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Institution

Tufts University

EducationMedford, Massachusetts, United States
About: Tufts University is a education organization based out in Medford, Massachusetts, United States. It is known for research contribution in the topics: Population & Medicine. The organization has 32800 authors who have published 66881 publications receiving 3451152 citations. The organization is also known as: Tufts College & Universitatis Tuftensis.


Papers
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Journal ArticleDOI
TL;DR: In this article, the authors exploit large variation in recent temperature and precipitation trends to identify adaptation to climate change in US agriculture, and use this information to generate new estimates of the potential impact of future climate change on agricultural outcomes.
Abstract: Understanding the potential impacts of climate change on economic outcomes requires knowing how agents might adapt to a changing climate. We exploit large variation in recent temperature and precipitation trends to identify adaptation to climate change in US agriculture, and use this information to generate new estimates of the potential impact of future climate change on agricultural outcomes. Longer run adaptations appear to have mitigated less than half—and more likely none—of the large negative short-run impacts of extreme heat on productivity. Limited recent adaptation implies substantial losses under future climate change in the absence of countervailing investments. (JEL Q11, Q15, Q51, Q54)

505 citations

Journal ArticleDOI
TL;DR: The early important empirical works on policymaking in Washington were built around elite interviews as mentioned in this paper, and there are few other contemporary political scientists working on public policymaking who have built reputations for their methodological skills as interviewers.
Abstract: Many of the early important empirical works on policymaking in Washington were built around elite interviews. We first learned about how Congress really operates from pioneers in elite interviewing such as Lewis Anthony Dexter (1969), Ralph Huitt (1969), and Donald Matthews (1960). No less revered is the scholarship of Richard Fenno (1978), John Kingdon (1995), and Robert Salisbury (1993), who have produced enduring and respected work from elite interviewing. Yet there are few other contemporary political scientists working on public policymaking who have built reputations for their methodological skills as interviewers. Elite interviewing is still widely used as the basis for collecting data, but most interviewing depends on a few trusted templates. Most commonly, elites in a particular institution are chosen at random and subjected to the same interview protocol composed of structured or semistructured questions. For example, state legislators are asked a series of questions about their attitudes on particular issues or institutional practices. Or policymakers involved in certain issues are selected and then quizzed about those matters. Some confident and skilled interviewers, like William Browne (1988) and Richard Hall (1996), combine different interview approaches in their work but they are the exceptions and not the rule.

505 citations

Journal ArticleDOI
TL;DR: A wealth of literature on the role of chaperones and foldases in in vivo protein folding has triggered the development of new additives and processes that mimic chaperone activity in vitro.

505 citations

Journal ArticleDOI
28 Oct 2004-Nature
TL;DR: The eight-chromosome ∼9.2-million-base genome of C. hominis shows a striking concordance with the requirements imposed by the environmental niches the parasite inhabits, and phenotypic differences between these parasites must be due to subtle sequence divergence.
Abstract: Cryptosporidium species cause acute gastroenteritis and diarrhoea worldwide. They are members of the Apicomplexa--protozoan pathogens that invade host cells by using a specialized apical complex and are usually transmitted by an invertebrate vector or intermediate host. In contrast to other Apicomplexans, Cryptosporidium is transmitted by ingestion of oocysts and completes its life cycle in a single host. No therapy is available, and control focuses on eliminating oocysts in water supplies. Two species, C. hominis and C. parvum, which differ in host range, genotype and pathogenicity, are most relevant to humans. C. hominis is restricted to humans, whereas C. parvum also infects other mammals. Here we describe the eight-chromosome approximately 9.2-million-base genome of C. hominis. The complement of C. hominis protein-coding genes shows a striking concordance with the requirements imposed by the environmental niches the parasite inhabits. Energy metabolism is largely from glycolysis. Both aerobic and anaerobic metabolisms are available, the former requiring an alternative electron transport system in a simplified mitochondrion. Biosynthesis capabilities are limited, explaining an extensive array of transporters. Evidence of an apicoplast is absent, but genes associated with apical complex organelles are present. C. hominis and C. parvum exhibit very similar gene complements, and phenotypic differences between these parasites must be due to subtle sequence divergence.

504 citations

Journal ArticleDOI
03 Jul 2009-Science
TL;DR: The analysis of the data from the Phoenix mission revealed an alkaline environment, in contrast to that found by the Mars Exploration Rovers, indicating that many different environments have existed on Mars.
Abstract: The Phoenix mission investigated patterned ground and weather in the northern arctic region of Mars for 5 months starting 25 May 2008 (solar longitude between 76.5° and 148°). A shallow ice table was uncovered by the robotic arm in the center and edge of a nearby polygon at depths of 5 to 18 centimeters. In late summer, snowfall and frost blanketed the surface at night; H2O ice and vapor constantly interacted with the soil. The soil was alkaline (pH = 7.7) and contained CaCO3, aqueous minerals, and salts up to several weight percent in the indurated surface soil. Their formation likely required the presence of water.

503 citations


Authors

Showing all 33110 results

NameH-indexPapersCitations
Walter C. Willett3342399413322
Frank B. Hu2501675253464
Ralph B. D'Agostino2261287229636
John Q. Trojanowski2261467213948
Peter Libby211932182724
David Baltimore203876162955
Eric B. Rimm196988147119
Lewis C. Cantley196748169037
Bernard Rosner1901162147661
Charles A. Dinarello1901058139668
William B. Kannel188533175659
Scott M. Grundy187841231821
John P. A. Ioannidis1851311193612
David H. Weinberg183700171424
Joel Schwartz1831149109985
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023100
2022467
20213,335
20203,065
20192,806
20182,618