Institution
Tufts University
Education•Medford, Massachusetts, United States•
About: Tufts University is a education organization based out in Medford, Massachusetts, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 32800 authors who have published 66881 publications receiving 3451152 citations. The organization is also known as: Tufts College & Universitatis Tuftensis.
Papers published on a yearly basis
Papers
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TL;DR: Survival among mechanically ventilated patients depends not only on the factors present at the start of mechanical ventilation, but also on the development of complications and patient management in the intensive care unit.
Abstract: ContextThe outcome of patients receiving mechanical ventilation for particular
indications has been studied, but the outcome in a large number of unselected,
heterogeneous patients has not been reported.ObjectiveTo determine the survival of patients receiving mechanical ventilation
and the relative importance of factors influencing survival.Design, Setting, and SubjectsProspective cohort of consecutive adult patients admitted to 361 intensive
care units who received mechanical ventilation for more than 12 hours between
March 1, 1998, and March 31, 1998. Data were collected on each patient at
initiation of mechanical ventilation and daily throughout the course of mechanical
ventilation for up to 28 days.Main Outcome MeasureAll-cause mortality during intensive care unit stay.ResultsOf the 15 757 patients admitted, a total of 5183 (33%) received
mechanical ventilation for a mean (SD) duration of 5.9 (7.2) days. The mean
(SD) length of stay in the intensive care unit was 11.2 (13.7) days. Overall
mortality rate in the intensive care unit was 30.7% (1590 patients) for the
entire population, 52% (120) in patients who received ventilation because
of acute respiratory distress syndrome, and 22% (115) in patients who received
ventilation for an exacerbation of chronic obstructive pulmonary disease.
Survival of unselected patients receiving mechanical ventilation for more
than 12 hours was 69%. The main conditions independently associated with increased
mortality were (1) factors present at the start of mechanical ventilation
(odds ratio [OR], 2.98; 95% confidence interval [CI], 2.44-3.63; P<.001 for coma), (2) factors related to patient management (OR,
3.67; 95% CI, 2.02-6.66; P<.001 for plateau airway
pressure >35 cm H2O), and (3) developments occurring over the course
of mechanical ventilation (OR, 8.71; 95% CI, 5.44-13.94; P<.001 for ratio of PaO2 to fraction of inspired oxygen
<100).ConclusionSurvival among mechanically ventilated patients depends not only on
the factors present at the start of mechanical ventilation, but also on the
development of complications and patient management in the intensive care
unit.
1,621 citations
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TL;DR: Additional research will be needed to clarify the exact role of each component of the fear circuitry in the anxiety disorders, determine whether functional abnormalities identified in the Anxiety disorders represent acquired signs of the disorders or vulnerability factors that increase the risk of developing them, and use functional neuroimaging to predict treatment response and assess treatment-related changes in brain function.
1,617 citations
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Christopher J L Murray1, Ryan M Barber, Kyle J Foreman2, Ayse Abbasoglu Ozgoren +608 more•Institutions (251)
TL;DR: Patterns of the epidemiological transition with a composite indicator of sociodemographic status, which was constructed from income per person, average years of schooling after age 15 years, and the total fertility rate and mean age of the population, were quantified.
1,609 citations
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TL;DR: Emerging soft-bodied robotic systems are reviewed to endow robots with new, bioinspired capabilities that permit adaptive, flexible interactions with unpredictable environments and to reduce the mechanical and algorithmic complexity involved in robot design.
1,604 citations
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TL;DR: The number of adults with raised blood pressure increased from 594 million in 1975 to 1·13 billion in 2015, with the increase largely in low-income and middle-income countries, and the contributions of changes in prevalence versus population growth and ageing to the increase.
1,573 citations
Authors
Showing all 33110 results
Name | H-index | Papers | Citations |
---|---|---|---|
Walter C. Willett | 334 | 2399 | 413322 |
Frank B. Hu | 250 | 1675 | 253464 |
Ralph B. D'Agostino | 226 | 1287 | 229636 |
John Q. Trojanowski | 226 | 1467 | 213948 |
Peter Libby | 211 | 932 | 182724 |
David Baltimore | 203 | 876 | 162955 |
Eric B. Rimm | 196 | 988 | 147119 |
Lewis C. Cantley | 196 | 748 | 169037 |
Bernard Rosner | 190 | 1162 | 147661 |
Charles A. Dinarello | 190 | 1058 | 139668 |
William B. Kannel | 188 | 533 | 175659 |
Scott M. Grundy | 187 | 841 | 231821 |
John P. A. Ioannidis | 185 | 1311 | 193612 |
David H. Weinberg | 183 | 700 | 171424 |
Joel Schwartz | 183 | 1149 | 109985 |