Tohoku University

About: Tohoku University is a education organization based out in Sendai, Japan. It is known for research contribution in the topics: Magnetization & Population. The organization has 72116 authors who have published 170791 publications receiving 3941714 citations. The organization is also known as: Tōhoku daigaku.

Unified gauge theories and the baryon number of the universe

Abstract: I suggest that the dominance of matter over antimatter in the present universe is a consequence of baryon-number--nonconserving reactions in the very early fireball. Unified gauge theories of weak, electromagnetic, and strong interactions provide a basis for such a conjecture and a computation in specific SU(5) models gives a small ratio of baryon- to photon-number density in rough agreement with observation.

Development of General-Purpose Particle and Heavy Ion Transport Monte Carlo Code

Abstract: The high-energy particle transport code NMTC/JAM, which has been developed at JAERI, was improved for the high-energy heavy ion transport calculation by incorporating the JQMD code, the SPAR code and the Shen formula. The new NMTC/JAM named PHITS (Particle and Heavy-Ion Transport code System) is the first general-purpose heavy ion transport Monte Carlo code over the incident energies from several MeV/nucleon to several GeV/nucleon.

Solar neutrino measurements in Super-Kamiokande-II

Abstract: The results of the second phase of the Super-Kamiokande solar neutrino measurement are presented and compared to the first phase. The solar neutrino flux spectrum and time variation as well as oscillation results are statistically consistent with the first phase and do not show spectral distortion. The time-dependent flux measurement of the combined first and second phases coincides with the full period of solar cycle 23 and shows no correlation with solar activity. The measured {sup 8}B total flux is (2.38{+-}0.05(stat.){sub -0.15}{sup +0.16}(sys.))x10{sup 6} cm{sup -2} s{sup -1} and the day-night difference is found to be (-6.3{+-}4.2(stat.){+-}3.7(sys.))%. There is no evidence of systematic tendencies between the first and second phases.

Discovery of the negative regulator of Nrf2, keap1: A historical overview

Abstract: An antioxidant response element (ARE) or an electrophile responsive element (EpRE) regulate the transcriptional induction of a battery of drug-detoxifying enzymes that are protective against electrophiles. Based on the high similarity of the ARE consensus sequence to an erythroid gene regulatory element NF-E2 binding site, we have found that the transcription factor Nrf2 is indispensable for the ARE-mediated induction of drug-metabolizing enzymes. Recent genome-wide analysis demonstrated that Nrf2 regulates hundreds of genes that are involved in the cytoprotective response against oxidative stress. In-depth analysis of Nrf2 regulatory mechanisms has led us to the discovery of a novel protein, which we have named Keap1. Keap1 suppresses Nrf2 activity by specifically binding to its evolutionarily conserved N-terminal Neh2 regulatory domain. In this review article, we summarize the findings and observations that have lead to the discovery of the Nrf2–Keap1 system. Furthermore, we briefly discuss the...