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Institution

Tokyo University of Science

EducationTokyo, Japan
About: Tokyo University of Science is a education organization based out in Tokyo, Japan. It is known for research contribution in the topics: Catalysis & Thin film. The organization has 15800 authors who have published 24147 publications receiving 438081 citations. The organization is also known as: Tōkyō Rika Daigaku & Science University of Tokyo.


Papers
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Journal ArticleDOI
TL;DR: The co-immobilization of both antibody and PEG on the magnetic bead surfaces reduced the nonspecific adsorption of proteins from cell lysates and the sensitivity of the antibody on the surface was enhanced significantly when the PEG tethered chain was constructed in between the surface antibodies.

104 citations

Journal ArticleDOI
TL;DR: A connection between the chirality of amino acids and sugars is described, and Amplification of ee was observed in the aaminoxylation of an aldehyde using proline as catalyst to generate a key intermediate of sugars.
Abstract: How homochiral amino acids and sugars arose out of a presumably prochiral prebiotic environment is a puzzling question, to which many answers have been proposed: for example, absolute asymmetric synthesis with circularly polarized light, photoreactions in chiral crystals, and asymmetric automultiplication with asymmetric autocatalysis, as exemplified by the recent work of Soai et al. There are reports describing a connection between the chirality of amino acids and sugars: Amplification of ee was observed in the aaminoxylation of an aldehyde using proline as catalyst to generate a key intermediate of sugars, while amino acids

103 citations

Journal ArticleDOI
TL;DR: A ZnCl(2)-catalyzed three-component coupling reaction involving a variety of functionalized enamines, triethyl orthoformate, and ammonium acetate is developed, which leads to the production of 4,5-disubstituted pyrimidine derivatives in a single step.

103 citations

Journal ArticleDOI
TL;DR: Analyses of cells in the boundary region revealed that endoreduplication precedes rapid cell elongation in roots, and a boundary cell with 4C nuclei exhibiting the whole pattern of EdU signals was found.
Abstract: Plant roots consist of a meristematic zone of mitotic cells and an elongation zone of rapidly expanding cells, in which DNA replication often occurs without cell division, a process known as endoreduplication. The duration of the cell cycle and DNA replication, as measured by 5-ethynyl-2′-deoxy-uridine (EdU) incorporation, differed between the two regions (17 h in the meristematic zone, 30 h in the elongation zone). Two distinct subnuclear patterns of EdU signals, whole and speckled, marked nuclei undergoing DNA replication at early and late S phase, respectively. The boundary region between the meristematic and elongation zones was analysed by a combination of DNA replication imaging and optical estimation of the amount of DNA in each nucleus (C-value). We found a boundary cell with 4C nuclei exhibiting the whole pattern of EdU signals. Analyses of cells in the boundary region revealed that endoreduplication precedes rapid cell elongation in roots.

103 citations

Journal ArticleDOI
TL;DR: It is shown that ASB proteins interact with Cul5–Rbx2 but neither Cul2 nor Rbx1 in cells, and these findings suggest that the ASB family proteins interactions with Cul 5–R bx2 to form E3 Ub ligases and play significant roles via a ubiquitination‐mediated pathway.

103 citations


Authors

Showing all 15878 results

NameH-indexPapersCitations
Kazunori Kataoka13890870412
Yoichiro Iwakura12970564041
Kouji Matsushima12459056995
Masaki Ishitsuka10362439383
Shinsuke Tanabe9872237445
Tatsumi Koi9741150222
Hirofumi Akagi9461843179
Clifford A. Lowell9125823538
Teruo Okano9160528346
László Á. Gergely8942660674
T. Sumiyoshi8885562277
Toshinori Nakayama8640525275
Akihiko Kudo8632839475
Hans-Joachim Gabius8569928085
Motohide Tamura85100732725
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202356
2022137
20211,357
20201,481
20191,510
20181,429