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Institution

Tufts University

EducationMedford, Massachusetts, United States
About: Tufts University is a education organization based out in Medford, Massachusetts, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 32800 authors who have published 66881 publications receiving 3451152 citations. The organization is also known as: Tufts College & Universitatis Tuftensis.


Papers
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Journal ArticleDOI
TL;DR: In this paper, the authors proposed a method for predicting and preventing sudden cardiac death (SCD) in the general population, which can manifest as ventricular tachycardia, ventricular fibrillation (VF), pulseless electric activity (PEA), or asystole.
Abstract: Despite the significant decline in coronary artery disease (CAD) mortality in the second half of the 20th century,1 sudden cardiac death (SCD) continues to claim 250 000 to 300 000 US lives annually.2 In North America and Europe the annual incidence of SCD ranges between 50 to 100 per 100 000 in the general population.3,–,6 Because of the absence of emergency medical response systems in most world regions, worldwide estimates are currently not available.7 However, even in the presence of advanced first responder systems for resuscitation of out-of-hospital cardiac arrest, the overall survival rate in a recent North American analysis was 4.6%.8 SCD can manifest as ventricular tachycardia (VT), ventricular fibrillation (VF), pulseless electric activity (PEA), or asystole. In a significant proportion of patients, SCD can present without warning or a recognized triggering mechanism. The mean age of those affected is in the mid 60s, and at least 40% of patients will suffer SCD before the age of 65.4 Consequently, enhancement of methodologies for prediction and prevention of SCD acquires a unique and critical importance for management of this significant public health issue. Prediction and prevention of SCD is an area of active investigation, but considerable challenges persist that limit the efficacy and cost-effectiveness of available methodologies.7,9,10 It was recognized early on that optimization of SCD risk stratification will require integration of multi-disciplinary efforts at the bench and bedside, with studies in the general population.11,–,13 This integration has yet to be effectively accomplished. There is also increasing awareness that more investigation needs to be directed toward identification of early predictors of SCD.14 Significant advancements have occurred for risk prediction in the inherited channelopathies15,–,17 and …

540 citations

Journal ArticleDOI
TL;DR: The composite system of nanostructured gold and cerium oxide, with a gold loading 5-8 wt%, is reported in this article as a very good catalyst for low-temperature water-gas shift.
Abstract: The composite system of nanostructured gold and cerium oxide, with a gold loading 5–8 wt%, is reported in this work as a very good catalyst for low-temperature water–gas shift. Activity depends largely on the presence of nanosized ceria particles. Various techniques of preparation of an active catalyst are disscussed. The presence of gold is crucial for activity below 300°C. A dramatic effect of gold on the reducibility of the surface oxygen of ceria is found by H2-TPR, from 310–480°C to 25–110°C. All of the available surface oxygen was reduced, while there was no effect on the bulk oxygen of ceria. This correlates well with the shift activity of the Au–ceria system.

539 citations

Journal ArticleDOI
TL;DR: Environmental factors, possibly including infectious agents through urinary tract infections or chemicals contained in cigarette smoke, may induce PBC in genetically susceptible individuals and exogenous estrogens may also contribute to explain the female predominance of the disease.

539 citations

Journal ArticleDOI
TL;DR: Losartan 150 mg daily reduced the rate of death or admission for heart failure in patients with heart failure, reduced left-ventricular ejection fraction, and intolerance to ACE inhibitors compared with losartan 50 mg daily, and shows the value of up-titrating ARB doses to confer clinical benefit.

538 citations

Journal ArticleDOI
David Hammer1
TL;DR: This paper described a study of such epistemological beliefs in the context of an introductory physics course and interviewed 6 students, meeting several times with each over one semester, through the development and use of an analytic framework.
Abstract: Students' beliefs about knowledge and learning in a domain may have a significant effect on how they approach the material and on what they learn. This article describes a study of such epistemological beliefs in the context of an introductory physics course. I interviewed 6 students, meeting several times with each over one semester. The interviews involved a variety of conversations and tasks closely tied to the course. Through the development and use of an analytic framework, it was possible to characterize subjects' beliefs. The framework consisted of three dimensions:

538 citations


Authors

Showing all 33110 results

NameH-indexPapersCitations
Walter C. Willett3342399413322
Frank B. Hu2501675253464
Ralph B. D'Agostino2261287229636
John Q. Trojanowski2261467213948
Peter Libby211932182724
David Baltimore203876162955
Eric B. Rimm196988147119
Lewis C. Cantley196748169037
Bernard Rosner1901162147661
Charles A. Dinarello1901058139668
William B. Kannel188533175659
Scott M. Grundy187841231821
John P. A. Ioannidis1851311193612
David H. Weinberg183700171424
Joel Schwartz1831149109985
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023100
2022467
20213,334
20203,065
20192,806
20182,618