Institution
Tulane University
Education•New Orleans, Louisiana, United States•
About: Tulane University is a education organization based out in New Orleans, Louisiana, United States. It is known for research contribution in the topics: Population & Blood pressure. The organization has 24478 authors who have published 47205 publications receiving 1944993 citations. The organization is also known as: University of Louisiana.
Topics: Population, Blood pressure, Receptor, Poison control, Medicine
Papers published on a yearly basis
Papers
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Memorial Sloan Kettering Cancer Center1, University of Chicago2, University of Washington3, University of North Carolina at Chapel Hill4, Université Paris-Saclay5, Johns Hopkins University6, Oregon Health & Science University7, University of British Columbia8, University of Texas MD Anderson Cancer Center9, University of Virginia10, Duke University11, Wayne State University12, University of Michigan13, Thomas Jefferson University14, University of Wisconsin-Madison15, Cornell University16, Rutgers University17, University of California, San Francisco18, Tulane University19, Harvard University20, Columbia University21
TL;DR: The concept of no longer clinically benefiting is introduced to underscore the distinction between first evidence of progression and the clinical need to terminate or change treatment, and the importance of documenting progression in existing lesions as distinct from the development of new lesions.
Abstract: PurposeEvolving treatments, disease phenotypes, and biology, together with a changing drug development environment, have created the need to revise castration-resistant prostate cancer (CRPC) clinical trial recommendations to succeed those from prior Prostate Cancer Clinical Trials Working Groups.MethodsAn international expert committee of prostate cancer clinical investigators (the Prostate Cancer Clinical Trials Working Group 3 [PCWG3]) was reconvened and expanded and met in 2012-2015 to formulate updated criteria on the basis of emerging trial data and validation studies of the Prostate Cancer Clinical Trials Working Group 2 recommendations.ResultsPCWG3 recommends that baseline patient assessment include tumor histology, detailed records of prior systemic treatments and responses, and a detailed reporting of disease subtypes based on an anatomic pattern of metastatic spread. New recommendations for trial outcome measures include the time to event end point of symptomatic skeletal events, as well as tim...
938 citations
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TL;DR: In this paper, the authors present a theoretical framework for defining hegemonic masculinity and multiple femininities that allows for multiple configurations within each, and that can be used empirically across settings and groups.
Abstract: R. W. Connell’s path-breaking notion of multiple masculinities (Connell, 1995) and hegemonic masculinity (Connell, 1987, 1995) have been taken up as central constructs in the sociology of gender. Although there has been a great deal of empirical research and theory published that has built upon and utilized Connell’s concepts, an adequate conceptualization of hegemonic femininity and multiple femininities has not yet been developed. To redress this, the author presents a theoretical framework that builds upon the insights of Connell and others, offers a definition of hegemonic masculinity and hegemonic femininity that allows for multiple configurations within each, and that can be used empirically across settings and groups. The author also outlines how hegemonic masculinity and hegemonic femininity are implicated in and intersect with other systems of inequality such as class, race, and ethnicity.
937 citations
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TL;DR: It is found that early colonies of marrow stromal cells contain a third kind of cell: very small round cells that rapidly self-renew and have a greater potential for multipotential differentiation than samples enriched for the large cells.
Abstract: Marrow stromal cells are adult stem cells from bone marrow that can differentiate into multiple nonhematopoietic cell lineages. Previous reports demonstrated that single-cell-derived colonies of marrow stromal cells contained two morphologically distinct cell types: spindle-shaped cells and large flat cells. Here we found that early colonies also contain a third kind of cell: very small round cells that rapidly self-renew. Samples enriched for the small cells had a greater potential for multipotential differentiation than samples enriched for the large cells. Also, the small cells expressed a series of surface epitopes and other proteins that potentially can be used to distinguish the small cells from the large cells. The results suggested it will be important to distinguish the major subpopulations of marrow stromal cells in defining their biology and their potential for cell and gene therapy.
932 citations
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TL;DR: Childhood measures of LDL-C level and BMI predict carotid IMT in young adults; the prevention implications of these findings remains to be explored.
Abstract: ContextCarotid artery intima-media thickness (IMT) is associated with cardiovascular
risk factors and is recognized as an important predictive measure of clinical
coronary atherosclerosis events in middle-aged and elderly populations. However,
information on the association of carotid IMT in young adults with different
risk factors measured in childhood, adulthood, or as a cumulative burden of
each of the risk factors measured serially from childhood to adulthood is
limited.ObjectiveTo examine the association between carotid IMT in young adults and traditional
cardiovascular risk factors measured since childhood.Design, Setting, and ParticipantsA cohort study of 486 adults aged 25 to 37 years from a semirural black
and white community in Bogalusa, La (71% white, 39% men), who had at least
3 measurements of traditional risk factors since childhood, conducted between
September 1973 and December 1996.Main Outcome MeasureAssociation of carotid IMT with risk factors, including systolic blood
pressure, lipoprotein levels, and body mass index.ResultsMale vs female (0.757 mm vs 0.719 mm) and black vs white (0.760 mm vs
0.723 mm) participants had increased carotid IMT (P<.001
for both). In multivariable analyses, significant predictors for being in
top vs lower 3 quartiles of carotid IMT in young adults were childhood measures
of low-density lipoprotein cholesterol (LDL-C) level (odds ratio [OR], 1.42,
corresponding to 1-SD change specific for age, race, and sex; 95% confidence
interval [CI], 1.14-1.78) and body mass index (BMI; OR, 1.25; 95% CI, 1.01-1.54);
adulthood measures of LDL-C level (OR, 1.46; 95% CI, 1.16-1.82), high-density
lipoprotein cholesterol (HDL-C) level (OR, 0.67; 95% CI, 0.51-0.88), and systolic
blood pressure (OR, 1.36; 95% CI, 1.08-1.72); and long-term cumulative burden
of LDL-C (OR, 1.58; 95% CI, 1.24-2.01) and HDL-C (OR, 0.75; 95% CI, 0.58-0.97)
levels measured serially from childhood to adulthood. An increasing trend
in carotid IMT across quartiles of LDL-C level measured in childhood was observed,
with a mean value of 0.761 mm (95% CI, 0.743-0.780 mm) for those at the top
quartile vs 0.724 mm (95% CI, 0.715-0.734 mm) for those in the lower 3 quartiles
(P<.001).ConclusionsChildhood measures of LDL-C level and BMI predict carotid IMT in young
adults. The prevention implications of these findings remains to be explored.
930 citations
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TL;DR: In this paper, the authors investigate whether brand names are more valuable online or in traditional supermarkets and whether the increasing availability of comparative price information online makes consumers more price-sensitive, and find that brand names become more important online in some categories but not in others depending on the extent of information available to consumers.
921 citations
Authors
Showing all 24722 results
Name | H-index | Papers | Citations |
---|---|---|---|
Walter C. Willett | 334 | 2399 | 413322 |
JoAnn E. Manson | 270 | 1819 | 258509 |
Frank B. Hu | 250 | 1675 | 253464 |
Eric B. Rimm | 196 | 988 | 147119 |
Krzysztof Matyjaszewski | 169 | 1431 | 128585 |
Nicholas J. White | 161 | 1352 | 104539 |
Tien Yin Wong | 160 | 1880 | 131830 |
Tomas Hökfelt | 158 | 1033 | 95979 |
Thomas E. Starzl | 150 | 1625 | 91704 |
Geoffrey Burnstock | 141 | 1488 | 99525 |
Joseph Sodroski | 138 | 542 | 77070 |
Glenn M. Chertow | 128 | 764 | 82401 |
Darwin J. Prockop | 128 | 576 | 87066 |
Kenneth J. Pienta | 127 | 671 | 64531 |
Charles Taylor | 126 | 741 | 77626 |