic therapy (PDT) with verteporfin and to assess its potential role as a treatment option. Methods: A prospective, non-comparative, interventional study was performed in eyes with persistent CSC or chronic CSC that had fluorescein leakage at the fovea. All eyes received one single session of PDT with verteporfin (6 mg/m 2 body surface area) followed by application of 50 J/cm 2 laser at 689 nm. The laser spot size was guided by findings in ICG-A. Results: Six eyes from six patients with a mean follow up of 12.7 months were analysed. Narrowing of the original dilated choroidal vessels and decrease in extravascular leakage could be demonstrated in all (100%) PDT treated eyes. 3 months after PDT, the mean diameter of the dilated choroidal vessel reduced from 546 μm to 371 μm (p = 0.028). Five (83%) patients had improvement in visual symptoms and best corrected visual acuity. Fluorescence leakage stopped at the 1 month follow up in five eyes (83%) and at 3 months in all six eyes (100%). One eye developed choroidal neovascularisation at 3 month follow up. There was no other serious ocular or systemic complication. Conclusions: PDT is successful in stopping the fluorescein leakage in all six patients without recurrence of CSC. The ICG-A findings of choroidal vascular remodelling and decreased choroidal permeability after PDT are encouraging. As the sample size is small and the mean follow up period is short, further trials of PDT with verteporfin for CSC are required to address the optimal parameters in ensuring longer term safety and efficacy outcome.
392 citations
Authors
Showing all 43993 results
Name | H-index | Papers | Citations |
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Michael Marmot | 193 | 1147 | 170338 |
Jing Wang | 184 | 4046 | 202769 |
Jiaguo Yu | 178 | 730 | 113300 |
Yang Yang | 171 | 2644 | 153049 |
Mark Gerstein | 168 | 751 | 149578 |
Gang Chen | 167 | 3372 | 149819 |
Jun Wang | 166 | 1093 | 141621 |
Jean Louis Vincent | 161 | 1667 | 163721 |
Wei Zheng | 151 | 1929 | 120209 |
Rui Zhang | 151 | 2625 | 107917 |
Ben Zhong Tang | 149 | 2007 | 116294 |
Kypros H. Nicolaides | 147 | 1302 | 87091 |
Thomas S. Huang | 146 | 1299 | 101564 |
Galen D. Stucky | 144 | 958 | 101796 |
Joseph J.Y. Sung | 142 | 1240 | 92035 |