Institution
Tufts University
Education•Medford, Massachusetts, United States•
About: Tufts University is a education organization based out in Medford, Massachusetts, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 32800 authors who have published 66881 publications receiving 3451152 citations. The organization is also known as: Tufts College & Universitatis Tuftensis.
Papers published on a yearly basis
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TL;DR: In this paper, the authors report that characterization of Vibrio cholerae from human stools supports a model whereby human colonization creates a hyperinfectious bacterial state that is maintained after dissemination and that may contribute to epidemic spread of cholera.
Abstract: The factors that enhance the transmission of pathogens during epidemic spread are ill defined. Water-borne spread of the diarrhoeal disease cholera occurs rapidly in nature, whereas infection of human volunteers with bacteria grown in vitro is difficult in the absence of stomach acid buffering1. It is unclear, however, whether stomach acidity is a principal factor contributing to epidemic spread2. Here we report that characterization of Vibrio cholerae from human stools supports a model whereby human colonization creates a hyperinfectious bacterial state that is maintained after dissemination and that may contribute to epidemic spread of cholera. Transcriptional profiling of V. cholerae from stool samples revealed a unique physiological and behavioural state characterized by high expression levels of genes required for nutrient acquisition and motility, and low expression levels of genes required for bacterial chemotaxis.
506 citations
TL;DR: An essential role for DJ-1 in dopaminergic physiology and D2 receptor-mediated functions is suggested in dopamine overflow in the striatum and in the inhibitory effects of D2 autoreceptor stimulation.
506 citations
TL;DR: Discovery of the biochemical differences that account for the higher membrane potentials in carcinoma cells is expected to lead to the design of new DLCs targeted specifically to those differences, resulting in even greater selectivity and efficacy for tumor cell killing.
506 citations
TL;DR: It may be that an optimal diet with a balance of n‐6 and n‐3 fatty acids may help to delay their onset or reduce the insult to brain functions which these diseases elicit.
505 citations
TL;DR: In this article, detailed measurements of the electron performance of the ATLAS detector at the LHC were reported, using decays of the Z, W and J/psi particles.
Abstract: Detailed measurements of the electron performance of the ATLAS detector at the LHC are reported, using decays of the Z, W and J/psi particles. Data collected in 2010 at root s = 7 TeV are used, corresponding to an integrated luminosity of almost 40 pb(-1). The inter-alignment of the inner detector and the electromagnetic calorimeter, the determination of the electron energy scale and resolution, and the performance in terms of response uniformity and linearity are discussed. The electron identification, reconstruction and trigger efficiencies, as well as the charge misidentification probability, are also presented.
505 citations
Authors
Showing all 33110 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Walter C. Willett | 334 | 2399 | 413322 |
| Frank B. Hu | 250 | 1675 | 253464 |
| Ralph B. D'Agostino | 226 | 1287 | 229636 |
| John Q. Trojanowski | 226 | 1467 | 213948 |
| Peter Libby | 211 | 932 | 182724 |
| David Baltimore | 203 | 876 | 162955 |
| Eric B. Rimm | 196 | 988 | 147119 |
| Lewis C. Cantley | 196 | 748 | 169037 |
| Bernard Rosner | 190 | 1162 | 147661 |
| Charles A. Dinarello | 190 | 1058 | 139668 |
| William B. Kannel | 188 | 533 | 175659 |
| Scott M. Grundy | 187 | 841 | 231821 |
| John P. A. Ioannidis | 185 | 1311 | 193612 |
| David H. Weinberg | 183 | 700 | 171424 |
| Joel Schwartz | 183 | 1149 | 109985 |