Tokyo Institute of Technology

About: Tokyo Institute of Technology is a education organization based out in Tokyo, Tôkyô, Japan. It is known for research contribution in the topics: Catalysis & Thin film. The organization has 46775 authors who have published 101656 publications receiving 2357893 citations. The organization is also known as: Tokyo Tech & Tokodai.

Design and Performance of a Bidirectional Isolated DC–DC Converter for a Battery Energy Storage System

Abstract: This paper describes the design and performance of a 6-kW, full-bridge, bidirectional isolated dc-dc converter using a 20-kHz transformer for a 53.2-V, 2-kWh lithium-ion (Li-ion) battery energy storage system. The dc voltage at the high-voltage side is controlled from 305 to 355 V, as the battery voltage at the low-voltage side (LVS) varies from 50 to 59 V. The maximal efficiency of the dc-dc converter is measured to be 96.0% during battery charging, and 96.9% during battery discharging. Moreover, this paper analyzes the effect of unavoidable dc-bias currents on the magnetic-flux saturation of the transformer. Finally, it provides the dc-dc converter loss breakdown with more focus on the LVS converter.

Formation of Protoplanet Systems and Diversity of Planetary Systems

Abstract: We investigate the formation of protoplanet systems from planetesimal disks by global (N = 5000 and 10,000 and 0.5 AU 2. The growth timescale increases with a but decreases with Σ1. Based on the oligarchic growth model and the conventional Jovian planet formation scenario, we discuss the diversity of planetary systems. Jovian planets can form in the disk range where the contraction timescale of planetary atmosphere and the growth timescale of protoplanets (cores) are shorter than the lifetime of the gas disk. We find that for the disk lifetime ~108 yr, several Jovian planets would form from massive disks with Σ1 30 with Uranian planets outside the Jovian planets. Only terrestrial and Uranian planets would form from light disks with Σ1 3. Solar system-like planetary systems would form from medium disks with Σ1 10.

Shape memory alloy servo actuator system with electric resistance feedback and application for active endoscope

Abstract: A control system for a shape memory alloy (SMA) servo actuator, and its application to a unique medical tool, are considered. It is thought that the electric resistance value of an SMA can be utilized to monitor the transformation of the SMA directly. Therefore, an antagonistic transformation control scheme using electric resistance feedback is proposed and is verified by several experiments. This control scheme reduces the open-loop hysteresis of an SMA actuator and improves greatly its robustness against heat disturbance due to changes in the cooling condition. Research into the application of the method in an active endoscope is reported. It consists of five segments of 13 mm diameter, 40 mm length each. The bending angle of each segment can be controlled individually from outside by using antagonistic electric resistance feedback without any motion sensors. A model for smooth insertion to the colon is verified. >

Kinetic measurements of DNA hybridization on an oligonucleotide-immobilized 27-MHz quartz crystal microbalance.

Abstract: A highly sensitive 27-MHz quartz-crystal microbalance, on which a 10−30-mer oligonucleotide was immobilized as a probe molecule, was employed to detect hybridization of complementary oligonucleotides in aqueous solution. From frequency decreases (mass increases due to the hybridization) with passage of time, kinetic parameters such as association constants (Ka) and binding and dissociation rate constants (k1 and k-1) could be obtained, as well as binding (hybridization) amount at the nanogram level (Δm). Kinetic studies were carried out by changing various parameters: (i) the immobilization method of a probe oligonucleotide on Au electrode, (ii) number of mismatching bases in sequences of target oligonucleotides, (iii) length of both probe and target oligonucleotides, (iv) hybridization temperature, and (v) ionic strength in solution. The obtained results were compared with those obtained by a surface plasmon resonance method using a BIAcore system.

Erasing genomic imprinting memory in mouse clone embryos produced from day 11.5 primordial germ cells.

Abstract: Genomic imprinting is an epigenetic mechanism that causes functional differences between paternal and maternal genomes, and plays an essential role in mammalian development. Stage-specific changes in the DNA methylation patterns of imprinted genes suggest that their imprints are erased some time during the primordial germ cell (PGC) stage, before their gametic patterns are re-established during gametogenesis according to the sex of individuals. To define the exact timing and pattern of the erasure process, we have analyzed parental-origin-specific expression of imprinted genes and DNA methylation patterns of differentially methylated regions (DMRs) in embryos, each derived from a single day 11.5 to day 13.5 PGC by nuclear transfer. Cloned embryos produced from day 12.5 to day 13.5 PGCs showed growth retardation and early embryonic lethality around day 9.5. Imprinted genes lost their parental-origin-specific expression patterns completely and became biallelic or silenced. We confirmed that clones derived from both male and female PGCs gave the same result, demonstrating the existence of a common default state of genomic imprinting to male and female germlines. When we produced clone embryos from day 11.5 PGCs, their development was significantly improved, allowing them to survive until at least the day 11.5 embryonic stage. Interestingly, several intermediate states of genomic imprinting between somatic cell states and the default states were seen in these embryos. Loss of the monoallelic expression of imprinted genes proceeded in a step-wise manner coordinated specifically for each imprinted gene. DNA demethylation of the DMRs of the imprinted genes in exact accordance with the loss of their imprinted monoallelic expression was also observed. Analysis of DNA methylation in day 10.5 to day 12.5 PGCs demonstrated that PGC clones represented the DNA methylation status of donor PGCs well. These findings provide strong evidence that the erasure process of genomic imprinting memory proceeds in the day 10.5 to day 11.5 PGCs, with the timing precisely controlled for each imprinted gene. The nuclear transfer technique enabled us to analyze the imprinting status of each PGC and clearly demonstrated a close relationship between expression and DNA methylation patterns and the ability of imprinted genes to support development.