Tokyo University of Science

About: Tokyo University of Science is a education organization based out in Tokyo, Japan. It is known for research contribution in the topics: Thin film & Enantioselective synthesis. The organization has 15800 authors who have published 24147 publications receiving 438081 citations. The organization is also known as: Tōkyō Rika Daigaku & Science University of Tokyo.

A new electrode material for rechargeable sodium batteries: P2-type Na2/3[Mg0.28Mn0.72]O2 with anomalously high reversible capacity

Abstract: P2-type Na2/3[Mg0.28Mn0.72]O2 is prepared and electrode performance in Na cells is first provided. The sample surprisingly delivers a large reversible capacity (220 mA h g−1) even though electrochemically inactive magnesium ions are enriched in the host structure. This new electrode material is potentially utilized for rechargeable batteries made from only earth-abundant elements.

Synthetic Double-Stranded RNA Poly(I:C) Combined with Mucosal Vaccine Protects against Influenza Virus Infection

Abstract: The mucosal adjuvant effect of synthetic double-stranded RNA polyriboinosinic polyribocytidylic acid [poly(I:C)] against influenza virus was examined under intranasal coadministration with inactivated hemagglutinin (HA) vaccine in BALB/c mice and was shown to have a protective effect against both nasal-restricted infection and lethal lung infection. Intranasal administration of vaccine from PR8 (H1N1) with poly(I:C) induced a high anti-HA immunoglobulin A (IgA) response in the nasal wash and IgG antibody response in the serum, while vaccination without poly(I:C) induced little response. Intracerebral injection confirmed the safety of poly(I:C). In addition, we demonstrated that administration of poly(I:C) with either A/Beijing (H1N1) or A/Yamagata (H1N1) vaccine conferred complete protection against PR8 challenge in this mouse nasal infection model, suggesting that poly(I:C) possessed cross-protection ability against variant viruses. To investigate the mechanism of the protective effect of poly(I:C), mRNA levels of Toll-like receptors and cytokines were examined in the nasal-associated lymphoid tissue after vaccination or virus challenge. Intranasal administration of HA vaccine with poly(I:C) up-regulated expression of Toll-like receptor 3 and alpha/beta interferons as well as Th1- and Th2-related cytokines. We propose that poly(I:C) is a new effective intranasal adjuvant for influenza virus vaccine.

Torque Density and Efficiency Improvements of a Switched Reluctance Motor Without Rare-Earth Material for Hybrid Vehicles

Abstract: A machine design of a switched reluctance motor having competitive torque and efficiency as well as compactness with respect to an interior permanent-magnet (IPM) synchronous motor (IPMSM) in a hybrid electric vehicle (Toyota Prius 2003) has been investigated. A torque of 400 N·m is set as a target with an outer diameter of 269 mm with an axial length of 156 mm, including coil end lengths. In addition, a 50-kW field weakening capability must be competitive to the IPMSM. The highest efficiency of 95% is also aimed. Stator and rotor structures and iron material are investigated. Test machines are built. Static and light load tests are carried out.